Christmas Calm: Our Top Nutritional Tips to Support Your Canine

Christmas can be a little chaotic at the best of times; some of our companions love the attention from all the visitors, but some can get a little overwhelmed.  There are many strategies that we can employ for our furry friends to get through this time of year unscathed, but we can also support them nutritionally too!‍ Here are our top nutritional tips for canines this Christmas.‍ Max Out On Magnesium!‍ Magnesium excretion is increased during times of stress. Catecholamines and corticosteroids enhance the shift of magnesium from inside the cell to outside of the cell leading to increased urinary excretion. In turn, low magnesium levels increase the release of stress-associated hormones. This unfortunately creates a cycle of a reduced resistance to stress.  Offer your dog plenty of magnesium rich foods like leafy greens, nuts and seeds.‍ Time for Tea!‍ L-Theanine is seen to facilitate the generation of alpha waves which are indicative of a relaxed but awake and alert state. L-Theanine helps regulate the usual stress responses like increased blood pressure, heart rate and cortisol secretion and it’s found in our trusty tea!  Green tea packs the highest content, so brew up a cup of decaf and share it with your pooch this Christmas.‍ Dose up on D!‍ Did you know that Vitamin D deficiency is associated with increased anxiety scores?  Whilst we know it plays a role in immune function, it also contributes to cognitive function along with mood and behaviour.  Add plenty of fresh foods containing Vitamin D to your dog’s bowl, including: liver, fish and eggs!  Mushrooms are a great source too, and if you keep them in the windowsill, you’ll get even more Vitamin D too!  Always remember to saute mushrooms before feeding.‍ Build Up Your B’s!‍ B vitamins are heavily involved in the synthesis and breakdown of stress hormones.  Whenever we or our dogs are stressed, we release a cascade of hormones that help us manage the threat in front of us.  When the threat has passed, those hormones need to be broken down so our bodily functions can return to normal.  It goes without saying, the more often our bodies have to do this, the higher the demand for B vitamins (and more).  B vitamins are water-soluble, meaning they need to be replenished daily, and this is even without any stressors we may be facing.  Offer your dog plenty of sources of B vitamins in their bowls like seafood, poultry, red meat, leafy greens and seeds!‍ Our wonderful Calm Complex provides all of the above. br]‍ br]‍ Fill up on Ferments!‍ This may not apply to all dogs; especially if you are tackling an itchy issue, but there is increasing data highlighting that poor microbial diversity in the gut is linked with increased scores of anxiety.  A great way to support microbial diversity is to ensure the diet contains both pre and probiotic foods.  Prebiotic sources include: mushrooms, dandelion greens, garlic, burdock root and more.  Probiotic foods include fermented products like kefir.‍ Aside from certain nutrients, we also know how important chewing is in engaging the parasympathetic nervous system – which is the rest and digest side of the stress response.  This is why offering whole foods, which take some chewing, is great for your dog’s physical and emotional health.‍ Why Dogs Need To Chew‍ Other top (non-nutritional) tips for supporting your overwhelmed canine this Christmas:‍ Set up a safe space – this can be a covered crate or simply a quiet spot somewhere in the house. Try to maintain as much of the routine as possible, Head out on walks when it’s quiet – when everyone is driving home for Christmas at the same time, it can get a little unnerving for your anxious pooch.‍ If you would like any support with your pets, then please check out our services.‍ Thanks for reading,‍ MPN Team

3 Pillars for Pet Guardian Health This Winter

For some, December is the most exciting month of the year, for others, we can feel like we’re dragging ourselves to the New Year, either way, it’s pretty typical for self-care to high-tail it out of the window.  We’re not talking warm baths and scented candles, we’re talking basic human needs; like mealtimes and movement.‍ When we’re burning the candle at both ends, are we able to care for our pets as much as we’d like?‍ Here at My Pet Nutritionist we value pet guardian health alongside their furry counterpart’s, so in a slightly different blog than usual, we thought we’d give you our top tips for human health this winter.‍ 1)Sleep! If we listen to the old adage we should rise with the sun and sleep when it’s dark, then we’d spend most of the winter sleeping (geographical location depending of course), but there is some method in this madness.  Sleep is vital for health.‍ Sleep not only supports immune function but it also plays a key role in optimal mental health.‍ Poor sleep is regularly linked to depression, anxiety and other mental health challenges.  Sufficient REM sleep facilitates the processing of emotional information, which can be even more important for some people at this time of year.‍ The other thing to consider at this time of year is that Seasonal Affective Disorder is a subtype of depression which also affects people during reduced daylight hours.  It is closely related to the disruption of internal biological clocks.‍ Sleeping when it is dark is essential, but in the winter we rely heavily on artificial lights which can knock us out of sync.  It’s important to keep to our typical routine wherever possible.  Chrononutrition is the study of how when we eat influences our health – for example, shift workers eating during nighttime have reduced insulin tolerance compared to those who eat during the day.  Furthermore, rising early, and feeling alert when doing so is linked with better dietary control.  In other words, we are more likely to make good food choices if we rise with the sun, and go to bed with the moon.‍ Top Tips for Improved Sleep Try grounding – Studies have shown that walking barefoot outside (where safe – think on the grass in the garden) improves both sleep and mood.  It’s a little more difficult in the winter, unless you want cold and muddy feet, but grounding mats may be worth looking into. Try blue blockers – artificial light suppresses melatonin production and this is the hormone that helps us feel sleepy.  Most of us head to bed with our phones or shortly after watching TV for a couple of hours.  Consider looking at blue blockers for screen time and try to disconnect from technology completely for a couple of hours before bed.  Engaging in that heated discussion on social media just before bed results in your body amping up, not calming down, so be realistic on whether it’s the blue light keeping you awake or what you’re exposing yourself to. Increase oxygen in your bedroom – some of the best “oxygen boosting” plants include: English Ivy, Aloe Vera, Areca Palm, Snake Plant and Peace Lily. Avoid excitotoxins in your diet – you tend to find excitotoxins in processed foods, but they do go by a range of names including: carrageenan, MSG, aspartame, E numbers, BHT and other preservatives.  Just like the name suggests they ramp up activity in your nervous system – which isn’t ideal if you’re trying to settle for the evening.‍ 2)Get Outside! Being dog owners, we tend to head out in all weathers anyway, but this really is so important for our health.  Not only the cardiovascular benefits of physical exercise, but just simply being outside in nature.‍ Our species has existed for thousands upon thousands of years – but even the oldest cities have only been around a fraction of that!  What this means is that we largely evolved in nature, and this environment therefore shaped our brains – for want of a better phrase, going back to nature almost takes us back to our roots.‍ Being in nature is seen to improve sleep scores Spending time in green spaces simply makes us happier Mental stress scores significantly reduce when we live in urban areas with increased green spaces Time in nature improves our relationships with others and also cognitive functioning‍ It’s easy to look outside at the pouring rain and opt for some enrichment games instead, especially if your ever-expanding to-do -list is staring back at you, but we know that being in nature supports our stress resilience and tolerance.  Heading out for that brisk walk could be just what you need.‍ 3)Eat Well! At this time of year, we can all say we eat very well.  As we’re filling up on those moreish foods, we need to ensure we’re getting plenty of the nutrient dense ones too!‍ Every cell in every body has a job to do, and to do that job, it needs certain compounds; we get those compounds largely from the diet.‍ Particularly at this time of year, we may be interested in foods to support our immune function and our mental health.‍ Vitamin C helps encourage the production of white blood cells known as lymphocytes and phagocytes, which help protect the body against infection.  Sources of Vitamin C include red bell peppers and of course oranges.‍ Vitamin A helps maintain structural and functional integrity of mucosal cells in innate barriers (skin, respiratory tract etc).  It is also important for the functioning of natural killer cells, macrophages, and neutrophils.  In the adaptive immune response, vitamin A is necessary for the functioning of T and B cells and therefore for the generation of antibody responses to an antigen.‍ Beta carotene is converted to Vitamin A in the body but beta carotene, like all carotenoids is an antioxidant, which protects the body from free radicals.  Free radicals are produced by macrophages whilst fighting off invading germs, and these

Feeding Bones: A Mini Guide To Bones

Whether you are a seasoned raw feeder or simply want to include raw meaty bones as a way to support dental hygiene for your dog, knowing which bones to feed can be a bit of a minefield.‍ It’s a question we get asked here a lot at My Pet Nutritionist, so we thought we’d put together a handy guide on feeding bones to your dog.  We’ll look at the do’s and don’ts and the why’s and wherefores.‍ Why Feed Bones? Depending on the approach you have in feeding your dog, bones will either provide recreational enrichment and dental health support, or a solid 10% of their diet.‍ Bones as Enrichment and Stress Relief‍ Study after study have demonstrated that chewing can counter the effects of stress.  Not only does it reduce stress hormone levels, but it also limits sensory processing of external stressors.  In short, it keeps your dog’s attention off things it doesn’t need to be paying attention to.‍ At the same time, chewing is known to improve alertness; it shortens reaction time and increases vigilance.  This is thought to be due to the increase in heart rate during the chewing task which increases cerebral blood flow and brain activity.‍ So, chewing for the dog can help them rebalance their stress levels and also improve their alertness, which may be of interest if you are preparing training sessions‍ In rest and recovery, chewing opportunities need to be in a quiet space where rest can be encouraged.  The increase in heart rate and blood flow, soon dissipates, and with the limited processing of external stressors, the dog is prepared to rest.‍ At the other end of the scale, to promote alertness, offer a chewing opportunity 15-30 minutes before training.  This will vary from dog to dog, so it may take some time to find the sweet spot.‍ What is also interesting, is the rate of force needed when chewing, especially when we are encouraging dogs to rest and recover.  A strong chewing force induces a greater reduction in stress levels.  So, in this situation, larger bones may be more appropriate.‍ Bones for Dental Health Periodontal disease begins when bacteria in the dog’s mouth forms to create a substance called plaque.  The plaque sits on the surface of the teeth and with the help of saliva, it hardens to form tartar.  Not only does it sit on the teeth, plaque and tartar seeps into gum lines which causes inflammation.  Over a period of time, this inflammation and presence of bacteria causes damage to the structures surrounding the teeth; causing receding gum lines and eventually tooth loss.‍ Not only is the mouth and teeth a concern, but the bacteria found in the mouth of your dog can be released into the circulatory system, which then travels through the body.  It has been found to damage cardiac tissue causing endocarditis (infection and inflammation in the heart).  Oral health is gaining more and more attention in the human realms for its implication in a range of diseases.  Much of this we can transfer to our canine companions which means optimising their dental health is of paramount importance.‍ There are a number of chews on the market promoting oral health, but it is actually the mechanism of chewing that helps to reduce build up.‍ Chewing stimulates saliva which produces anti-bacterial agents, helping to keep the mouth clean.  Not only this, but the abrasion that occurs during chewing helps scrape deposits off the teeth.‍ So, what type of chew is best? Here’s what the data suggests:‍ Raw bones reduced mouth bacteria by 79%, Daily brushing reduced it by 70% and, Marketed dental chews reduced it by 54-60%.‍ Findings Here‍ As you can see, raw bones lead the way in reducing bacteria and therefore optimising dental health in the dog.‍ Bones as a Source of Nutrition Bone starts as a cartilage model which gets slowly replaced.  Osteoblasts are the cells that form new bone and they secrete osteoids.  Osteoid tissue is simply unmineralized bone tissue.  Soon after the osteoid is laid down, inorganic salts, like calcium and phosphorus are deposited which forms the hardened material that we know as bone.‍ As you can see, calcium and phosphorus make up a large part of the skeleton, and so when these compounds are ingested by another animal, they ingest calcium and phosphorus (amongst others).‍ In other words, when our dogs eat the bones of other animals, they are ingesting what that animal is built of.‍ Whilst calcium is the main structural component of skeleton and teeth, it also plays a role in blood clotting.  In addition, it is involved in the intracellular messaging triggering the contraction of muscle fibres.  Calcium also plays a role in fat oxidation, and it carries ATP (energy) with magnesium.‍ Calcium’s role in muscle function also includes maintaining the action of the heart muscle.  Calcium particles enter the heart muscle cells during each heartbeat and contribute to the electrical signal that coordinates its function, so it’s also vitally important to cardiovascular health.‍ Why Does My Dog Need Calcium‍ Phosphorus in mainly used for the growth and repair of body tissues – it is a component part of bones, teeth, RNA and DNA.  In the form of phospholipids, phosphorus is also a component of cell membrane structure and of the body’s key energy source, ATP.‍ Many proteins and sugars in the body are phosphorylated. In addition, phosphorus plays key roles in regulation of gene transcription, activation of enzymes, maintenance of normal pH in extracellular fluid, and intracellular energy storage.‍ As you can see, whilst they are important nutrients for skeletal health and integrity, both calcium and phosphorus also play other roles in the body.‍ But bones are also a source of sodium and magnesium too!‍ Why Does My Dog Need Minerals‍ How To Feed Bones‍ No cooked bones Feed the right size for the breed Avoid weight bearing bones Avoid hollow-marrow bones‍ Weaning/Puppies‍ Chicken necks, wings, feet, thighs Duck feet, necks Rabbit, cut Quail, cut

Why Your Dog Needs Vitamin B6 

You’ll have noticed that we talk a lot about vitamins and minerals here at My Pet Nutritionist.  There’s a reason.  For your pet’s body to do the jobs it needs to, it needs certain compounds, and that includes vitamins and minerals.‍ Vitamin B6 is one of the B complex vitamins, it is water-soluble and necessary for a range of functions.‍ Let’s take a look at it in a little more detail.‍ Vitamin B6 Vitamin B6, also known as pyridoxine, is a water-soluble vitamin that the body needs for several functions.‍ It’s significant to protein, fat and carbohydrate metabolism and the creation of red blood cells and neurotransmitters.‍ Vitamin B6 cannot be made by the body and so it must come from the diet.‍ Vitamin B6 and Behaviour The central nervous system runs on these chemical messengers called neurotransmitters.  They are like the carrier pigeons of the body.  Vitamin B6 is involved in the synthesis of a range of these neurotransmitters, specifically dopamine, serotonin and GABA.  As we know, dopamine is involved in the reward circuitry in the brain, serotonin is known as the feel good neurotransmitter and GABA is like the brakes of the nervous system; it helps calm things down.  So, if we are looking for balanced and appropriate responses to those things experienced by our dogs, they need access to sufficient levels of the right neurotransmitter.  B6 will therefore play a role.‍ In human studies we have linked vitamin B6 deficiency to depressive symptoms.‍ Findings Here‍ It is also linked to irritability.‍ Findings Here‍ A mild deficiency of B6 down-regulates GABA and serotonin synthesis, leading to the removal of inhibition of neural activity by GABA.  Disordered sleep, irrational behaviour, and compromised cardiovascular function can result.  In addition, a loss of hypothalamus-pituitary control and therefore aberrant hormone excretion.‍ Vitamin B6 also has a direct effect on immune function and gene transcription/expression and plays a role in brain glucose regulation.‍ Vitamin B6 and Brain Health Vitamin B6 is involved in managing homocysteine levels.  In many cases, high homocysteine levels are associated with cognitive impairment and decline. Deficiency in B6 is regularly linked to high levels of homocysteine found in the blood; therefore posing a risk to brain health.‍ Ensuring sufficient levels of B6 can therefore regulate homocysteine levels, and protect cognitive function.‍ Findings Here‍ Vitamin B6 and Eye Health High levels of homocysteine are also associated with age-related macular degeneration and so, B6 can therefore be beneficial in protecting eye health.‍ As we know, B6 helps regulate levels of homocysteine in the body and in studies, when taking a regular dose of B6 supplementation, the risk of age-related macular degeneration decreased by 35-40%.‍ This data was derived from human studies and so we must be careful when extrapolating to pets, but it certainly provides food for thought. In addition, other B complex vitamins were supplemented, so it would be pertinent to establish if the combination was of more benefit than single supplement.‍ Findings Here‍ Vitamin B6 and Arthritis The high levels of inflammation in the body that result from arthritis may lead to low levels of vitamin B6.  There have also been studies demonstrating that vitamin B6 can help modulate pro-inflammatory responses in cases of arthritis.‍ Findings Here‍ The bottom line?  If your dog is suffering with a chronic inflammatory condition, it would be pertinent to monitor their vitamin B6 status.‍ Vitamin B6 and Anemia Due to its role in haemoglobin production, the most common sign of low B6 is anaemia.‍ Haemoglobin is a protein that delivers oxygen to cells. When there is low haemoglobin, cells don’t get enough oxygen.  The result is anemia.‍ Signs and Symptoms of B6 Deficiency:‍ Lethargy Abnormal heart rhythm Cracked lips Mouth ulcers Weakened immune function Inflammation of the skin Confusion/irritability‍ Food Sources:‍ Pork Poultry Fish Organ Meats Eggs‍ As vitamin B6 is a water-soluble vitamin, it needs to be replenished daily in the body.‍ Risk of Depletion:‍ Hormone demands – if your dog is stress, they are at risk of depletion without sufficient supply Undernutrition Malabsorption (digestive compromise) Pyridoxine-inactivating medications (phenobarbital for example).‍ Here at My Pet Nutritionist, we advocate a fresh food diet which is rich in a variety of vitamins and minerals.  If your dog is suffering with a chronic condition, it may well affect their nutritional status, please check out our services if you would like to find out more.‍ Thanks for reading,‍ MPN Team

The Importance of Iron in Pet Health

In human realms, we trace the importance of iron back to the Egyptians, Hindus, Greeks and Romans.  During the 17th Century, iron was used to treat chlorosis (green disease) which was a condition resulting from iron deficiency.  But we didn’t really understand the importance of inorganic iron until around 1932 – this is when we found out about its role in haemoglobin synthesis.‍ As we’re always a little behind in our canine findings, we possibly still to this day don’t respect this trusty mineral as much as we should, so here at My Pet Nutritionist, we thought we’d explore it in a little more detail and it’s importance in pet health.‍ Functions of Iron‍ Oxygen transport Oxygen storage as myoglobin Energy production Cofactor for multiple enzymes Production of neurotransmitters and thyroid hormone We understand the important role of iron when we look at how tightly regulated it is in the body.‍ The body has three unique mechanisms for maintaining iron balance and preventing deficiency and overload:‍ Storage of iron Reutilisation of iron Regulation of iron absorption‍ Iron from food is mainly absorbed in the duodenum (the first part of the small intestine).  Iron can be in ferrous state (Fe2+) or ferric state (Fe3+).‍ Fe3+ is not directly absorbed, but Fe2+ is easily absorbed.‍ In the intestine, Fe3+ is converted by ferric reductases into Fe2+ and then when required by the body, iron is transported by transferrin (a blood-plasma glycoprotein) to bone marrow and other tissues.‍ Iron is required for the transport of oxygen, oxygen storage in muscle, and is also a component of energy production.‍ After absorption, any iron that isn’t needed, is stored as ferritin in the liver, spleen or bone marrow.  During times of high need, iron is then released.‍ Most of the iron in the body is contained within red blood cells.  Red blood cells have been noted to have a life span of around 115 days but when they reach the end of their life span, they release iron.  The resultant liberated iron can be reused to produce new erythrocytes in bone marrow, stored as ferritin or released back into systemic circulation.‍ Iron Disorders Iron deficiency anaemia is the common condition associated with decreased iron levels, resulting in low circulating haemoglobin and reduced myoglobin.‍ In dogs, iron deficiency anaemia is usually secondary to some form of chronic blood loss, but it is also seen in puppies fed poor diets or who have severe parasitic infections.‍ Signs of Iron Deficiency Anaemia:‍ Pale gums Low energy Weight loss Laboured breathing Increased heart rate Signs of blood loss‍ Iron deficiency is also associated with lower T and B lymphocyte, macrophage, and neutrophil function and so immune function can be significantly compromised.‍ Your Pet’s Immune System‍ On the other side of the scale, iron toxicity is generally associated with over-the-counter supplementation.  At the cellular level, iron can impair metabolism in the heart, liver, and central nervous system.‍ Iron is generally tightly bound to proteins in the body, preventing reaction, but in times of overload it becomes available in free form which disrupts oxidative phosphorylation, catalyses lipid peroxidation, forms free radicals and ultimately leads to cell death.‍ It is this reactivity that ensures levels are tightly regulated in the body.  This is largely through absorption regulation.‍ There is no controlled mechanism for the excretion of excess iron, which would suggest that the average body would consistently possess sufficient levels.  This sadly, is not the case.‍ Daily losses for the average body are through the gastrointestinal tract via exfoliation of cells, and through the skin and urinary tract.  Periods of growth and development have higher needs and pregnancy too increases the demand.‍ Factors Affecting Absorption There are many dietary factors that affect absorption of iron and subsequently influence iron regulation in the body.‍ There are two sources of iron:‍ Haem is found primarily in meat and meat products Non-haem is found in plants.‍ Haem is generally well-absorbed, whereas non-haem absorption is largely affected by other factors.‍ Common inhibitors of iron absorption are phytates, tannins, starch, and proton pump inhibitors.‍ Phytate binds to minerals, rendering them less available and they are commonly found in nuts, grains, pulses and tubers.  Whilst tannins have been suggested to have antioxidant properties they play an inhibitory role in iron absorption.  That said, unless you offer your dog tea on a regular basis, tannins are unlikely to be an issue.‍ Proton pump inhibitors do exactly what they say on the tin.  Gastric acid is secreted from cells found in the stomach.  These cells contain proton pumps to secrete this very acid.  Proton pump inhibitor medications come along and turn off these pumps, which stops the secretion of gastric acid.‍ Unfortunately for us, stomach acid is important in releasing iron from ligands in food and in solubilizing ferric iron by converting it to ferrous form, so low levels of stomach acid can impair iron absorption and utilisation.‍ Findings Here‍ However, studies have demonstrated that when a multivitamin was administered alongside PPIs, iron absorption was not affected.  The vitamin C found in the multivitamin is thought to be protective even alongside PPI medication.‍ Vitamin C is seen as a potent facilitator of iron absorption because ascorbic acid reduces ferric to ferrous iron, which is therefore absorbable.‍ Iron Regulation The central regulator of iron homeostasis is hepcidin.  If hepcidin genes are removed, the host becomes loaded with iron.‍ Iron is regulated through a negative feedback loop.  Its presence stimulates hepcidin production and in turn blocks dietary iron absorption.  In cases of iron deficiency, hepcidin is suppressed, allowing increased absorption of dietary iron.‍ As the name suggests, hepcidin is a hormone produced in the liver and its synthesis is modulated by iron, inflammation and erythropoietic signalling.‍ High hepcidin levels are noted during times of infection and in health issues like chronic kidney disease.‍ Kidney Disease in Pets‍ High hepcidin levels block intestinal iron absorption and macrophage iron recycling, effectively withholding iron from invading pathogens.‍ Iron and Inflammation When inflammation is prolonged,

Can Cats Improve Our Health? 

We are often told that pet ownership has health benefits, the seminal work of Friedmann and colleagues in 1980 demonstrated that pet owners who suffered a heart attack were four times more likely to survive than their non-pet owning counterparts.  But we generally consider that these pet owners, in fact own dogs, and with their increase in physical activity due to the exercise requirements of the dog, it’s not a far stretch to correlate dog ownership with better physical health.‍ However, there is more and more data suggesting that cats too can improve our physical health, and most certainly our mental health.‍ So, could there be more to us keeping these feisty, stubborn, and wholly independent beings in our lives?  Here at My Pet Nutritionist, we thought we’d look into it in a little more detail.‍ Cats and Stress It seems that cat owners on the whole, are calmer when faced with stressful situations and recover much quicker than non-cat-owners.‍ The main theory behind this is that social support provides a buffer for stress; and it does, we know that having strong social networks in times of stress can mitigate the harmful effects, but it seems that cats, and pets on the whole, provide even more of a buffer.  It is thought that cats, unlike humans are non-judgemental (although many cat owners would disagree here), so not only are they a support, we’re also not worried about what they think of us.‍ We also find their purr relaxing.  Whilst it would be great to find some complex data to suggest that the frequency of the purr helps us to relax, the reality is a little less glamourous.‍ When we are sat next to our cat or they are on our lap, we instinctively pick up on their purr.  We’ll make a fuss and listen.  Quite often we start to eliminate outside noise, literally and metaphorically.  Whilst we’re focussing on their purr, we’re not thinking about that extended to do list, or that deadline we’ve got to make in work.  We are simply there, listening to a purr.  It’s a less intentional form of mindfulness.  In it’s basic definition, mindfulness is about bringing your focus to what you’re sensing or feeling at that moment.  Some owners will naturally change their breathing, slowing it down to mirror their cat.  This action stimulates the vagus nerve which is the chief of the parasympathetic nervous system.  This system is our rest and digest system, the one that counters our fight and flight.  So, often without even realising it, simply sitting, in the moment with the cat, listening to their purr, we have moderated our stress response.‍ This will also apply when we are watching them roll over in the sunshine, or play with their toys, we are simply being with them, nothing more, nothing less.‍ Cats and Relationships Whilst we’ve all heard the phrase, crazy cat person, it seems that when assessed against personality factors, cat owners are more socially sensitive, trusting and like other people more than non-cat owners.  As we mentioned earlier, social support is a buffer in times of stress, so it could be suggested that as cat owners tend to get on with other people more, they have a better social network, providing more of a buffer, therefore making them more resilient in tough times.  So, whilst owning a cat is not directly linked to better relationships, people who choose to own cats tend to possess personality traits that help them experience quality relationships.‍ Findings Here‍ This could largely be due to the hormone oxytocin.‍ This hormone plays a role in social bonding, reproduction, childbirth, and the period after childbirth.  In humans it is seen to increase when touched, when we watch an emotional movie or engage in group activities.  Humans have many oxytocin receptors compared to other animals, demonstrating our need for social interaction; affecting our central nervous system and peripheral nervous system, oxytocin is a key player in reducing stress hormones.‍ Oxytocin is known to increase when petting both cats and dogs, and it has been demonstrated that this increase, subsequently enhances trust of a stranger, meaning cat owners may be more likely to engage in new social relationships and increasing that social network.‍ Cats and Sleep Study after study have demonstrated that cat owners report they are happier, more confident, less nervous, more energetic, attentive, and less lonely.  They also report they sleep and focus better than non-cat owners.‍ Findings Here‍ All of this could in fact be due to our sleep cycles as a cat owner.‍ Humans function on a circadian rhythm, which is around a 24-hour sleep-wake cycle.  Without going into the ins and outs of it, without a sleep drive, we struggle to fall asleep.  Part of this sleep drive is the accumulation of a neurotransmitter called adenosine throughout the day.  To fall asleep, we respond to the hormone melatonin, which ramps up at night, in response to light cues.  In short, what our body experiences throughout the day affects how we sleep that night.  This is why, if anyone ever struggles to sleep, a routine is the first thing they are told to implement.‍ And, as any cat owner will attest, cats know exactly what time breakfast is!‍ Even if your cat doesn’t venture into the bedroom to claw at your feet for their breakfast, one of the first thoughts to cross a pet-owners mind in the morning is the need to get up and sort the cat/s/dog/s out.  Without knowing, us pet owners get into a routine, very quickly.  We tend to get up at the same time most days, keeping our circadian rhythm steady.  If we have better sleep hygiene, we will experience more quality sleep and therefore be more energetic throughout the day, and likely be more focussed.‍ So inadvertently, pet ownership results in a routine which keeps our sleep on track.‍ There is also the consideration that some owners allow their pets to sleep on the bed with

Should I Feed My Pet a Vegan Diet?

In October 2021, a well-known newspaper published an article which suggested vegan pet food is as healthy for cats and dogs as meat.‍ A veterinary professor argued that his research showed that cats and dogs had as good, or better health outcomes on plant-based diets as they did when fed on meat products.  However, what the headlines forget to mention is that he also said, this is on the proviso that these plant-based diets were carefully formulated with additional synthetic nutrients.  A final note, these findings remain, at present, unpublished.‍ Here at My Pet Nutritionist, we often get asked what the best diet is for our pets, so we thought we’d look into vegan and vegetarian diets in a little more detail.‍ The vegetarian diet involves avoiding meat, fish and poultry products, the vegan diet involves avoiding all animal products, this includes dairy and even honey.‍ How do they suit our cats and dogs? Let’s start with the cats.‍ No matter where you look, the jury is in – cats evolved as hunters that consume prey containing high amounts of protein, moderate amounts of fat, and minimal amounts of carbohydrates.  They are obligate carnivores.  Building on this definition, they are actually hyper carnivorous.  They are a small carnivorous animal with a proportionally large brain.  What this means is that their high brain demand for glucose could not be met by a natural prey diet, if they were to only utilise carbohydrates as glucose.  So, they are really good at producing glucose from non-carbohydrate sources like protein and fat.  This natural evolution has made them quite poor at using carbohydrates, as demonstrated by their limited amylase activity in the pancreas and small intestine (even compared to dogs).‍ The other element to consider for the cat is the well known amino acid taurine.  Cats and humans are among the few mammals whose bodies do not make taurine, and therefore must obtain it from their diet.  In humans, taurine deficiency is rare because taurine is common in meat and fish food products; and so in a meat-based diet, cats also should not become deficient.‍ In the 1970’s, Quinton R. Rogers of UC Davis showed that a taurine deficiency could cause degeneration of the retina in cat’s eyes.  Kittens born to taurine deficient mothers are often blind and show many abnormalities such as impaired gait.  For this reason, in the 1908’s new cat feeding guidelines were introduced, stating a minimum level for taurine in cat food.‍ But, in later years it was also found that taurine plays a role in regulating calcium entry into heart tissue every time it beats.  Researchers soon noticed that cats presenting with dilated cardiomyopathy also had low levels of taurine.  When taurine was supplemented in the diet, the cats recovered.‍ Findings Here‍ Arachidonic acid is another nutrient required by cats that is only available from animal sources and whilst it is an omega-6 fatty acid that is often demonised, it is actually a fatty acid that is essential for health.  It is involved in the proper function of the brain and muscles.  It, along with it’s metabolites is also involved in immune function and therefore resistance to parasites and allergen insult.‍ Let’s move on to the dogs.‍ A dog is a facultative carnivore, although some describe them as an omnivore.  It is this definition that many believe allows our canine companions well adapted to a vegetarian diet, but again, the dog demonstrates poor utilisation of carbohydrates unless in a high energy need (like lactation or speed work) by their limited amylase activity.‍ A survey of 86 vegetarian dogs in Germany, Switzerland and Belgium found that over 50% of the dogs were fed diets deficient in protein, essential amino acids, calcium, zinc, and vitamins D and B12.‍ Findings Here‍ Why Does My Dog Need Calcium‍ Why Zinc is Important For Your Dog‍ The Importance of Vitamin D for Cats and Dogs‍ Why Your Dog Needs Vitamin B12‍ Many suggest that correct formulation by manufacturers will negate these issues, Kanakubo and colleagues examined 13 dry and 11 canned vegetarian diets for dogs and cats that were sold in all or most of the United States. Crude protein and amino acid concentrations were compared with AAFCO Dog and Cat Food Nutrient Profiles. Minimum CP concentrations for the specified species and life stages were met by 23 diets; the remaining diet passed appropriate AAFCO feeding trials. However, 25% (6/24) diets did not meet all AA minimum requirements.‍ Findings Here‍ During further exploration of the companies who manufacture vegetarian diets, some even go as far as suggesting they “do not advocate the singular feeding of vegetarian or vegan diets to carnivores such as dogs and cats. … It is designed for intermittent feeding or as a base to add different meats for sensitivities and allergies”‍ If vegetarian diets are questioned on their ability to meet the nutritional needs of pets, vegan diets go one step further and avoid all animal products in their entirety, so do they suit our pets either?‍ The Journal of Animal Physiology and Animal Nutrition published a case report of two cats in March 2021.  A 2-year-old neutered Main Coon and a 1-year-old spayed domestic short hair presented to the nutrition service in France with lethargy.  Dysorexia, lethargy and muscle waste was apparent and progressive weight loss occurred in follow up consultations.  A macrocytic, non-regenerative anaemia with low serum folate were the main clinical features.  The diet was analysed, and it was found to be a plant-based, vegan pet food.  Many nutrients showed as below minimum recommendation.  Folic acid supplementation improved dysorexia and with the reintroduction of animal-derived ingredients, appetite, weight, and normal mentation was restored in both cats.‍ Case Report Here‍ Investigations have subjected commercially available vegan cat foods to blind nutritional analyses by an independent laboratory. Data shows that many brands are deficient in taurine, methionine, and arachidonic acid, with additional brands also deficient in Lysine and Arginine. Many vegan diets are also deficient in several B

What Can I Do For My Dog’s Bladder Stones

Bladder stones are exactly that, stones that form in your pet’s bladder. The more technical term is urolithiasis, which denotes the presence of uroliths in the urinary tract. These stones can develop over weeks or months, and a common question we are asked here at My Pet Nutritionist is whether dietary changes can make a difference.‍ We thought we’d focus on what bladder stones are, the different types and whether in fact dietary management is something to consider.‍ What Are Bladder Stones? Cats and dogs can be prone to developing urinary stones and infection. These occur when the concentration of certain minerals in your pet’s urine becomes too high (alkaline). In healthy pets, the urine pH is generally in the 6.5 to 7.0 range. If the pH is acidic (pH below 6) or alkaline (pH above 7) it may allow bacteria to thrive and for crystals or stones to form.‍ Stones in the bladder can cause inflammation, predispose to urinary tract infections, and even cause an obstruction of the urinary tract.‍ There are several different types of stones, and they are composed of different minerals and compounds:‍ Struvite Calcium oxalate Urate Cystine‍ The most common causes include:‍ Bacteria in the urinary tract Urinary pH Minerals present in the urine Genetics Bladder inflammation‍ Struvite Stones These stones form due to excess magnesium, ammonium and phosphorus.‍ Normal canine urine is slightly acidic and contains waste products from metabolism.  Struvite is a normal compound found in canine urine and will remain dissolved as long as the urine is acid and not too concentrated.  When the urine become too concentrated or alkaline, struvite crystals form.‍ These stones tend to form as a result of a urinary tract infection and involves an enzyme known as urease.‍ Urease is produced by the pathogenic bacteria and breaks down urea, which is normally found in urine.  In the process, excess ammonia is produced which causes the urine to become alkaline.  Excess ammonia in the urine also results in bladder inflammation, contributing to the issue.‍ These stones are generally more common in female dogs.‍ Kidney disease, long term use of diuretic medication and PPI’s can also result in alkaline urine, predisposing the dog to struvite stones.‍ Calcium Oxalate Stones The current line of thinking is that urine high in calcium, citrates, or oxalates and is acidic predisposes a dog to developing calcium oxalate urinary crystals and stones.‍ Recent studies have shown diets that cause high urine acidity (urine pH less than 6.5) may predispose dogs to develop this type of bladder stone.‍ But, like most things, there are likely other causes of calcium oxalate bladder stones too.  For example, over-usage of antibiotics may reduce numbers of the intestinal bacteria Oxalobacter formigenes whose sole nutrient is oxalate. In dogs with low populations of Oxalobacter, excess oxalate is secreted in the urine, increasing the likelihood that calcium oxalate crystals and stones can form if the urine is highly concentrated or becomes acidic.‍ Calcium oxalate uroliths are noted more commonly in male dogs and the breeds most diagnosed with both struvite and calcium oxalate bladder stones included Shih Tzus, Miniature Schnauzer, Bichon Frise, Lhasa Apso, and Yorkshire Terrier.‍ Urate Stones Urate stones are generally caused by a genetic condition in some dog breeds like Dalmatians, Jack Russel Terriers and Bulldogs. But they are also seen with liver disease, especially in dogs or cats with liver shunts.‍ Urate stones are made from compounds called purines.‍ Purines are one of the most common chemical compounds on the planet.  There are both endogenous and exogenous.  Exogenous purines are absorbed by the body through the foods eaten, and endogenous purines are made by the body itself.‍ Purines and pyrimidines are the two families of nitrogenous base that make up nucleic acids – in short, they are the building blocks of DNA and RNA.‍ Purines have a number of functions in the body:‍ Signalling molecule Provide energy Control cell growth Part of essential coenzymes Contribute to nervous system function (including neuronal development)‍ As you can see, purines perform many important functions in the cell, and so the balance between its synthesis and degradation is essential.‍ When purines are catabolised, the result is uric acid.  In all other mammals, apart from humans and Dalmatians, uric acid is then converted to allantoin, which is a very soluble excretion product.  For us humans and those unlucky dogs, we excrete uric acid through the kidneys (with some excreted through the gastrointestinal tract).‍ Uric acid is suggested to behave as a potent antioxidant. It is also thought to maintain blood pressure under low salt conditions and has been seen to function as an anti-inflammatory in certain diseases, but when levels become too high, in a condition known as hyperuricemia, problems can ensue. In humans, this can result in diseases such as kidney stones and gout and may cause hypertension. In those unlucky dogs, high uric acid levels result in bladder stones.‍ For this reason, a low purine diet is often suggested for those pets suffering urate stones.‍ Foods High in Purines‍ Organs/offal (brain, heart, liver, kidneys) Wild or Farmed Game Herring Mackerel Trout Sardines Sprats Legumes (such as kidney beans, lentils, chickpeas)‍ Foods Lower in Purines Green leafy vegetables (except spinach) Eggs Nuts Muscle meats from chicken, turkey, lamb, pork, beef, Fruits‍ If urate stones are associated with liver disease, you may want to learn more about liver disease in our other blogs.‍ Liver Disease‍ Liver Shunts‍ Foods to Feed in Liver Disease‍ Cystine Stones This is rarer in the dog, but it can occur.  This is when bladder stones are composed of cystine crystals, and it is largely genetic.‍ They are more commonly found in the following breeds:‍ Mastiff Saluki Puli Basset Hound Dachshunds‍ Findings Here‍ Cystine is an amino acid that is freely filtered in urine and almost completely reabsorbed by the kidney tubules. Sadly, an inborn error of metabolism causes high concentrations of urinary cystine in those affected dogs.‍ These stones also form in acidic environments and in

Prebiotics Vs. Probiotics

Being Global Prebiotic Week and something we are asked about regularly here at My Pet Nutritionist, we thought we’d explore the key differences between all those biotics!  When we’re presented with prebiotics, probiotics and postbiotics, it’s hard to know where to start and if they even do a thing!‍ So let’s get cracking.‍ Prebiotics and probiotics are often thought of as one and the same, but their commonalities end with their role in the intestine. Prebiotics are fibre that feed the beneficial microorganisms residing in the intestine. Probiotics are live microorganisms that when ingested, can enhance intestinal microbial balance.‍ Why is this important? The microbiome is an important modifier of disease and an essential component of immunity.  Dysbiosis of the many microbiomes have been associated with a range of disorders.‍ Your Puppy’s Microbiome‍ What Can Cause Gut Dysbiosis‍ Your Pet’s Immune System‍ So, caring for the ecosystem found in the gut is of paramount importance.‍ Prebiotics and Gut Health The most commonly considered prebiotics are classified as soluble fibres.  They were first introduced as a functional food in 1995 by Marcel Roberfroid, but in 2007 Roberfroid clarified that only two classes of fructooligosaccharides (FOS) meet the full definition of a prebiotic. These are oligofructose and inulin.‍ Oligofructose is a 2-8–chain fructose-based saccharide molecule that undergoes fermentation in the colon, providing nourishment to the bacteria found there.‍ Inulin is a longer 9-64–chain fructose-based saccharide that is fermented more slowly, benefiting bacteria further down in the digestive system.  It can also be broken down into FOS by intestinal bacteria to provide both FOS and inulin.‍ These 2 fibres are considered minimally digestible because of the β bond–based connections of the fructose molecules.‍ It is thought that dogs and cats lack the intestinal enzyme needed to break down the β bond and so they usually break down α saccharide bonds. The resident bacteria can break the β bond, producing short-chain fatty acids (SCFAs) known as acetate, propionate, and butyrate.‍ SCFA’s have a range of roles for host health including:‍ Energy source of intestinal cells Promote gut integrity Lower colonic pH Stimulate sodium and water absorption‍ In addition, you may also find prebiotics containing the following:‍ Mannan oligosaccharides (MOS) – from the yeast Saccharomyces cerevisiae Galactooligosaccharides (GOS) – found in dairy, beans and root vegetables‍ Probiotics and Health Rather than encouraging the growth of beneficial bacteria and suppressing the growth of pathogenic bacteria, probiotics are thought to introduce beneficial bacteria into the environment.‍ It is considered that the best use for these products is treatment of GI disease, such as diarrhoea and other GI abnormalities, including inflammatory bowel disease.‍ The more we are learning about probiotic use, the more we are realising that the benefits associated are bacterial strain specific.  What this means is the devil is in the detail.‍ In addition, to function as a probiotic, the bacteria must:‍ Survive the acid and bile in the GI tract Adhere to intestinal cells or colonise areas within the tract Exclude pathogenic adherence Produce acids, or other compounds which antagonise the growth of pathogens Be safe, non-invasive, non-carcinogenic and non-pathogenic‍ The primary bacterial populations included in probiotics that have been seen to benefit both cats and dogs are lactic acid bacteria, especially lactobacilli, bifidobacteria, and enterococci.‍ Postbiotics and Health Postbiotics are the bioactive compounds that probiotic bacteria produce when they consume prebiotic fibre.‍ They are technically the waste products of probiotic bacteria and SCFA’s are one kind, along with:‍ Enzymes Cell wall fragments Metabolites like vitamins and minerals‍ Postbiotics are a relatively new concept, but they have been associated with a range of benefits:‍ Postbiotics like butyrate (SCFA) can stimulate the production of regulatory T cells in the intestine, supporting immune function Cell wall fragments can increase the production of anti-inflammatory chemical messengers known as cytokines that help reduce inflammation and modulate immune responses Increased levels of butyrate have been associated with improved clinical outcomes in inflammatory bowel disease‍ How Do We Get Them? It’s easy to reach for supplements, but certain foods already possess biotic properties.‍ Sources of Prebiotics: Mushrooms Chicory Root Garlic Asparagus Dandelion Greens Bananas‍ Sources of Probiotics: Fermented foods contain naturally occurring probiotics; but remember that prebiotics aren’t fussy about which bacteria they feed, so they could also feed harmful bacteria and yeast.  Fermented foods can also be an issue for those dogs suffering SIBO or yeast infections.‍ Bacterial Overgrowth‍ Is Your Dog a Yeasty Beast‍ Supplementation may be appropriate in certain cases, but as we have noted, benefits are often strain-specific and it’s essential to read the label fully if your dog suffers with sensitivities.‍ Does My Dog Need a Prebiotic, Probiotic or Postbiotic? We would always advocate a food first approach, so offering a fresh whole-food diet, full of variety.  But in tending to the ecosystem, which is a great modifier of disease, it’s important to not only include things of benefit, but avoid things of detriment too. The issue is when the bacteria populations in the gut get a little out of whack.‍ We need to avoid those things that can cause imbalances between the good and bad guys in the gut:‍ Overuse of antibiotics Proton pump inhibitors Antihistamines Poor motility Digestive disorders Poor pancreatic function Inflammation in the gut Stress Environmental toxins Dietary choices Poor liver function‍ What Can Cause Gut Dysbiosis‍ The inclusion of prebiotic foods is relatively easy to do, and either pre or probiotic supplementation may or may not be appropriate for your pet, but as you can see, it’s never as clear cut as we would like.‍ Luckily, here at My Pet Nutritionist we look at everything that is going on for your pet and what may be compromising their health.  Using this information, we develop a bespoke plan to get them on the right track.‍ Check out our services if you would like to know more.‍ Thanks for reading,‍ Team MPN x  

5 Mistakes Dog Owners Often Make

When we take on a dog, we make it our life mission to keep them healthy and happy; but this isn’t always easy.  In an age of information, it can get confusing what to do for the best, so here at My Pet Nutritionist, we thought we’d pop together the top 5 mistakes dog owners can make which compromises health.‍ 1) Over-Vaccinating There is no doubt that vaccination has been progressive in public health concerns, for both humans and pets, but they were never meant to make the host sick.  For a number of reasons, the current vaccinations schedule for our pets, is.‍ There is increasing evidence that over-vaccination is associated with the development or aggravation of immune-mediated disorders and chronic diseases in individual pets that are genetically predisposed.‍ This is where titre testing can be useful.‍ A titre is a simple blood test which establishes the levels of existing antibodies in the blood.  Antibodies are produced when an antigen provokes a response from the immune system.  This response can be from natural exposure or a previous vaccination.‍ A positive test indicates that the patient does have protective levels of antibodies.‍ A negative test indicates that the patient does not have protective levels of circulating antibody.  However, it is worth noting here that a negative test result does not indicate susceptibility to disease.‍ On the whole, test correlation with protection is fair to good.‍ Canine adenovirus, distemper virus and parvovirus all correlate well.‍ Feline calicivirus is fair to good, whereas herpesvirus is fair.  Feline parvovirus correlates well.‍ Findings Here‍ Titre tests are routinely used to establish the efficacy of rabies vaccination for pet travel schemes.‍ Findings Here‍ These outcomes particularly shine when you compare them to the suspected adverse reactions for vaccination in small animals.‍ Findings Here‍ Titre testing is like checking your fuel gauge before you leave home.  You want to make sure you have enough fuel to get to where you need to go.  Why not check your dog needs a vaccine before you actually give it?‍ Vaccinosis: Damage Vaccinations Can Cause Your Pet‍  2) Not Feeding A Fresh Food Diet Dogs are facultative carnivores.  This means they thrive on a meat-based diet.‍ Every cell in the body requires energy to carry out its role.  Without getting caught up in biology 101, there are a number of cycles that occur in the body to produce energy.  Dogs have this nifty ability to use this process known as gluconeogenesis – this produces glucose from non-carbohydrate sources.  Dogs have a great capacity for using fat for energy.‍ Not only do they reap the energy rewards from nutrients, but meat in it’s whole-food form contains a number of micronutrients which support body function.‍ Why Does My Dog Need Minerals‍ The issue with over-processed food is that it often becomes nutrient deplete during the process, and so, synthetic nutrients are added back in – makes a little more sense to offer them in their whole-food form in the first place doesn’t it?‍ In addition, food is only as useful as its constituents; it all needs to be digested.  Dogs have evolved on a whole-food diet for thousands of years, so their digestive system has figured out how to deal with it.  It also makes sense to feed the system something it knows how to work its magic on doesn’t it?‍ Why Dry Food Is Not Good For Your Pets‍ What Is The Best Kind Of Pet Food‍ 3) Using Toxic Chemicals in Your Home and Garden Every day, ours and our pet’s bodies are exposed to toxins.  They are produced internally in the body, like lactic acid, and consist of waste products from gut microbes, hormones, and neurotransmitters.  But the largest threat is possibly those external toxins, like air pollution, chemicals from cleaning products and volatile organic compounds from the plug-in air diffuser in your lounge.‍ It is thought that in the 25 years between 1970 and 1995, the volume of synthetic organic chemicals produced tripled from about 50 million tonnes to approximately 150 million tons, and this number has grown year on year since.‍ Findings Here‍ Data way back in 2008 reported that dogs have perfluorochemicals in their systems 2.4 times higher than humans, and cats have fire retardant particles in their systems 23.4 times higher than humans.  We can only imagine how this has panned out over recent years.‍ The Environmental Working Group found that dogs and cats are contaminated with 48 out of 70 industrial chemicals found in plastics, food packaging, heavy metals, fire retardants and stain-proofing chemicals.‍ In dogs, the findings established:‍ Contamination with 11 carcinogens Contamination with 31 chemicals toxic to reproductive health Contamination with 23 neurotoxins‍ Exposure included:‍ Dog food bag coatings House dust Stain-proofed furniture Medications/pesticides Dog beds Carpets Plastic toys Shampoos‍ Findings Here‍ Check out our other blogs on how to avoid this and also ways to help!‍ Does My Pet Need To Detox‍ Is Your Toxic Home Affecting Your Pet‍ 4) Overuse of Medications Whilst medications are lifesaving, there are often cases of overuse.‍ Antibiotics are commonly inappropriately prescribed which can have long lasting effects on the health of your dog’s gut.  Broad-spectrum antibiotics are exactly that – they take all the bugs (both the bad and the good).‍ There is also the increasing concern around antibiotic resistance; this is when a microbe becomes more or fully resistant to antimicrobials which could previously treat it.  For this reason, the EMA “is promoting the prudent use of antimicrobials in animals.” Source‍ NSAIDs are also increasingly overused.‍ During the inflammatory response, certain enzymes catalyse the production of compounds which cause pain, redness, and heat.  NSAIDs work by blocking the activity of these enzymes and so inhibit the response.‍ But these same enzymes, like many in the body don’t just carry out that role.  They are also protective of the stomach mucosa for example, which means when you take out that enzyme, you also take out a layer of mucosal protection!  This is why chronic

Why Is My Dog Itchy?

We sometimes talk about intolerances and allergies like this is the only thing that can cause your cat or dog’s itching. There can be so many reasons, layered reasons and some more serious than others.‍ Here we explore some of the undetected and misdiagnosed reasons for your dog being itchy.‍ Adrenal function The adrenal glands are located just in front of the kidneys.  You will recognise them from when we discuss the stress response more often than not.‍ The adrenal gland has 2 parts—the cortex and the medulla.‍ The adrenal cortex is subdivided into 3 layers, and each layer produces a different set of steroid hormones. The outer layer produces the mineralocorticoids, which help regulate sodium and potassium salts. The middle layer produces glucocorticoids, which are involved in metabolising nutrients and reducing inflammation and immune responses.  Finally, the inner layer produces sex hormones such as oestrogen, progesterone, and androgens.‍ The adrenal medulla plays an important role in response to stress or low blood sugar levels in the body.  It releases adrenaline and noradrenaline, both of which increase heart rate and blood pressure, increase blood sugar and slow digestion; the hallmark responses when us or our dogs are exposed to a stress trigger.‍ The adrenal glands are part of the endocrine system – which is simply a system of glands that release chemical messengers called hormones.  The endocrine system influences almost every cell, organ, and function in the body.‍ So, if there is any issue in any part of it, things can start to go wrong.‍ The two most common ways in which adrenal glands cause health issues are by producing too little or too much of certain hormones, which leads to hormonal imbalances.‍ Hyperadrenocorticism (Cushing’s Disease) due to an excess of cortisol production frequently causes dogs to itch, lose hair, have thin skin with dark pigment, drink excessively and have recurring skin problems.‍ But this raises another point, even if there are no physiological issues with the adrenal glands, high cortisol levels due to daily stress can also lead to itchy skin!‍ Thyroid Function We’ll continue with the hormones for a minute and look at thyroid function.‍ The thyroid is a butterfly shaped gland found in the neck.  One of its main functions is to produce hormones to regulate the body’s metabolism, the process that turns food into energy.‍ This too can produce too many hormones, or too few.  These conditions are known as hyperthyroidism and hypothyroidism respectively.‍ Hypothyroidism‍ Hyperthyroidism‍ Hyperthyroidism in Cats‍ Skin issues are regularly noted in times of thyroid dysfunction, and this includes itchiness.‍ Kidney Function Intense itchiness often accompanies late-stage kidney disease, and whilst the jury is out on the exact reasons behind it, it is thought that it’s relating to the build up of toxins in the body.‍ This leads us nicely into the same itchy symptoms associated with early-stage liver disease, and this is considered for similar reasons.‍ Detoxification Detoxification is carried out by a range of mechanisms, and this comes in particularly handy if one pathway is overwhelmed, another can pick up the slack.‍ The Liver The liver neutralises a range of toxic chemicals, both those produced internally (waste from used hormones or neurotransmitters for example) and those from the environment, like air pollution, pesticides, and food additives.‍ It does this by filtering the blood to remove large toxins, synthesising, and secreting bile and lastly enzymatically disassembling unwanted chemicals found in the body.‍ Liver Guard ‍ Enzymatic Detoxification This enzymatical detoxification occurs ‍in three phases.‍ Phase I directly neutralises chemicals and changes them into new metabolites.  These are then processed by phase II enzymes.  This is known as the conjugation phase, which in short, liver enzymes attach small chemicals to the toxin.  There are many ways in which this is done, it all depends on the type of chemical the liver is trying to manage.‍ Phase I results in high levels of reactive oxygen species so antioxidant levels are key in modulating potential damage.‍ Phase II is nutrient demanding and sufficient levels of key vitamins and minerals like vitamin A, C, E, B1, B2, B3 and iron are essential.‍ Phase III is the elimination phase. For optimal excretion of toxins through the digestive system, gut health is vitally important.  Maintaining the mucosal barrier is key for gut health along with supporting motility.‍ The kidneys will also filter and process toxins from circulation, excreting them as urine.‍ The skin also forms as an elimination pathway.  This is why detoxification issues can result in skin issues.  In cases of liver disease, it is considered that bile salt deposits under the skin, which results in itchiness.‍ The most important thing to do to support detoxification is to avoid exposure in the first place, so consider how much you and your dog are exposed to:‍ Pesticides Heavy smoke Phthalates Mould Medications like steroids, antibiotics, and painkillers Heavy metals Cleaning products Air fresheners Eating foods cooked at high temperatures (most commercial dry foods)‍ This list is not exhaustive, but it is a place to start.‍ This mechanism also applies to vaccines.‍ There is increasing evidence that over-vaccination is associated with the development or aggravation of immune-mediated disorders and chronic diseases in individual pets that are genetically predisposed.‍ The primary role of the immune system in dogs is to protect against foreign invaders, or abnormal cells that invade or attack.  The immune system must distinguish between self and non-self.  Substances that stimulate a response are antigens.  These can be contained within bacteria, viruses or microorganisms or cancer cells.  They may also exist on their own, like pollen or food particles.  There are three lines of defence, physical barriers, nonspecific immunity, and specific immunity.‍ But the immune system does not always function properly, it can be underactive and overactive.  An underactive system puts the animal at risk of infection, but an overactive immune system can attack parts of its body that it misidentifies as being foreign.  This is what happens in autoimmune conditions.  The immune system can also overreact

5 Tips For Anxiety in Dogs

Sadly, anxiety is as common in dogs as it is in humans.  Anxiety is the body’s normal response to stress; the problem is that our stress response hasn’t evolved with modern life and both us and our dogs often feel overwhelmed.‍ A stressful situation can bring about a whole cascade of biological responses and it all starts in the brain.‍ When someone confronts an oncoming danger, the eyes or ears, or both (and parts of the peripheral nervous system) send the information to the amygdala, which is the area of the brain that deals with emotions. The amygdala interprets the images and sounds and sends a message to the hypothalamus.‍ The hypothalamus is like the command centre. It communicates with the rest of the body through the autonomic nervous system, which controls such involuntary body functions like breathing, blood pressure and heartbeat.  It also controls the dilation or constriction of key blood vessels and small airways in the lungs called bronchioles.‍ The autonomic nervous system is further split into two branches, the sympathetic nervous system and the parasympathetic nervous system.‍ The sympathetic nervous system functions like a gas pedal in a car and it triggers the fight-or-flight response.‍ The parasympathetic nervous system is like the brake pedal; it slows everything back down and returns the body to homeostasis, or as we know it, rest and digest.‍ In cases of anxiety, the sympathetic nervous system remains activated, it’s a form of chronic stress.‍ So, when tackling anxiety, we need to take the paw off the gas pedal, and firmly place it on the brake.  It goes without saying that removing the trigger that causes the stress or anxiety is of paramount importance, but in many cases, like on bonfire night, we can’t remove it in its entirety.  In cases of separation anxiety too, we often want to take the edge off the response in order to work through a behavioural programme.‍ 1) Thunder Jackets These jackets work under the premise that applied pressure calms nervous system function and many owners report success.‍ A study in the Journal of Veterinary Behaviour explored a range of methods for managing firework fear in dogs with the following efficacy:‍ Pressure jackets 44% Counterconditioning 70% Relaxation training 69% Noise CDs 55%‍ 2) Chamomile Chamomile (Matricaria recutita) is one of the most widely used herbal remedies in the world.  While there are many varieties of chamomile, Roman (A. nobilis) and German (M. recutita) are the most widely used forms. These are members of the Compositae (Asteracae) family.‍ German chamomile is considered the more potent and is most widely used. It has many medicinal uses including carminative (anti-colic), antiseptic, and anxiolytic.‍ Chamomile is notorious for its continuous bloom!‍ Chamomile serves as a safe, general purpose calming herb that doesn’t taste too shabby either.  In human tests it has been effective in mild to moderate generalized anxiety disorder.‍ Findings Here‍ It can be served as a tea, but is also available as an oil infusion, tincture, salve and ointment.‍ 3) Valerian Many will recognise valerian for its similar smell to old, dirty socks!‍ Valerian (Valeriana officinalis) is commonly used for the treatment of insomnia and anxiety disorders in humans.  It has a mechanism of action similar to benzodiazepines; however, instead of binding to the gamma subunit like a benzodiazepine, it appears to bind to the beta subunit on the GABA-A receptor instead.  Regardless, it has the same effect on chloride movement into the neuron when the major inhibitory neurotransmitter, GABA, binds to the GABA-A receptor, thereby causing a hyperpolarized state.‍ In addition, valerian has also been shown to decrease the removal or metabolism of GABA, thereby allowing GABA to stay around longer and do it’s thing.‍ And as we know, GABA is the brake like neurotransmitter in the body.‍ Findings Here‍ Valerian is available in tincture, tea and fresh or dried root.‍ 4) Skullcap Another herb used for insomnia in humans, it has a similar mechanism of action to Valerian.  Skullcap too is thought to be GABAergic.  But it is also thought to have an effect on serotonin receptors, which is why it has reported sedative and relaxing effects.‍ A small, placebo-controlled, double-blind, crossover study of 43 human participants demonstrated that skullcap reduced symptoms of anxiety and depression in some individuals without causing an observable reduction in energy or cognition.‍ In both cats and dogs, skullcap has been effective in generous nervousness and excitability and in any condition where there is oversensitivity in the nervous system.‍ Skullcap is usually found in dried herb or tincture form.‍ 5) St John’s Wort St. John’s Wort (Hypericum perforatum) is an herbal medication that consists of anthraquinones, which have displayed anti-inflammatory and anti-cancer effects. It has also been used as an antidepressant in humans. It derives from a flowering plant found in Europe and Asia. It is usually found in capsule, tea, or liquid extract.‍ It is thought that St. John’s Wort acts as a serotonin reuptake inhibitor. This works to reduce the uptake of serotonin at neuronal synapses, as well as dopamine and norepinephrine.‍ One of the primary adverse effects is the risk of an increase in serotonin when combined with certain antidepressants and the inhibition of monoamine oxidase. Be cautious of signs including tachycardia, increased blood pressure and mydriasis.  There may also be a fever.‍ It is however, often used in dogs with fear-based or separation anxiety. ‍ A great product for anxiety is our Calming Complex Calm Complex ‍ The introduction of any new supplement or herb is always done best under the guidance of a practitioner.‍ If your dog suffers with anxiety, it’s crucial to work within a behaviour programme to tackle key triggers.  However, there can also be a multi-modal approach and our services may be of use.‍ Please take a look under our “what we offer” tab!‍ Thanks for reading,‍ Team MPN x