Whether you are purchasing for your own pet, or for a friend or family member, buying pet products, just like food, can be a bit of a minefield. When more and more of us are trying to live sustainably, can we do this with our pets too? We’ve popped together some things to consider before you buy that next toy, chew, grooming product or bed! The Problem with Plastic It’s clear that the majority of pet products on the market are unfortunately made from plastic. Not only have we got the global issue of too much single use plastic, but it is actually harmful to health (yes, that includes our canine companions too)! A common chemical used in the production of plastic is bisphenol A, also known as BPA. We’re sure you’ve heard of it. Studies have shown that BPA affects the reproductive systems of laboratory animals suggesting it disrupts hormones, and many more body functions. Not only that but you will often find phthalates in plastic toys too. These are what makes the toy more flexible and durable. These too are known as endocrine disruptors. We know that plastic doesn’t break down (you only have to look at the poop of a post-toy-assassination) so when your dog has gotten bored of that particular toy, you’ll dispose of it, but it can’t be recycled, so it will just end up in landfill for hundreds of years! If you are looking to raise a plastic free pooch, it’s not as hard as you think. Opt for toys made out of natural materials like cotton, rope, canvas, wood, wool or bamboo. You can even make your own out of old T-shirts or towels (reusing and recycling is much better for the environment). The other thing to check when you purchase, is how durable the product is. You want to make sure it is safe; that it doesn’t have small parts that can be chewed and swallowed. Squeak toys are the worst! Dogs instinctively want to get to the squeaker, but it’s easily swallowed and can cause an obstruction. You want an item to last, so if your dog is a toy-assassin, then it’s just a waste of money buying one you know will be killed in a matter of seconds! Whilst toys are often gifts of choice, chews and treats are firm contenders too! But this can be even more of a minefield for dog owners! It pays to look at the labels of chews or treats. You need to recognise the ingredients listed. Ideally, the first ingredient should be a meat protein. View chews and treats like you would when searching for a new dog food. Whilst it’s a complementary addition to their diet, it still needs to be beneficial to their health! Look at where it is made and source as local as possible. If you are raising a plastic free pet, then opt for packaging that is totally recyclable or biodegradable too. If you choose natural chews, they often don’t even need packaging! If you are considering buying grooming products for your pet or family member pets, again reduce plastic where possible. Shampoo bars are becoming increasingly popular. They are often cruelty free and do not contain parabens, phthalates or sulfates. Most shampoo bars come in paper packaging which is 100% recyclable. Choose brushes with natural bristles and wooden handles. Perhaps bedding or blankets are your next purchases? Choose items that are machine washable, so you can keep them for a longer period of time as opposed to disposing of them when they get too dirty! When you are washing them, pop them in a guppybag. This acts as a microfilter, stopping tiny plastic particles from getting into the water system. This is especially important for fleecy items as they are made from plastic (albeit recycled). Whilst you may be trying your best to buy safely and sustainably, it can become an issue when friends or family buy for your pet. Many of us have accepted gifts knowing they will just end up in the bin. This is sad for a number of reasons. The sale has already taken place, so there has been indication of demand and secondly, it’s another item in landfill. Consider setting up a wish list for your pooch, with safe and sustainable items on. Or, start buying these products for friends and family and explain why you are so excited about them. Hopefully, they’ll too see the benefits and pass them on the next time they buy a gift. As Bernadette Jiwa suggested “…in a world where it’s easy to be cheaper and faster than the competition, we now recognise the limitations…humans are wired to do what feels good and what feels good to customers right now is to use their choices and purchasing power to support the building of a better tomorrow.” Thanks for reading, MPN Team
Would you be surprised to know that the skin has developed its own local HPA axis to regulate its exposure to stressors? Recent mapping has found that all regulatory elements found in the central HPA axis are expressed in skin! Could this explain why skin issues tend to worsen when us humans are stressed? More importantly, when skin issues are the top issue facing the majority of dog owners we see here at My Pet Nutritionist, is this something we need to consider? The short answer is yes. So, let us take a deeper dive at what the HPA axis is and how this can influence our pet’s skin issues. The HPA Axis Most of us have heard at one time or another the mention of the HPA axis when we talk about the stress response. It stands for hypothalamic-pituitary-adrenal axis. In short, the hypothalamus in the brain receives a message that we are being exposed to a stressor, it then sends a message to the pituitary gland which then sends another message to the adrenal glands. It is the adrenal glands that release the hormones we typically associate with stress, like cortisol and adrenaline/noradrenaline. These stress hormones flood the body, and help it deal with whatever the stressor may be – and then when it has passed, the hormones stop being produced; the body then returns to homeostasis. This exact response also occurs in our pets when faced with a stressful situation, and so our pets too have a HPA axis. Now we know what the HPA axis does, let’s see how the skin has developed its own local axis. The Skin’s HPA Axis The skin is the largest organ of your dog’s body. It consists of three major layers: The Epidermis – (Epi – upon or above) this is the outer layer of skin, the protective layer. The Dermis – the dermis supports and nourishes the outer layer. It provides strength and elasticity. Here you will find collagen fibres, sweat glands, sebaceous glands, and hair follicles. You will also find cells that release histamine and other inflammatory mediators when faced with an allergy or injury. The Subcutis – (sub meaning under or below) this in the innermost layer of the skin, where you will find fat and muscles. Subcutaneous fat provides insulation, padding and storage for reserve energy. Not only does the structure of the skin prevent water and electrolyte loss to help maintain body homeostasis, but it forms a protective barrier which helps protect against infections, parasites, and the environment. This is the often-forgotten role of the skin – that it forms part of the immune system. When we think of the skin as the first layer of defence in the immune system, and therefore a type of radar, it makes absolute sense that it should have its own response to stress. It seems that skin cells, known as keratinocytes, can produce the same hormones and neurotransmitters that the “internal” stress response does. These include: corticotropin-releasing-hormone (CRH) cortisol adrenaline noradrenaline dopamine histamine acetylcholine All of these compounds help the body deal with a stressor, they include increasing heart rate, upregulating energy conversion and redirecting resources to those functions that are necessary. So, the skin, we can think of like a radar. It constantly senses the environment and reacts to various stressors like humidity, temperature, changes in the skin microbiome and of course injuries. CRH is possibly the most studied hormone and in the skin, it is involved in the proinflammatory response. When exposed to a stressor, CRH brings an inflammatory response to help manage the threat. If your dog scratched himself, the inflammatory response would be a normal part of healing. However, a natural by-product of this process is that it increases skin permeability which isn’t great long term. The skin serves as a protective barrier and if it becomes permeable, harmful compounds can sneak in, which can cause further problems around the body. Acute Vs. Chronic Stress Like everything, moderation is key – acute stress is manageable, the issue is when it becomes chronic. Where this becomes even more problematic is that animal studies have suggested that skin stress can initiate a central HPA axis response. When researchers exposed rodents to UVB radiation, they found increased stress responses in the adrenal glands. So, not only can the skin respond directly to a stressor, but it can bring the central response to the party too! What this means is that skin stress can cause body wide stress, and again this becomes an issue in chronic skin issues – leading to chronic activation of the “internal” stress response. To add insult to injury, psychological stress increases the production of “internal” stress hormones which then affects skin cell growth and function, compromising structure and altering skin permeability. So not only can skin stress cause psychological stress, but psychological stress can cause skin stress. You can see how this can become a challenging cycle to break. But what we must remember is that most functions in the body serve a necessary function and this mechanism (although challenging) is no different. HPA Axis and Skin Barrier The HPA axis in the skin responds to various stressors to regulate homeostasis – it serves to counteract any threat so normal function can resume. The compounds produced and released all serve important roles in maintaining a healthy skin barrier. ACTH (adrenocorticotropic hormone) is involved in melanin production which protects the skin from ultraviolet radiation. In dogs, it is melanin that contributes to skin and hair colour. In autoimmune conditions, melanocytes can be destroyed which results in depigmentation. This is also why if you have a dog who has repeated skin trauma (scratching etc) they develop visibly darker skin in those areas. Keratinocytes with more melanin display superior barrier function – which is why the body attempts to achieve it in repeated trauma. Endorphins are also released during skin stress. This enhances epidermal turnover rate, again to protect skin function. This could be why
Time and time again we see that our pets are contaminated with a range of chemicals and toxins, but recent data indicates that they boast even higher levels of contamination than us humans. Let’s take a look at the data and see how we can reduce contamination. How Contaminated Are Our Pets? In a recent study, dogs and cats were contaminated with 48 of 70 industrial chemicals tested, including 43 chemicals at levels higher than those typically found in people. The chemicals included: plastics and food packaging chemicals heavy metals fire retardants stain-proofing chemicals Average levels of many chemicals were substantially higher in pets than people, with 2.4 times higher levels of stain- and grease-proof coatings (perfluorochemicals) in dogs, 23 times more fire retardants (PBDEs) in cats, and more than 5 times the amounts of mercury. Dog Contamination Blood and urine samples have shown contamination with a range of chemicals, including 11 carcinogens, 31 chemicals toxic to the reproductive system, and 24 neurotoxins. Cat Contamination Cat samples contained 46 chemicals altogether, including 9 carcinogens, 40 chemicals toxic to the reproductive system, 34 neurotoxins, and 15 chemicals toxic to the endocrine system. Endocrine system toxins raise particular concerns for cats, since they include the thyroid toxins and fire retardants, PBDEs. Thyroid disease (hyperthyroidism) is a leading cause of illness in older cats and it is regularly linked to fire retardant exposure. Hyperthyroidism in Cats Let’s look into individual exposure in a little more detail and some evidence backed links to certain health issues. Potential Exposures: – A dog eating scraps from the floor may swallow dirt and dust tracked in from the outdoors and contaminated with heavy metals and pesticides. – Dogs and cats often eat food processing and packaging chemicals that contaminate their food, day after day and year after year, resulting in cumulative exposures. – Chew toys might contain plastic softeners. – Foam beds might be infused or coated with fire retardants and stain-proofing chemicals. – Plastic water bowls might leach hormone disruptors. Evidenced Links to Health Issues: – “Teflon toxicosis” has been the cause of death for hundreds of pet birds nationwide whose lungs filled with blood after they breathed in toxic fumes from overheated, non-stick pans – what may this be doing to our pets? – Studies show bladder cancer at a higher rate in dogs living near industrial areas or if their owners use lawn and garden weed killers and insecticides. – In addition, in a case-control study of bladder cancer in household dogs, the cancer risk was significantly increased by the use of topical insecticides. For 1-2 topical applications per year, bladder cancer risk was increased by 1.6 times, whilst more than 2 applications per year the risk was 3.5 times greater. – Lead toxicosis has been found in dogs and cats in homes with chipping lead-based house paint. – Malignant lymphomas are found in dogs whose owners use certain lawn pesticides. – Mouth cancer (oral squamous cell carcinoma) has been found in cats exposed to certain flea repellents. We must also consider the foods that we are feeding our pets. A massive recall was initiated in March 2007 after many pets became sick or died after eating certain brands of pet foods. Poisonings of pets were traced to the presence of melamine and cyanuric acid in imported wheat gluten that was used for pet food production. Findings Here According to the Environmental Working Group: “These events highlight the vulnerability of pets and their owners who, due to insufficient government oversight over chemicals present in pet food, are left to trust that the pet food industry will regulate itself.” The list of potential contaminants is endless, which can leave us a little disheartened as pet owners. But, information is power, and if we know what could be compromising our pet’s health, we can take steps to mitigate the damage. We can limit exposure to contaminants as much as possible by opting for a low-tox lifestyle. What does a low-tox lifestyle look like? Plates instead of plastic bowls Non-toxic grooming products Steam mops White vinegar and baking soda for cleaning Wooden floors or tiles with washable rugs instead of carpets Natural flea and worm options Fresh food diet Filtered water Natural garden care and insect repellents Air purifiers – machines or bamboo charcoal bags Safe plants (for both cats and dogs) The thing to remember is that many of us have become accustomed to sweet smelling homes, but all we really need is a clean home. Wash rugs, blankets and beds frequently (in white vinegar to keep wet dog smells at bay) and if you have guests coming over, pop a vase of (safe) flowers on the table. We regularly see how a high-tox lifestyle has compromised pet skin health, along with their gut and liver function. And as we can see from the evidence, contaminants are implicated in many more health issues in our pets. If you would like any support in optimising your pet’s health, then please check out our services to see how we can help. Thanks for reading, MPN Team
Whether it’s a trail of slobber across your face or you’re sitting in wonder at your dog licking the slate around the fireplace, dogs like to lick. Everything. We find it endearing and a sign of affection when we get a tongue to the ear, or we just assume they’re practicing good hygiene when they are licking their paws. More often than not, only your dog knows why they are licking that rock in the garden. But there are occasions when there is more to licking behaviour. Let’s delve into the world of allergies, stress, pain and just good old-fashioned grooming. Why do dogs lick their paws? If you made a tally of a day in the life of your dog, licking paws would come in pretty high. More often than not, dogs will lick their paws to groom themselves. So, if they’ve come in from their walk or even just from a mooch around the garden, you’ll find them preening themselves and even having a little nibble. This is generally expected behaviour. However, this can become excessive if your dog is irritated by something they walk through or on. Grasses, pollens and toxic chemicals can all cause irritation to their sensitive paws. You also run the risk of salt or antifreeze exposure during extreme weather. Not only does this irritate them externally, but through grooming, they ingest it and can cause subsequent damage internally. It’s always best to rinse your dog’s paws when returning from a walk and give them a towel dry. In extreme climates you can even apply an all-natural paw balm or simply some coconut oil. Dogs will also lick parts of their body that are painful or stiff; so, if your dog has strained or sprained their leg, they may start licking their paw of the affected leg. Long nails can cause pain too, so check your dog thoroughly if the licking is a new behaviour. Dogs In Pain Excessive licking is usually identified by a reddening of the hair on the area being licked, so it’s pretty easy to notice. This is thanks to a protein found in the saliva which stains the hair. It’s not blood, don’t worry. However, excessive licking can cause trauma to the hair and skin, leaving inflamed, red and sore patches. This is why the underlying issue needs to be tackled as soon as possible. Why do dogs lick people? Some dogs lick people, some dogs don’t. How they have been raised plays a huge part in this. Quite often, if a dog has been allowed to lick their owner, they may lick other humans. If, however, an owner doesn’t want this behaviour, then they will ignore it. The dog won’t get a response and often will cease to do it. Those of us crazy dog owners who couldn’t care less whose canine slobber we get covered in, usually become jovial, we smile or laugh. The dog, even in the absence of a “food” reward, is receiving positive reinforcement. Dogs can read human emotion and, maybe, if they think we like being licked, they figure it’s just something they should keep doing. Why do dogs lick faces? It’s impossible to know for certain why dogs like our faces, but we think it comes from their puppyhood. If you notice how Mum Dogs behave with their puppies, they spend a huge time licking them, grooming them. The great thing is, the more a Mum Dog does this, the more resilient her puppy is as they grow. They are also less reactive to stress. It is believed that this behaviour reduces the amount of stress hormones in the puppy’s body. So, we could argue that our dog licks our face because they are imitating the behaviour they experienced. We could also argue that our dogs do it to help soothe us (do they do it more if we are stressed?) The less endearing explanation is that actually, as a dog’s sense of smell is so great, they’ve sniffed out a crumb or remnant of food/drink around our mouths and actually just want a taste. Why do dogs lick your feet? Most will agree, feet are the smelliest part of the human body. In terms of biology, this is pretty accurate. Human feet have more sweat glands per inch than anywhere else on the body. Wearing tight fitting socks and shoes also keeps moisture and heat in, providing a great environment for bacteria to multiply. Dogs have a great sense of smell, so when there could potentially be a great mixture of water, ammonia, potassium, nicotinic acid, magnesium, chloride, sodium, creatinine, uric acid, ascorbic acid, thiamine and riboflavin (also known as sweat) and then a whole host of different bacteria, why wouldn’t your dog have a lick and see what they could find? Dog’s explore their world through smell and sight. Maybe they’re just drawn to the smelliest part of the human body? (we’re not saying you have smelly feet, they can just find more information there). Why do dogs lick the air? Whilst dogs do explore their world through smell, and smell contributes massively to taste experience, it’s unlikely that when your dog is licking the air, they are trying to “taste” the air. They are more likely, stressed. Licking is a stress behaviour for canines. Notice when your dog is licking the air; what is happening in their environment. Is someone touching them? Has someone new come into the home? Are you near their food? Is someone near their toy? Are kids nearby? Have you made a fuss and touched a certain part of their body? This could indicate pain. It’s important to notice the trigger and also watch for other stress behaviours like; drooling, panting, yawning, pacing, head flicking or turning away from the stressor/trigger. Find the trigger and remove it. Licking is a warning signal; ignorance often leads to escalation. Why do dogs lick their nose? Like we mentioned above, this is most likely a sign of
Sadly, there are a colossal number of dogs that suffer with their skin, whether seasonal, or 365 days of the year. So, what on earth is going on? Let’s take a look at the skin in a little more detail, what it is, what its function is and what can go wrong. The skin is actually the largest organ of your dog’s body. It consists of three major layers: The Epidermis – this is the outer layer of skin, the protective layer. The Dermis – this layer supports and nourishes the outer layer. It provides strength and elasticity. Here you will find collagen fibres, sweat glands, sebaceous glands, and hair follicles. Here you will find cells and compounds involved in inflammatory response and therefore allergies. The Subcutis –this in the innermost layer of the skin, here you will find fat and muscles. Subcutaneous fat provides insulation, padding and storage for reserve energy. Not only does the structure of the skin prevent water and electrolyte loss to help maintain body homeostasis, but it forms a protective barrier which helps protect against infections, parasites, and the elements. In dogs, their hair also forms a barrier, therefore hair health is synonymous with skin health, and a dog’s coat type can actually influence skin status. Could My Dog’s Coat Type Contribute to Skin Issues? This protective barrier in fact forms part of the immune system. It is the first line of defence. It does this in two ways: – Through its physical structure – Through its microbiome Gut Guardian The Physical Structure As we have noted, the skin has three layers. Keratinocytes are produced in stem cells and they push their way up through the layers; being smothered in lipids as they go. When they reach the epidermis, they harden and form a tight structure. These eventually shed, and new cells make their way up. Issues arise when this tight structure becomes fragile. We can think of it in a similar thread to leaky gut. What Is The Gut Barrier? In cases of leaky gut, it becomes permeable to larger proteins or pathogens. In short, things from the gut get to places they shouldn’t really be. In leaky skin, the tight structure hasn’t formed, and so potentially harmful compounds can get through the skin layers and go to places they shouldn’t be either. When ours, or our dog’s immune system senses non-self-compounds (those that have gotten through its first line of defence), it mounts an inflammatory response resulting in swelling, itching, pain and so on. If we consider the itchy dog, they gnaw at their paws because they are itchy, this then compromises the skin structure causing further inflammation and so the cycle continues. The other way in which the skin serves to protect is through its microbiome. Not surprisingly when there is dysbiosis in the microbiome of the skin, conditions like atopic dermatitis often ensue. Dysbiosis simply means out of balance. There are good bugs, and bad bugs, and the aim is to keep them in balance. Tackling Atopic Dermatitis In Pets We know that in the canine, there are different species found on different areas of the skin. We also know that the populations found differ between allergic and healthy dogs and that lower diversity is often observed in recurring skin issues in the canine. So, what affects the diversity in the skin microbiome? Colonisation occurs during and immediately after birth. As the newborn puppy moves through the birth canal, he is exposed to a variety of bacteria from the Dam. Once puppy is born and grooming begins, Mum passes even more over to her offspring. What is important to note is that grooming behaviour is significantly reduced in the stressed Mother, and so less microbes are therefore shared with the offspring. This again demonstrates the need to fully research where you have your puppy from. In humans it is thought that the microbiome stabilises somewhat in the first 2-3 years of life, but there isn’t yet a clear answer on this time frame in the canine world. Given the development of a puppy compared to a human child, we can say for certain that those first few months of life are incredibly important. There is also a clear distinction between male and female microbiome, therefore suggesting hormonal influences. This poses food for thought in the neutered pet and how their microbiome is subsequently affected. The environment has a huge impact on the microbiome of the skin. There are noted variations in skin microbial communities between those living rurally and those in urban areas. There is also an increase in chemical use associated with urban living, which also influences the composition of the microbiome. Diversity is significantly reduced with the use of detergents and antibacterial cleaning products. Potentially pathogenic taxa is also increased as there are fewer good guys to keep the bad guys in check. This is why skin issues like acne or dermatitis are deemed western diseases; they simply just aren’t found on the skin of indigenous tribes or on that of individuals from non-industrialised societies. Findings Here Unnecessary use of antibiotics also affects the microbiome, along with excessive use of grooming products and of course nutrition. Does My Dog Have a Gut-Skin Axis? Skin Dysfunction When the physical barrier is broken, non-self-compounds can invade the body, kick-starting an inflammatory response. This results in redness, swelling and so on. These can be pathogens, but they can also be irritants. These irritants need to be managed by the body, but in some cases the burden can be too high and so the body remains in a state of chronic inflammation. This is why removing environmental exposure to toxins is so important in managing skin issues. Does My Pet Need To Detox? Skin issues often go hand in hand with food sensitivities, and so an elimination diet here is essential. Elimination Diets For Dogs But skin issues can also be a result of pain. Some dogs will nibble and chew at
If you have followed us here at My Pet Nutritionist for any length of time, you’ll know that we’re great advocates for the inclusion of veggies for their prebiotic and fibrous benefits. But there are also times where we would avoid certain veggies. Keen to learn more? Read on. Nightshade Vegetables and Arthritis Some believe that the solanine contained in nightshade vegetables like bell peppers, tomatoes and potatoes may increase levels of inflammation in the body. Whilst there is disagreement over the mechanism, humans suffering with arthritis often report a worsening of symptoms after eating nightshade vegetables. There is one school of thought that it could be more to do with a sensitivity to the food, which results in an inflammatory response, contributing body wide circulating cytokines. Whilst nightshade veggies are a great source of certain nutrients, there are other foods which can provide these and so if you notice a worsening of arthritic symptoms, it’s an easy change to make. Natural Arthritis Guide Lectins and Should My Dog Eat Them? Goitrogenic/Cruciferous Veggies in Thyroid Issues The thyroid gland produces three important metabolic hormones, thyroxine, triiodothyronine, and calcitonin. Thyroid stimulating hormone (TSH) produced by the anterior pituitary gland controls the production of these hormones. Iodine, derived mainly from sea-foods or consumed in the form of iodised salt, is utilised for producing T3 and T4 hormones. T3 and T4 hormones affect every cell and organ in the body. They regulate the rate at which the body uses energy, which subsequently affects weight loss or gain. They raise or lower body temperature. These hormones influence the speed at which food moves through the digestive system. They affect brain development and also control the way muscles contract. Common thyroid disorders in our pets include hypothyroidism and hyperthyroidism, meaning the thyroid is either under-active or overactive. Ultimate Guide: Hyperthyroidism Ultimate Guide: Hypothyroidism Goitrogens are plant chemicals that can decrease the production or activation of thyroid hormone, meaning they slow thyroid function. These foods are commonly known as goitrogenic, which means they contain substances which slow the thyroid’s ability to uptake iodine. If eaten in excess, these foods interfere with the efficient function of the thyroid gland. The strongest goitrogens are soy products, but moderate inhibitors include: Broccoli Cabbage Kale Cauliflower Brussels sprouts All/Starchy Veggies in Yeast Issues Around 150 strains of yeast are thought to utilise starch as a sole carbon source for aerobic growth. In short what this means is starch is food for yeast! Starch, or amylum, is a complex carbohydrate that exists in many foods, including grains, vegetables, and fruits. Sources of starch are primarily: Maize Tapioca Wheat Potatoes The extraction of pure starch from food produces a white, tasteless, and odourless powder that doesn’t dissolve in cold water or alcohol. Starch is a natural polymer, or polysaccharide, meaning that it is a long chain comprising one type of molecule. Starch consists of glucose molecules. It can occur in two forms: amylose and amylopectin. You may be familiar with this wording as amylase is a digestive enzyme which helps break down starch. Yeast or candida is an opportunistic fungal pathogen but a normal part of the gastrointestinal flora and genital tracts. The issue is when there’s an overgrowth. If we are tackling an overgrowth, the last thing we want to do it continue feeding it and as you’ve now realised, starch is a great food source for yeast! Is Your Dog A Yeasty Beasty? All Veggies in the Case of An Elimination Diet When we are supporting a dog with digestive issues, we need to know exactly what is contributing to their symptoms. For this reason, we would avoid feeding all vegetables when running an elimination diet. Just like a dog can have a sensitivity to a certain meat type like chicken or beef, they can also have a sensitivity to fruits and vegetables. It’s important to remember that an elimination diet is a diagnostic tool – not a long-term lifestyle and in some cases, a means to give the immune system a welcomed break. In running an elimination diet, we follow the 4 R’s. – Remove – remove offending foods, one at a time and note changes in symptoms. Quite often, even offending foods can be reintroduced at a later stage. – Repair – support immunity and gut healing with ingredients like slippery elm, de-glycerised liquorice, glutamine, and N-acetyl-glucosamine. It is also important to consider how existing medications are affecting gut healing for example, steroid use impairs intestinal absorption which is linked to several gastrointestinal dysfunctions. – Restore – as the microbiome is key in the development of the immune system, supporting this is essential, however, the introduction of specific pre and probiotic foods is often best left whilst we get to the root cause. – Replenish – indigestibility of food proteins can also contribute to their antigenic nature, so consider any long-term medication use including proton pump inhibitors which affect gastric acid secretion. Ensuring HCL, pepsin and digestive enzymes are in good supply will help get the digestive system back to doing what it does best! Elimination Diets For Dogs We can’t deny the fibrous benefits of many vegetables along with their nutrient content, but when we are tackling a specific health issue in a pet, we must prioritise. We can often get those benefits in other ways if we think outside of the box. If you would like any support with your pet’s health and some outside of the box thinking, then please check our services to see how we can help. Thanks for reading, MPN Team
Whilst we get skin issues across the board in dogs; we can’t deny that certain breeds are more predisposed than others. But if we have a list in our mind of those dogs who we think are more likely to suffer, have we even considered that their coat type may play a role? We’re going to take a look at those double coated breeds specifically, and why they may suffer with skin challenges. The Canine Coat When we are discussing the canine coat, we include both the skin and hair/fur. Both have their own individual functions, and both are crucial to your dog’s ability to thrive. The skin is the largest organ of your dog’s body. It consists of three major layers: The Epidermis – (Epi – upon or above) this is the outer layer of skin, the protective layer. The Dermis – the dermis supports and nourishes the outer layer. It provides strength and elasticity. Here you will find collagen fibres, sweat glands, sebaceous glands, and hair follicles. You will also find cells that release histamine and other inflammatory mediators when faced with an allergy or injury. The Subcutis – (sub meaning under or below) this is the innermost layer of the skin, where you will find fat and muscles. Subcutaneous fat provides insulation, padding and storage for reserve energy. Not only does the structure of the skin prevent water and electrolyte loss to help maintain body homeostasis, but it forms a protective barrier which helps protect against infections, parasites, and the elements. The hair sprouting from the follicles in the skin, known as hair or fur, also protects against harsh weathers, temperatures, and ultraviolet light damage. Double coats are generally termed fur and single coats are generally termed hair. Although, most owners, and groomers for that matter, use the phrases interchangeably. Double Coats vs. Single Coats Dogs can have primary and secondary hairs. Primary hairs are single hairs that grow from a follicle. If present, secondary hairs exit from the same follicle and you can have anywhere from 3-15 of them exiting alongside a primary hair from the same follicle. Primary hairs are often referred to as guard hairs or the outer coat and secondary hairs are referred to as the undercoat. Double coated breeds have both primary and secondary hairs, like the German Shepherd, Alaskan Malamute, Husky and Akita whereas single coated breeds simply have primary hairs, which include breeds like the Poodle or Bichon Frise. In double coated breeds, hair growth and the thickness of the undercoat is largely responsive to the environment. Cold months call for a thick undercoat where air can be trapped right next to the outer layer of the skin. Think of it like a wetsuit. A wetsuit works by trapping a thin layer of water between your body and the suit. This layer of water is then warmed by your body and water is a great conductor of heat! On the other side of this scale, warm months call for a thinner undercoat that is well-brushed and not impacted. This allows air to circulate, drawing cool air over the skin. A regular issue in double-coated breeds is an impacted undercoat. This is where the secondary hairs become matted. Air is unable to circulate, meaning it gets trapped and warmed up from the heat of the body. The issue is further compounded if you have a damp coat from rainy walks, dips in the pond or after the regular hydrotherapy session and in this scenario, skin health can be compromised. The Canine Skin Not only does the skin provide a barrier to the elements, but its very composition also provides an immunological and microbial barrier because of its bacterial community. This is known as its microbiome. The skin microbiome is made up of a range of bacteria, fungi, and viruses. They usually function symbiotically; helpful microorganisms keep potentially harmful microorganisms in check. The issue is when there is an imbalance; we know this as dysbiosis. It has been established time and time again, when dogs and humans are suffering with red and itchy skin, there have been alterations in the skin microbiome. Generally, some bacteria have grown in numbers and others have reduced. A healthy skin microbiome is necessary for the correct function of mast cells founds in the dermis and mast cells mediate inflammatory responses like hypersensitivity and allergic reactions. Subsequently, those dogs suffering with atopic dermatitis are then more sensitive to environmental allergens. It is rather easy to see how skin issues can become so complex. Unfortunately, there are a range of things that can affect the composition of the skin microbiome: – Genes – Lifestyle, including nutrition – Environment – Family make up (other pets) – Personal and home hygiene In healthy dogs the most common bacteria are proteobacteria, closely followed by firmicutes, actinobacteria, Bacteroidetes and cyanobacteria. Interestingly, healthy dogs have a higher community of beta proteobacteria ralstonia spp. than those dogs suffering with allergies. The type of bacteria also varies depending on the site of the body, for example, there will be different bacteria found between toe digits to that found in the groin area. Findings Here This is because all bacteria have their own needs to survive. They need food, water and the correct environment which includes a specific temperature, to them. Some bacteria will thrive in cooler temperatures, some prefer warmer climates. This is why we need to pay attention to the coat condition of your double coated breed. Your dog will have their own community of bacteria on their skin. Some bacteria will outnumber others. Which bacteria thrive will largely depend on your dog’s lifestyle, including nutrition. If your double coated breed has gotten wet on a rainy walk or loves swimming, they will get a damp coat. You may towel them off and allow them to dry off in front of the fire or radiator. Star fishing in a centrally heated home is quite far removed from the
There can be a number of reasons why your dog may be suffering with their ears. We’ve compiled some of the more common ones. The Link Between Sensitivities and Itchy Ears Itchy ears often go hand in hand with sensitivities – so you may notice digestive issues alongside itchy ears, paws and more. In order to optimise gut health, check out our blog here: 7 Steps to Optimal Gut Health For Pets We can often look to bacterial overgrowth in fuelling those itchy ears, and yeast is often the culprit. Gut Guardian What is Yeast? Candida is an opportunistic fungal pathogen. It is a normal part of the gastrointestinal flora and genital tracts. Healthy systems are more than capable of keeping it in check with their beneficial bacteria, but issues arise when there aren’t enough good guys to keep the bad guys in check, this is what we know as dysbiosis and it can occur in the microbiome of the gut, but also the skin and more! Is Your Dog A Yeasty Beast? Factors that can contribute to dysbiosis: Chronic or excessive antibiotic use Stress Environmental toxins; bisphenol, phthalates, heavy metals, pesticides Poor gut integrity Nutrition Weakened immune function But there are a few other factors to consider when we are addressing our dog’s itchy ears… Why Is My Dog’s Ear Itchy? Anatomy or Breed Certain breeds with those long ears; the ones who end up dragging them in their food or water bowl can be more likely to suffer with bacterial overgrowth. We’re thinking spaniel or setters here. Those long ears provide a warm and moist environment for certain bacteria to thrive. It’s also a consideration for those breeds with greater amounts of hair inside their ear, those who your groomer recommends plucking out! We’re thinking poodles and alike. Whilst it may be a haven for certain bacteria having the hair there, if there is trauma through the act of plucking, we could inadvertently be opening the skin up to infection. In this scenario, it can often feel like you’re stuck between a rock and a hard place. Type of Food Fed Yeasts seem to like sugar as fuel, so diets high in grains, starches and other carbohydrates seem to contribute to an overgrowth. Generally, certain beneficial bacteria will metabolise these sugars, keeping candida in check by disrupting its food supply, but in the absence of good bacteria, candida is partying it down at the all-you-can-eat buffet! Whilst we advocate a fresh food diet, in cases of bacterial overgrowth it can be sensible to avoid certain fruits whilst getting a handle on the situation – fruit contains sugar too! Water Babies! Those dogs who love to swim or spend time at hydro can be more prone to ear issues. Again, it creates a perfect environment for certain bacteria to thrive when they are warm and damp. It’s always best to dry your dog’s ears after spending time in water. Especially with those warmer temperatures in hydro pools. Location of walks Where your dog walks or runs can mean exposure to certain grass seeds which can find their way into our dog’s ears. Not only are they initially painful and irritating, if not removed they can cause a whole host of further issues. Parasites Our dogs can be exposed to fleas, ticks or mites which can cause itching. If you would like to learn more about parasites and natural approaches to managing them, check out our blogs below: Parasites and What You Really Need To Know Natural Flea and Worming Treatments Ear Issues as a Report Card Ear issues, or rather itchy ears, can often seem like a never-ending battle, and this is largely because they’re seen as a symptomology to treat. Perhaps we need to see them as a report card. Of course, they could be telling us that our dog has been swimming and we forgot to dry their ears, or they could be telling us there’s a lodged grass seed which needs attention. There could also be a parasite burden. But they could also tell us that our dog’s immune system is a little out of whack; perhaps our dog never managed to rebalance that Th response. They could be telling us our companion’s microbial community isn’t harmonious. Our dog’s ears could be the sign our dog’s food isn’t suiting them and we need to find alternatives. Those ears could also be showing us that there is an excessive burden on detoxification pathways in the body. The reason ear issues often become chronic is because the root cause is rarely explored. We’d be looking to address immune balance and function: Do We Need To Boost Our Pet’s Immune System? We’d be supporting digestive health: Optimal Gut Health For Pets We’d be considering toxin burden: Does my Pet Need To Detox? Liver Guard And we may be considering an elimination diet: Elimination Diets For Dogs But these are only some pieces of the puzzle, we have decades of experience exploring the root cause of symptoms, so head on over to our services page to see how we can help your dog. Thanks for reading, MPN Team
The term allergy is commonly used within the pet nutrition realm. Whilst allergies to cleaning products or compounds in the environment do occur, the true incidence of food allergy in dogs is quite low. Whilst allergies do exist, we tend to see a higher number of intolerances, so what’s the difference and do we need to approach them differently? Let’s take a look at allergies and intolerances in dogs. What is a food allergy? A food allergy or other allergic response is caused by an IgE antibody reacting towards that allergen. IgE binds to mast cells to promote histamine release. In short, the immune system has sensed the particle and wants to get rid of it at all costs. You’ll know the hallmark signs of an allergy if you are unfortunate to suffer with hay fever, but the common symptoms of an allergy include: Itching Hives Swelling Coughing Sneezing/wheezing Watery eyes Anaphylaxis What is a food intolerance? In the case of a food intolerance, we tend to discuss it in terms of IgG. IgG is the work horse antibody; it is the soldier, the memory antibody. This is what gets drafted when your dog is exposed to something they have already figured out a response to. Symptoms usually begin within a few hours of eating the food that your dog is intolerant to but it’s important to note that symptoms can be delayed by up to 48 hours and last for hours or even days, making the offending food especially difficult to pinpoint. IgG’s are mostly raised from the barrier mucosa in the digestive system. After a meal, there are both antibodies and complexes of food antigens bound to specific IgG’s. These complexes are quickly cleared by the reticuloendothelial system. Clinical observations suggest that due to gut inflammation and permeability (leaky gut), the digestive system is unable to digest the proteins effectively which subsequently raises IgG response to certain foods. Chronic intestinal inflammations and permeability are related to and possibly responsible for food IgG sensitivity. A point to note is that 90% of food reactivity comes from IgG’s. Intolerances can be changeable, but allergies tend to be for life and only account for around 10% of food reactivity. The common signs of an intolerance include, and are not limited to: Poor growth in young pets Itching Vomiting Diarrhoea Flatulence Recurring ear issues Acid reflux SIBO Pain or discomfort Loss of appetite As you have gathered there is a glitch in immune function in both allergies and intolerances, but we must also consider the function of the digestive system when we are tackling intolerances. It’s important to note that IgG’s come in different categories but to keep it simple, they are generally defined as cyclic or fixed. A common IgG reaction is cyclic and can take around 3 months to disappear/change. A fixed Intolerance tends to linger for longer and can take around 6 months to disappear/change, what this means is there is no quick fix to support your dog who suffers with intolerances, we’re in it for the long haul. How to Support the Intolerant Dog First of all, we prime and reset the digestive system, and this includes starting with an elimination diet, but also includes gut healing and immune balancing protocols. We follow the 4 R’s. – Remove – carry out an elimination diet. Raw or lightly cooked is the best way to do this. Cooked foods can take pressure off the digestive system, which in these cases is beneficial. Start with novel proteins (proteins your dog’s immune system has not seen before) for example, horse, ostrich, kangaroo and hare are generally well tolerated. Horse is lean too, so a great option if digestive function isn’t where it needs to be, yet. Feed this novel protein for 4-12 weeks. Ideally if you land on a novel protein that helps the itch/digestive discomfort or doesn’t make it any worse, we recommend remaining on this protein for 12 weeks. As we noted this is the time it takes for an intolerance to change. We then introduce other novel proteins – but at no more than one per week and sticking to single source. Treats need to match too! If there are signs of intolerance, then remove that protein and go back to a protein you believe is best tolerated. Notice that it’s called an elimination diet, and not an elimination lifestyle. The overall aim is to eventually maintain a strong diversity in the diet as we know this supports optimal gut health. We would be looking to reintroduce more common proteins as time went on – but this takes time. We also practice the same process when reintroducing any fruit or vegetables – one at a time, over time. It can also be worthwhile opting for a low-histamine approach when reintroducing too. – Repair – support immunity and gut healing. Include ingredients like slippery elm, de-glycerised liquorice, glutamine, and N-acetyl-glucosamine. It is also important to consider how existing medications are affecting gut healing for example, steroid use impairs intestinal absorption which is linked to several gastrointestinal dysfunctions. But, because of their anti-inflammatory and immunosuppressive activities, they are often prescribed in cases of allergies or intolerance. Findings here – Restore – optimise microbiome health As the microbiome is key in the development of the immune system, supporting this is essential. However, the introduction of specific pre and probiotic foods or supplements is sometimes best left for a few weeks into your plan, especially when carrying out an elimination diet. There may be probiotics on the market that contain protein sources not indicated on the label – always check with the manufacturer what is contained in their product and indicate that you are carrying out an elimination diet, so you need accurate information. – Replenish Indigestibility of food proteins can also contribute to their antigenic nature, so consider any long-term medication use including proton pump inhibitors which affect gastric acid secretion. Ensuring HCL, pepsin and digestive enzymes are in good
For some dogs, their sensitivities can be year-round. In this instance we are considering their exposure to environmental toxins, the food they eat and how their immune system matured and subsequently functions. For other dogs there is a direct correlation with the time of year. Whilst the sun is shining and anything feels possible for us humans, it can be a miserable time for our seasonally itchy dogs. Many dogs have a sensitivity to grass sap and keeping them off the freshly mown lawn for a couple of days can help keep pesky irritation at bay, but some allergies are a little more complicated. As always, we are available to help you manage any chronic irritation suffered by your dog, but we thought we would give you some of our top tips that can come in handy when managing your seasonally itchy dog. If you would like to understand more of the mechanism of an allergy or sensitivity, then check out the wealth of information in our other blogs: Why Do Allergies in Dogs Develop? Does My Dog Need an Allergy Test? Your Pet’s Immune System Why Allergies and Itching Have Become Such an Epidemic Now, on to our top tips: 1) Support the Gut! As you will know if you read our articles on the immune system and the lymphatic system, in the gut you will find GALT, or gut-associated lymphoid tissue. The digestive tract is heavily laden with lymphocytes, macrophages and other cells that participate in immune responses. An allergy, in essence is an immune response gone bad, so we need to support immune function and that includes the part of the immune system found in the gut. In addition, in a poor functioning digestive system, rogue particles can end up leaking through the barriers. This can be in cases of periodontal disease (bacteria getting into the blood stream from plaque formation) and damage in the tight junctions in the intestinal tract. When this happens, the immune response is called to the area of the rogue particle to get rid of it. These systemic responses can lead to hypersensitivity, leaving the immune system a little too eager to do its job on a body wide level. It is therefore essential to support the barriers in the mouth; ensuring good dental hygiene but also to support the barrier of the gut. Look to lovely gut healing ingredients such as Slippery Elm, De-Glycerised Licorice, Glutamine and N-Acetyl Glucosamine. 7 Steps to Optimal Gut Health for Pets Gut Guardian 2) Consider the overuse of pharmaceutical flea and worm treatments! Whilst there is sometimes a place for the use of pharmaceutical products in high burdens of parasites, we would always advocate the use of wormcount kits to establish any burden of worms before treatment and also the use of flea repellent products over any spot-on or tablet flea treatment. The overuse of certain pharmaceutical products can place an unusual burden on many pathways in the dog’s body, compromising optimal function. It also pays to consider how often you vaccinate your pet. Vaccinosis: Damage Vaccinations Can Cause Your Pet Does My Pet Need to Detox? Natural Flea and Worming Treatments Supporting the liver and lymphatic system is essential during these times, Liver Guard can be great in this instance. Liver Guard 3) Limit Stress! Mast cells have a key role in allergic response; when they detect a substance that isn’t liked by the body, they release histamine and other chemicals into the bloodstream. Histamine makes the blood vessels expand and the surrounding skin itchy and swollen. This is known as degranulation and what’s super interesting is that stress can result in degranulation too! This may explain the red face you feel as you are getting stressed, or if you break out in hives when you’re facing a particularly stressful time in work. If you are working to tackle allergies in your dog, then it is important to remove as many stress triggers as possible, for your dog, but also you. There is this idea of co-regulation of species, that dogs can pick up when we are stressed and we’ll admit, there is nothing more stressful than seeing our dogs suffer and feeling that we aren’t getting anywhere with fixing it! It can pay to establish our own levels of stress when we are managing a poorly pooch. Check out our perceived stress scale in the following blog to help you understand your own stress levels. 5 Tips For Dealing with a Fussy Eater Calm Complex br] 4) Rinse your dog, but not wash! If you suspect your dog may have sensitivities to certain grasses or pollen, rinse their paws, undercarriage, and chest after walks. You can also wipe their muzzle, ears, and face with a damp microfibre cloth when you get home too. But avoid over-shampooing your dog. Whilst you may opt for non-toxic products, washing can skew the microbiome found on the skin of your dog and this provides a first line of defence for the immune response. The skin has its own community of microbes that can engulf and destroy pesky ones before they have chance to cause problems; frequent bathing can alter this community. So, rinse your dog to remove potential irritants, but keep the shampoo for special occasions, like fox poo events. Your Puppy’s Microbiome 5) Essential Fatty Acids Are Just That! Allergies and sensitivities are an immune response and inflammation is the hallmark of an immune response. Inflammation is a necessary process in the body, but we need just enough to solve the problem at hand. We have compounds necessary to kick start the inflammatory response, and we have compounds that reign it back in again. What we often find is that there are more compounds around to perpetuate inflammation, and not enough to reign it back in! Therefore, it can help to fill up on foods to regulate the inflammatory response. Omega-3 is a fatty acid that has regularly been linked inflammation regulation.
Possibly one of the most common ailments that we find in the dog world – some dogs just seem to react to everything! But, if we know how allergies and sensitivities develop, is it something we can tackle? Let’s take a look and consider some top tips to support your dog’s health. What is a dog allergy? An allergy is an unnecessary immune response to an innocuous substance. True allergies are often fatal. More often than not we are faced with sensitivities – which are still an immune response. What is the immune system? The purpose of the immune system is to defend itself and keep microorganisms like bacteria, viruses, and fungi out of the body and then destroy any if they happen to get in. It has three lines of defence. The innate immune system provides the first line of defence; broadly divided into physical/chemical barriers. The physical barriers include the skin and the lining of the digestive and respiratory tract. You can think of the body like a sausage; the skin, keeps everything in, but also things out. Chemical barriers include tears and saliva along with gastric acid. But also, the microbiome – which is the community of microbes found in the mouth, lungs, gut and on the skin. We then have the innate immune system – which is for want of a better phrase a row of white blood cells (and other participants) that engulf and destroy invaders. The third defence is acquired or adaptive immunity – this is the memory bank. The cells involved in this response help the body remember antigens that it has encountered before – so it can mount a quicker response before the harmful pathogen causes any damage. The immune system is trained to recognise its own cells as self and leave them to do their jobs. It is trained to recognise anything that isn’t self and attack it. When it works, it works brilliantly and, well, us and our dogs survive. But, it can get a little too enthusiastic and start responding to things it doesn’t really need to. This is what we see as autoimmunity, but also allergies and sensitivities and there are a number of reasons for this. Allergies and Sensitivities First of all, we may be dealing with an immature immune system, and this all starts back in puppyhood. When we talk about immune responses, we tend to reference Th1 and Th2. They are both necessary responses, but a Th2 response is more commonly associated with allergy. During pregnancy, a strong Th2 response is present to reduce the risk of miscarriage. What this means is that puppies are born with a Th2 dominance. This then needs to be balanced and the way in which this occurs is through microbial exposure. This is what we know as immune tolerance – the immune systems develop through exposure to controlled challenge. The immune system is like a computer; it has software, but it needs data. The microbial ecosystem in various mucosal sites is important for the development of the immune system. The young gastrointestinal tract is colonised soon after birth by a variety of commensal bacteria that influence the development of the immune response both in the gut and systemically. The mucosal immune system in the gut must avoid adverse immune responses to dietary antigens and commensals in the new microbial ecosystem while remaining able to mount an effective response to pathogenic organisms. In an ideal world, our pets will develop a heathy immune system, and they will have sufficient immune tolerance but also eliminate threats when necessary. But we don’t always live in an ideal world. Gut Guardian br] So what else can cause issues with immune responses? Often allergies and sensitivities are associated with poor barrier function; so there may be damaged or broken skin, a poor microbiome, or damage to the integrity of the gut. Think of it like an army. If you have a row of soldiers who are standing shoulder to shoulder, you stand a good chance against the enemy. Once soldiers start falling, opportunities arise for the enemy to get through. When skin is damaged, antigens spot their opportunity and sneak in through the gaps. The same occurs in the gut. Cells sit tightly together, but when cell integrity fails, under digested food particles and pathogens see their opportunity and sneak out into circulation. The immune system spots these particles – realises they shouldn’t be there, so mounts a response. Inflammation is a key part of this response. The issue is when the barrier remains compromised, more particles sneak through and so you end up in a chronic state of inflammation. Barrier dysfunction can occur for a number of reasons: Genetic glitches Microbiome dysbiosis Long-term use of medication Toxins Environmental exposure Detoxification Pathways The more inflammatory compounds you have in the presence of a response, the more anti-inflammatory compounds you will need to counter this response. There will also be a heightened need for compounds that break down inflammatory molecules like histamine. Those suffering with allergic disease often have a higher baseline of histamine, and so clearance of this is important too. What this means is that detoxification pathways need to be running as smoothly as possible. Liver Guard Detoxification of dietary histamine normally occurs in intestinal epithelial cells via the enzyme diamine oxidase (DAO) as well as histamine-N-methyltransferase (HNMT) in the liver. What’s interesting is that there are polymorphisms in the genes that code for the DAO enzyme, but certain medications, including over the counter products are seen to inhibit the activity of DAO enzyme too. They include: Analgesics – morphine, NSAIDs Antiarrhythmics Antibiotics Antifungals Antimalarial Diuretics Motility agents Muscle relaxants Vitamins – ascorbic acid, thiamine In addition, detoxification pathways in general are nutrient demanding and they also produce a high number of free radicals. Sufficient levels of key vitamins and minerals like vitamin A, C, E, B1, B2, B3 and iron, along with cysteine are essential. Does My Pet Need To
We sometimes talk about intolerances and allergies like this is the only thing that can cause your cat or dog’s itching. There can be so many reasons, layered reasons and some more serious than others. Here we explore some of the undetected and misdiagnosed reasons for your dog being itchy. Adrenal function The adrenal glands are located just in front of the kidneys. You will recognise them from when we discuss the stress response more often than not. The adrenal gland has 2 parts—the cortex and the medulla. The adrenal cortex is subdivided into 3 layers, and each layer produces a different set of steroid hormones. The outer layer produces the mineralocorticoids, which help regulate sodium and potassium salts. The middle layer produces glucocorticoids, which are involved in metabolising nutrients and reducing inflammation and immune responses. Finally, the inner layer produces sex hormones such as oestrogen, progesterone, and androgens. The adrenal medulla plays an important role in response to stress or low blood sugar levels in the body. It releases adrenaline and noradrenaline, both of which increase heart rate and blood pressure, increase blood sugar and slow digestion; the hallmark responses when us or our dogs are exposed to a stress trigger. The adrenal glands are part of the endocrine system – which is simply a system of glands that release chemical messengers called hormones. The endocrine system influences almost every cell, organ, and function in the body. So, if there is any issue in any part of it, things can start to go wrong. The two most common ways in which adrenal glands cause health issues are by producing too little or too much of certain hormones, which leads to hormonal imbalances. Hyperadrenocorticism (Cushing’s Disease) due to an excess of cortisol production frequently causes dogs to itch, lose hair, have thin skin with dark pigment, drink excessively and have recurring skin problems. But this raises another point, even if there are no physiological issues with the adrenal glands, high cortisol levels due to daily stress can also lead to itchy skin! Thyroid Function We’ll continue with the hormones for a minute and look at thyroid function. The thyroid is a butterfly shaped gland found in the neck. One of its main functions is to produce hormones to regulate the body’s metabolism, the process that turns food into energy. This too can produce too many hormones, or too few. These conditions are known as hyperthyroidism and hypothyroidism respectively. Hypothyroidism Hyperthyroidism Hyperthyroidism in Cats Skin issues are regularly noted in times of thyroid dysfunction, and this includes itchiness. Kidney Function Intense itchiness often accompanies late-stage kidney disease, and whilst the jury is out on the exact reasons behind it, it is thought that it’s relating to the build up of toxins in the body. This leads us nicely into the same itchy symptoms associated with early-stage liver disease, and this is considered for similar reasons. Detoxification Detoxification is carried out by a range of mechanisms, and this comes in particularly handy if one pathway is overwhelmed, another can pick up the slack. The Liver The liver neutralises a range of toxic chemicals, both those produced internally (waste from used hormones or neurotransmitters for example) and those from the environment, like air pollution, pesticides, and food additives. It does this by filtering the blood to remove large toxins, synthesising, and secreting bile and lastly enzymatically disassembling unwanted chemicals found in the body. Liver Guard Enzymatic Detoxification This enzymatical detoxification occurs in three phases. Phase I directly neutralises chemicals and changes them into new metabolites. These are then processed by phase II enzymes. This is known as the conjugation phase, which in short, liver enzymes attach small chemicals to the toxin. There are many ways in which this is done, it all depends on the type of chemical the liver is trying to manage. Phase I results in high levels of reactive oxygen species so antioxidant levels are key in modulating potential damage. Phase II is nutrient demanding and sufficient levels of key vitamins and minerals like vitamin A, C, E, B1, B2, B3 and iron are essential. Phase III is the elimination phase. For optimal excretion of toxins through the digestive system, gut health is vitally important. Maintaining the mucosal barrier is key for gut health along with supporting motility. The kidneys will also filter and process toxins from circulation, excreting them as urine. The skin also forms as an elimination pathway. This is why detoxification issues can result in skin issues. In cases of liver disease, it is considered that bile salt deposits under the skin, which results in itchiness. The most important thing to do to support detoxification is to avoid exposure in the first place, so consider how much you and your dog are exposed to: Pesticides Heavy smoke Phthalates Mould Medications like steroids, antibiotics, and painkillers Heavy metals Cleaning products Air fresheners Eating foods cooked at high temperatures (most commercial dry foods) This list is not exhaustive, but it is a place to start. This mechanism also applies to vaccines. There is increasing evidence that over-vaccination is associated with the development or aggravation of immune-mediated disorders and chronic diseases in individual pets that are genetically predisposed. The primary role of the immune system in dogs is to protect against foreign invaders, or abnormal cells that invade or attack. The immune system must distinguish between self and non-self. Substances that stimulate a response are antigens. These can be contained within bacteria, viruses or microorganisms or cancer cells. They may also exist on their own, like pollen or food particles. There are three lines of defence, physical barriers, nonspecific immunity, and specific immunity. But the immune system does not always function properly, it can be underactive and overactive. An underactive system puts the animal at risk of infection, but an overactive immune system can attack parts of its body that it misidentifies as being foreign. This is what happens in autoimmune conditions. The immune system can also overreact
