Here at My Pet Nutritionist, we know how important your pet’s diet is, and how their diet can have a huge effect on their health and longevity. As part of their balanced diet, there are many vital macronutrients and micronutrients required in the correct quantities to ensure optimum health. One of the essential micronutrients required in the diet of both dogs and cats, is Choline; but why is it so important? Read on to find out! What is choline? Choline is an essential micronutrient; however it is neither a mineral nor a vitamin! It is a water soluble organic compound. Essential nutrients are nutrients the target species MUST consume within their diet. These nutrients are needed by the body, but the body cannot produce enough; meaning the diet needs to include them. As nutritional science has evolved over the years, move and more essential nutrients have been discovered. Choline is one of the newest discoveries in the nutrition world, being recognised as an essential micronutrient only since 1998 by the Institute of Medicine! When reading literature, you may find Choline is grouped with B Vitamins due to its similar functions within the body. Another important nutrient is Betaine, which is a metabolite of Choline. When Choline is metabolised, Betaine is formed, which has many health benefits such as protecting cells from osmotic stress (keeping cells perfectly hydrated, and stopping them from shrinking or swelling), and acting as a methyl donor, which plays a vital role in liver health, and is heavily involved in other major internal systems. Findings Here Findings Here Why is Choline Important? Choline, as an essential nutrient, is extremely important. It plays a huge role in many systems within the body from cells to metabolism, to DNA, to the nervous system. Let’s take a closer look at the roles it plays in the body: Cell Membranes: Choline is largely responsible for supporting the integrity of cell membranes, due to its ability to create the necessary fats to keep cell structure strong. Cell messengers: there are a number of compounds that act as cell messengers – passing signals between cells to allow them to ‘communicate’. Choline helps to produce these compounds. DNA Synthesis: like Vitamins B9 (Folate) and B12 (Cobalamin), Choline is involved in the synthesis of DNA. DNA is the body’s genetic code, so it is incredibly important to keep it healthy. Metabolism and transport of fat and cholesterol: this mainly improves the health of the liver. Choline helps to remove cholesterol from an individual’s liver by producing the responsible substance. If your pet is deficient in Choline, fat and cholesterol can build up in the liver, which would dampen it’s functionality. Benefits the nervous system: when Choline combines with an acetyl group, a reaction occurs using an enzyme called choline acetyltransferase as the catalyst. The result of this reaction is the production of Acetylcholine – an important neurotransmitter. Acetylcholine plays a major role in many aspects of health including muscle movement, memory/cognitive alertness and heartbeat regulation. Essential for healthy pancreas: studies show that a deficiency in Choline can be linked to pancreatitis. These studies suggest that supplementation with Choline can protect pancreatic cells, and reduce the risk of pancreatitis flares. One of the main pancreatic issues in those lacking a sufficient amount of Choline, is disruption to the exocrine system. Methylation: probably one of the most important roles of Choline in the body is Methylation. Methylation is incredibly important as it is the process which creates the Myelin sheath; the protective layer coating nerves in the body. These nerves affect brain health, and general nervous system health throughout the body. Benefits during pregnancy: during pregnancy and foetal development, choline is extremely important as it aids cognitive development in the maturing foetus – this sets young puppies and kittens up for better cognitive function when born and ageing. Findings Here Findings Here Findings Here Findings Here How Much Choline Does My Pet Need? Cats and dogs require different amounts of choline – in fact every species has different requirements for almost every nutrient, so it’s important that we tailor our pet’s nutrition to suit their species. With that in mind, how much choline is required for cats, and how much for dogs? Studies suggest that adult cats require a minimum of 800mg of Choline per kilogram of FRESH food per day, and that there is no upper tolerable limit in cats. in terms of dry food matter, this is around 3500mg/kg. Kittens may require a little more than this recommendation. Dogs require a different amount of Choline in their diet to cats. Adult dogs require at least 474mg per kilogram of FRESH food in their diet per day. in terms of dry matter, this value is around 2500mg/kg. Our nutritionists recommend around 800mg per kg of fresh food! Puppies may require a little extra. Sources of Choline When it comes to looking at pet foods on the market, most will contain Choline – however the form the choline is given in, may affect it’s efficacy. Ultra processed foods, such as dry extruded foods, may not be the best source of Choline for your pet; during the manufacture of these foods, the whole food ingredients are subject to high temperatures and multiple processing techniques which can damage nutrient quality and bioavailability. These foods are often sprayed with synthetic vitamins at he end of manufacture in order to reach minimum guidelines. At My Pet Nutritionist, we advocate for a fresh diet, where nutrients are sought mainly through the fresh ingredients included in the recipe. Some fresh food ingredients, rich in Choline, include: Liver – 209mg per 50g Eggs (especially egg yolk!) – 147mg per egg Kidney – 105mg per 50g Cod – 74mg per 50g Beef – 70mg per 50g Pork – 43mg per 50g Poultry – 36mg per 50g Brussels Sprouts – 31mg per 50g Shiitake Mushrooms – 29.7mg per 50g Cauliflower – 22mg per 50g Broccoli – 16mg per 50g Salmon – 11mg per 50g Nuts
Here at My Pet Nutritionist, we use a combination of healthy diets tailored to your pet’s needs, alongside beneficial gut-friendly herbs, and nutraceuticals. These supplementary additions often come with hosts of benefits, when used in the correct way, for a specific purpose. We often get asked about the various herbs and nutraceuticals we recommend in various blog posts and in our recipes and supplements – you can learn more about some of these here! What Are Gut Healing Herbs? Herbs high in mucilage are often known as the ‘gut healing herbs’. These herbs are usually considered to be a source of prebiotics – food for probiotics; however these herbs have another very important function when it comes to gut health! Mucilage is a soluble dietary fibre, which produces a mucus-like substance which lines the gut wall. When the gut wall is lined with this slimy textured substance, it forms a protective barrier to reduce the risk of further gut damage, and allow the gut to heal. Inflammation is then reduced due to lack of irritation. Mucilage has a fantastic soothing effect on the digestive tract too – those with acid reflux, or having recovered from illnesses like kennel cough which may cause throat irritation may find a powdered form best, due to the soothing effect of the mucilage in these herbs. As an additional benefit of these popular gut healing herbs, the mucilage can increase digestive performance resulting in better stools; this is due to the mucilage adding bulk to the stool (reducing constipation), aiding water absorption, and increasing gut motility. Some studies also suggest that mucilage rich herbs may reduce the build up of cholesterol, and aid the regulation of blood sugar levels. Frequently used mucilage herbs include slippery elm, marshmallow root, and deglycyrrhizinated liquorice root – we will look closer at these later. Findings Here Findings Here What Are Nutraceuticals? Nutraceuticals are components of foods that bring benefit to health. You may often come across plant based supplements for pets; these are packed full of nutraceuticals! Functional foods are also classed as nutraceuticals. Many nutraceuticals enhance basic nutrition, whereas some provide medicinal properties. Some benefits of using carefully selected nutraceuticals include improved overall health, prevention of chronic disease, increased longevity and all round structural support for the body. The term ‘nutraceutical’ is a combination of the words ‘nutrition’ and ‘pharmaceutical’ – meaning they share the same properties as pharmaceuticals, but are acquired through nutrition Functional herbs, antioxidants, probiotics, vitamins and minerals are all examples of the categories most commonly encountered in the world of pet nutrition. We will delve into these categories in terms of nutraceuticals later. Findings Here Findings Here When Should We Use Gut Healing Herbs and Nutraceuticals? A question we often hear at My Pet Nutritionist, is “should we be giving any supplements?” – and our answer is always “if your pet could benefit from a carefully selected supplement, then absolutely!”. It is important not to needlessly add lots of different nutraceuticals and gut healing herbs to your dog’s diet, unless they require/could benefit from it. When it comes to giving mucilage herbs, these can be incredibly beneficial in situations where gut damage is apparent. Situations a mucilage herb may be beneficial include: Allergies: due to an immune malfunction Intolerances: due to gut damage or leaky gut syndrome Following vaccines, worm or flesa treatment: these products are very damaging on the gut, so gut healing may be necessary. Acid reflux: soothes the digestive tract and reduces the risk of acid reflux Upset stomach or constipation: these herbs help to rectify loose or solid stools when needed. Great to have in the first aid cupboard! When looking at nutraceuticals, we need to look at the symptoms your dog or cat is displaying, alongside gaining a diagnosis from your veterinarian. Some types of illnesses you may use nutraceuticals for include: Joint issues Skin issues Digestive issues Cognitive health issues (anxiety etc) Vision issues As brilliant as nutraceuticals can be as part of your pet’s health regime, many do come with some contraindications with pharmaceuticals your pet may need. Contraindications are negative interactions with drugs – these interactions can often cause downregulation of the drugs themselves, leaving your pet vulnerable to disease progression. An example of this is curcumin – the active compound in turmeric. It is fantastic for joint support/arthritis, cardiovascular function, reducing inflammation, eradicating free radicals, immune support, cognitive ability and cancer prevention. The reduction in pain in those who take curcumin is vast; however some individuals may require pain pharmaceutical pain relief for their condition. Curcumin is known to downregulate the effects of some pharmaceutical analgesics, as well as various other drugs. It is always best to check with your veterinarian before starting a new nutraceutical, if your pet is on pharmaceutical drugs. Findings Here Findings Here Popular Gut Healing Herbs The three most popular gut healing herbs can all be found inside our Gut Guardian supplement, along with probiotics and chamomile. Lets take a closer look at these mucilage herbs! Marshmallow Root: this is a sweet smelling and tasting herb derived from the Althaea officinalis plant. When combined with water, it immediately forms a thick, slimy substance due to it’s high mucilage content. Traditionally, marshmallow root is used in cases of digestive or respiratory issues, and also topically to soothe skin issues. As well as being high in mucilage, it also contains high amounts of antioxidants, anti-inflammatory properties, and antibacterial properties. slippery elm: like marshmallow root, slippery elm produces a slimy substance when combined with water. It originates from the inner bark of the slippery elm tree (Ulmus rubra), and is often used to treat digestive issues, and sore throats by lining the oesophagus. DGL (deglycyrrhizinated liquorice): this herb increases mucous production in the body, which helps line the stomach, reducing the risk of harm caused by acid. DGL is thought to have properties to treat ulcers too! Findings Here Findings Here Findings Here Popular Nutraceuticals There are many nutraceuticals used in the
In part two of our focus on the diet of a senior dog, we will look further into some specific nutritional categories bringing fantastic health benefits to your senior dog. We will also go through our recommendations on what to feed your senior pet, including specific nutrients and supplements you may wish to consider! Read Part 1 here! Specific Beneficial Nutrients There are a number of macro- and micronutrient categories senior dogs would benefit greatly from to slow the ageing process down, and reduce age-related inflammation. The two main categories to analyse here are Antioxidants, and Omega Fatty Acids. Antioxidants: these are one of the most important categories of nutrients to feed your senior dog (and are highly beneficial at any age!) due to their action against oxidative stress. As dogs age, oxidative stress becomes more proliferative; it’s a natural part of ageing! Oxidative stress is caused by ‘free radicals’ – unstable oxygen molecules missing an electron. Free radicals damage all parts of the body from organs to joints, causing joint degeneration, cancer, altering DNA, neurodegenerative diseases, adverse alteration of fats and proteins, and other diseases like diabetes, so it is incredibly important to combat these cells as best you can. Antioxidants tackle and remove free radicals from the body, leading to less oxidative stress, and therefore slower ageing. Some excellent sources to think about including in your senior dog’s diet include blueberries, strawberries, artichoke, goji berries, red cabbage, kale, ginger, spinach, parsley, pecans (in small amounts due to fat content), fresh garlic (avoid in Japanese breeds) and rosemary (avoid in epileptic dogs). Omegas Fatty Acids: this group of fats are another incredibly important category of nutrients to include in your senior dog’s diet, specifically Omega 3. The two ‘main’ omega fatty acids are Omega 3 and 6 – both are essential. Omega 9 is present in the diet too, but doesn’t add as many benefits to the dog’s health as Omegas 3 and 6. Omega 6 fatty acids called Linolenic Acid (LA) and Arachidonic Acid (ARA) are inherently inflammatory. The only non-inflammatory Omega 6 is Gamma-linolenic Acid (GLA). Omega 6 brings many benefits to the health of the dog despite it’s inflammatory properties, including control of hormones, however as it is naturally in abundance in our carnivorous pets’ meat based diet, we need to balance the inflammation out! This is where Omega 3 comes in! Omega 3 includes Eicosapentaenoic Acid (EPA), Alpha-linolenic Acid (ALA) and Docosahexaenoic Acid (DHA), and is inherently anti-inflammatory. The anti-inflammatory properties of Omega 3 Fatty Acids balance out the inflammation caused by Omega 6 Fatty Acids. EPA is the main inflammation reducer, while ALA aids immune and heart health, and DHA aids cognitive health and development. Some excellent sources of Omega 3 to include in your dog’s diet include fatty fish and fish oils, algal oil, flax and chia seed, oysters and eggs. You can read more about choosing an omega supplement for your pet here! Findings Here Findings Here Findings Here What Type of Food Should I Feed? The dog food market really is a minefield! There are many options of different food types, each claiming to be the best! Our ethos here at My Pet Nutritionist is to feed as fresh food as possible! Minimal processing is a major factor in healthy ageing and longevity. In this article, we are going to take a closer look at dry food, fresh cooked food, and raw food. Dry food is not a diet we would generally recommend, especially not for a senior dog! But why? High carb: carbohydrates can have an inflammatory effect on our pets. Dry foods are typically between 30 and 60% carbohydrate – sometimes even higher! Manufacturing process: these foods undergo a huge amount of processing. During the cycle of production from raw ingredient to bag, these foods are subject to up to 4 separate high-heat processes, each time reducing nutritional quality. Synthetic vitamins and minerals: our senior dogs may not be able to utilise the synthetic vitamins and minerals often sprayed onto the dry food at the end of the manufacturing process, deeming them useless. Glyphosate: due to the extreme manufacturing process, glyphosate production occurs. This is the main ingredient effective against killing weeds, but it is linked with cancer and damage of the gut microbiome. Mycotoxins and Aflatoxins: mycotoxins are chemical compounds caused by mould and can lead to vomiting and seizures. Aflatoxins are also caused by mould in food and can lead to cancer and liver damage. Storage mites: before bagging, dry foods are often stored in large hoppers – and even after bagging, the shelf life is very long, encouraging storage mites which can trigger allergies. Advanced Glycation End Products: shortened to AGEs, these harmful chemical compounds are produced during manufacturing, and a linked to cancers, inflammation, oxidative stress and premature ageing. Why do we advocate for a fresh cooked, or raw diet? Which is best for senior dogs? Fresh food is minimally processed, meaning the harmful compounds listed above do not form, reducing the risk of inflammation, oxidative stress and other disease in the body. As the ingredients are still in their whole, natural form they are nutrient dense, and provide the body with excellent nutrition! Another major benefit to fresh food, is that it is high in moisture – moisture in the diet is essential for kidney and gut health, both of which are known to worsen during the ageing process! As the gut motility of senior dogs can reduce, and other changes in the gut naturally occur, many seniors cope best with fresh cooked food as opposed to raw food – though some do still tolerate raw food! We have an extensive array of well formulated and balanced meal recipes for dogs on our website! Our Recommendations There are various aspects of diet we actively encourage owners of senior dogs to include in their dog’s feeding regime. Some may benefit from a more tailored 1-2-1 approach with one of our consultants, however our general
Here at My Pet Nutritionist, we help pet owners help their beloved dogs and cats with all aspects of health and nutrition. Those we consult for include all ages, from puppyhood right through to old age. Our golden oldies deserve just as much love and care as their younger counterparts! As a dog ages, their dietary needs may change – but how? In this bumper 2-part blog, we take a look at the dietary changes your senior dog may need to stay happy, healthy and pain free! Is My Dog a Senior? This is a question we here ever so frequently! Is your dog a senior? Is there a specific age your dog becomes a ‘senior’? what are the signs your dog is becoming a senior? Many processed dog food manufacturers will class a senior dog as ‘7 years plus’ – however we know there are so many contributing factors to a dog becoming a ‘senior’, and this isn’t always at 7 years of age! Factors affecting a dog’s ageing include: Breed: generally speaking, larger breeds will hit their senior years far earlier than smaller breeds. Breeds with predispositions to health conditions may also reach senior years earlier than those without. Genetics: a dog’s family genetics/history can affect the age they reach senior years. Medical history: if your pet has had any health complications growing up, any medical reactions, infections etc, these may cause senior years to come sooner. A dog’s neutering status, or the time they were neutered may also contribute to ageing. Dietary History: a dog fed a gut-friendly diet, full of natural nutrients, with minimal processing for life is more likely to reach senior years later than those fed an ultra-processed diet full of synthetic micronutrients. Ultra-processed dry foods also tend to have a high content of pro-ageing substances called Advanced Glycation End-Products (AGEs) which cause faster ageing. Exposure to toxins: toxin exposure can cause disruption in the endocrine (hormone) system, and cause gut stress which usually comes hand in hand with life shortening conditions, causing senior years to approach quickly. These toxins can be anything from flea and worm medications to environmental toxins both in the home and out and about. Behavioural History: even your dog’s behaviour can have an effect on longevity! This may seem like an odd link, but behavioural stress can have an effect on physical stress, and vice versa. The pathway between the brain and gut, known as the gut-brain axis is at play here! Physical stress on the body, caused by behavioural stress, will speed up the process of ageing. Signs that your dog is entering their senior years include: Weight loss Reduced hearing Reduce eyesight Increased fatigue Less willingness to exercise Reduced cognitive ability Stiffness Reduced appetite Increased water consumption Development of lumps and bumps Lack of balance and stability. Of course, as your dog enters the early staged of senior-hood, these symptoms may be mild, and your dog may only display a few. As your dog progresses through their senior years, more symptoms may appear, or existing symptoms may worsen. Nutritional Needs of a Senior Dog As your dog ages, various changes occur throughout their body which require some nutritional tweaks to ensure optimum health continues. These changes include various internal systems in the body such as: Gut health: the gut of an ageing dog can be subject to various changes affecting gut motility, nutrient absorption and processing. Digestive capabilities often occur due to gut degeneration. Brain health: ageing canines are often subject to cognitive decline. Joint health: one of the major pathways from the gut is the gut-joint axis. When the senior dog’s gut is compromised, joint conditions can become more prominent. Senior dogs generally require more joint support than younger dogs. Dental Health: dental conditions like gingivitis, tooth decay, periodontal disease, tooth fractures and tooth resorption are often seen in older dogs. Kidney Health: kidney disease is one of the more common age-related diseases we often hear about here at My Pet Nutritionist, as older dogs are more susceptible to Chronic Kidney Disease; a progressive disease. Heart Health: as the heart is a muscle, over time it can begin to fatigue. Statistically, around 75% of senior dogs suffer some sort of heart disease! Findings Here Findings Here Findings Here Findings Here When it comes to nutritional composition, we need to look closely at the macronutrients and micronutrients in your dog’s diet; both quantities of, and types/sources of. Macronutrients are the main nutrients our bodies require in larger amounts; let’s take a look these requirements for a senior dog: Protein: The building blocks of protein are called Amino Acids. Amino Acids are essential for pretty much everything in the body to form and function normally, including muscles, tendons, ligaments, cartilage, hair, nails and skin. Protein is also used in the endocrine system, to enable the healthy production of hormones throughout the body. As the dog ages, protein deficiencies become more common, which can lead to absorption issues and muscle degradation which ultimately affects mobility. A meat based, moderate-high protein diet is advisable for senior dogs. Fat: as dogs become less active due to the natural ageing process, a low fat diet may be advisable. Feeding a high fat diet when activity levels are waning may cause weight gain which puts pressure on joints and other parts of the body. The type of fat included in the diet also makes a difference! Saturated fats are the type we ideally do not want much of, however Omega 3 Fatty Acids are known for their anti-inflammatory properties, and are an important part of s senior dog’s diet! More on this later. Carbohydrate: ‘complex’ carbs which are high in fibre may be a great addition to your pet’s diet, to improve digestion, regulate metabolism and help maintain the immune and nervous systems. Higher fibre carbohydrate options include kale, broccoli and leafy green vegetables. Other ‘complex’ carbs that are ok to be fed in small amounts include sweet potato, pumpkin, banana, berries
At My Pet Nutritionist, we help a lot of dogs and cats with kidney and liver disease. These can be caused by many other health aspects, and both require management with diet, supplements, and lifestyle changes, alongside conventional veterinary medicine. Those who we have helped with kidney or liver disease will have been recommended, and formulated a gently cooked diet, specific to the pet’s condition. Why do we recommend a cooked diet for these pets? Find out with us in this blog post as we look at kidney and liver function, and why when diseased, these require a cooked diet! Role of the Kidneys In order to understand why a cooked diet is best for kidney and liver disease, it’s important to know what the kidney and liver do, what stresses them, and what kidney and liver disease are. First up, kidneys. The mammalian body has two kidneys, which are shaped much like a bean (hence the bean commonly used in Mexican cookery among other cuisines being called a ‘kidney bean’; this is the shape of your pet’s, an your own kidneys). They are found in the abdomen of your pet, either side of the spine for dogs, and just below the spine for cats. The kidneys are an incredibly important organ, and without them, the body would be extremely toxic. Kidneys are essentially the body’s built in filter! They remove waste products and substances from both the blood, and the urine. The level of many components of a health blood stream is largely controlled by the kidneys, which also contributes to control of blood pressure. The kidneys are also involved in the endocrine system, which stimulate red blood cell production, and help to regulate calcium homeostasis. You can learn more about kidney function here. As with any organ, it is important to refrain from overstressing the kidneys. There are various factors which may contribute to added pressure on the kidneys such as: High blood pressure High blood sugar (diabetic pets can be more at risk of kidney disease) High sodium levels in the diet Prolonged use of NSAID drugs High phosphorous levels in the diet Processed foods Too much protein in the diet Poor quality protein in the diet Dogs and cats with kidney disease can be at stage 1-4, each stage worsening. When the kidneys are under immense pressure, kidney disease often occurs. We do see a lot of cases of Chronic Kidney Disease (CKD), as well as other kidney diseases in practice at My Pet Nutritionist. Kidney disease can be trickier to diagnose in cats because they often urinate and drink where the owner is unable to monitor, but is seen in a staggering 1 in 3 cats! Symptoms of kidney disease include: Drinking excessively (polydipsia) Increased urination (polyuria) Vomiting and diarrhoea Rapid weight loss Reduced appetite Anaemia (pale gums and tongue) Increased blood pressure Loss of eyesight Reduced bone density You can learn more about kidney disease for cats here and for dogs here. Role of the Liver Next up, the liver. The liver is a sort of triangle shaped organ, which sits inside the ribcage in both cats and dogs. It consists of 6 lobes, and is extremely important! Much like the kidneys, blood passes through the liver to be cleaned. It plays many roles in the body, such as: Detoxification of the blood from certain medications and environmental toxins Converts ammonia to urea Produces bile, which breaks down fats Breaks down nutrients in the blood, and makes them useable Synthesises some proteins for healthy blood plasma Stores iron Converts excess glucose to glycogen, which is stored in the liver, and can be used as an energy source Regulates blood clotting Helps to remove bacteria from within the blood stream Removes bilirubin from the blood When it comes to stressing the liver, there are various consumables which can put added pressure on the liver, and ultimately cause it to become sluggish, and often results in the onset of liver disease. Feeding a high fat diet puts a huge strain on the liver, as it is unable to produce enough bile quickly enough to digest the fats. High carbohydrate (or sugary) diets can also add pressure on the liver, as well as diets too high in salt. Liver Guard We also need to look at reducing the chemical intake of your pet! Since the liver plays a role in blood detoxification of certain medications, it is wise to use natural flea and worm preventatives, since the often prescribed pharmaceutical chewable options on the market sadly release toxins into your pet’s blood stream, making extra work for the liver. A lot of reports from pet owners with pets affected by these chewable flea, tick and worm treatments have reported a reduction in liver function, or the onset of liver disease! Those with liver disease, often caused by frequent overworking of the liver, tends to be more common in dogs than in cats, but is seen in both species. The symptoms you may see in liver disease patients include: Loss of appetite Rapid weight loss Vomiting and diarrhoea Neurological activity such as seizures (hepatic encephalopathy) Jaundice (yellowing to the eyes and skin) Excessive drinking (polydipsia) Excessive urination (polyuria) Reduction in blood clotting Abdominal bloating You can learn more about liver disease for cats and dogs here. Why Cooked Food? When our customers come to us with a pet with liver or kidney disease, we recommend they switch to a cooked diet. Cooked food is very much the most appropriate option for pets with kidney or liver disease, for a few reasons: Lower phosphorous levels for kidneys: when a pet has kidney disease, feeding low phosphorous is incredibly important because when the kidneys are damaged, they struggle to remove phosphorous from the blood. While phosphorous is an important nutrient for strong bones and teeth, as well as muscular recovery, in excessive amounts, it can affect bone health, and cardiovascular health. When the ingredients in a properly balanced recipe
In the modern dog world, there are so many controversies over various food items, from salmon oil to raw eggs to coconut oil to garlic. Here at My Pet Nutritionist, we like to put owners minds at ease, and help you to evaluate whether it is suitable for your pets, using both scientific and anecdotal evidence based on our professional experience. Salmon oil, raw eggs and coconut oil have all been covered within our blog to date, so now it’s time to have garlic in the spotlight! Let’s discover some myths, and truths about this powerful, often useful ingredient! What Is Garlic? This may seem a bit of an obvious section to many, but you may learn something new too! Garlic (Latin name: Allium sativum), is the bulb of a flowering plant, and is a potent addition to foods in the human world, for flavour as well as medicine. It’s closest relatives are onions, leeks, shallots and chives. Humans have consumed garlic since the times of Ancient Egypt. Originating from south and central Asia, and Iran, the vast majority of the world’s garlic production occurs in China. The chemical make up of garlic gives it it’s many beneficial uses in both the human and dog world, however there are caveats when it comes to garlic and dogs! Allicin, ajoene and polysulfides are among the most powerful sulfur containing compounds, alongside lots of useful enzymes, flavonoids (often useful as antioxidants), and saponins (which have great cancer risk reducing properties, as well as being great for lowering blood fat and blood glucose levels. Findings Here Findings Here The Controversy Around Garlic As dog owners, we only want the best for our precious pooches! And that’s where the confusion sets in – safe? Unsafe? My vet said it’s toxic! Someone on an online dog forum said it’s toxic, but another said its ok? The stigma around garlic really is huge! Some professionals will advise against it through no fault of their own – it’s often simply what is taught to them during their education. The controversy all stems from one specific study on garlic, and it’s affects on dogs. Afterall, it’s relatives onion and leek are very much toxic to our pets, so why should garlic be ok when it contains the same active ingredient, allicin? As well as allicin, members of the allium family also contain Thiosulfate. Thiosulfate, in large quantities, can cause a severe type of anaemia in cats and dogs, called Heinz Body Anaemia. If we look at onions vs garlic, we can compare the amount of thiosulfate, and therefore calculate the risk of Heinz Body Anaemia. Onions contain large quantities of Thiosulfate, whereas garlic only contains miniscule amounts, which plays very little to no risk in healthy individuals, and studies were began to work out just how much garlic is safe for our pet dogs. Findings Here So, moving on to the study. The nutrition world was taken by a storm in 2000 when Dr Osamu Yamamoto released a study called ‘Haemolytic Changes Associated with the Appearance of Eccentrocytes After Intragastric Administration of Garlic Extract to Dogs’. You can find the study here. Now, the first point to make, just from looking at the title; garlic ‘extract’ was used. Have you ever baked a cake, using Vanilla Extract? You may notice the extract is extremely concentrated, making it extremely pungent, requiring just a few drips to flavour the entire cake batter! This concept goes for any extract, including that of garlic. The garlic was administered to the dogs in the study in extract form – 1.2mls of this liquid was given to each dog per day for 7 days – likely the equivalent to much more than one would consider giving their dog of anything! More on equivalent amounts shortly. When looking at the health of the dogs in the study, it’s important to note that there was a death rate of 0% – that’s right, a big fat ZERO! No dogs died in the study, nor were there any physical changes to the dogs. When blood tests were analysed under a microscope, despite the lack of symptoms, there was a case of Heinz Body Anaemia. This was the evidence which caused the scientists to make the rather bold statement, that garlic is unsafe for dogs, sending the pet world into panic! Some of the large pet information databases and websites are still under the assumption that garlic is very much toxic to dogs, warning owners to avoid it. Pet food manufacturers were forced to remove garlic from their recipes once this information was released, but further studies were needed to ascertain whether fresh garlic would be safe, since the aforementioned study used the ultra concentrated garlic extract. Let’s take a deeper look at exactly how fresh garlic tolerance levels differ to that of concentrated garlic extract! What Science Has to Say About It As with many preliminary scientific studies, mass panic had set in, opening up opportunities to research the tolerance level of fresh garlic in dogs, after all in unsuitable quantities, anything can be classed as toxic – even water, and we all know water is incredibly important for all living things! When converting the amount of garlic extract that would need to be administered to a medium sized dog for adverse reactions to occur, to the equivalent amount of fresh garlic, the dog would need to consume 35 cloves of garlic every day (or 245 cloves per week!) – not something any owner would dream of doing, we are very sure! Now for the next study by Dr Osamu Yamamoto, titled ‘Acceleration of Superoxide Generation in Polymorphonuclear Leukocytes and Inhibition of Platelet Aggregation by Alk(en)yl Thiosulfates Derived from Onion and Garlic in Dogs and Humans’, published in 2004. This study can be found here. In this study, they used a fresher form of garlic to carry out their investigation, which ultimately found that garlic was in fact good for cardiovascular health, and useful for a
Here at My Pet Nutritionist, Liver Disease is something we help pet parents with quite often. The prospect of living with a dog with liver disease can be a daunting one. But we are here to help put your mind at ease, with this handy blog post packed full of useful hints and tips to supporting your pet’s liver, naturally. The Role of the Liver The liver is an extremely important organ in the body. It plays many roles in the overall health of the pet, including digestion, nutrient absorption, metabolism, detoxification, immunity, and endocrinologically. These roles, all link with one another, much like a large ‘loop’ of bodily functions dependent on the liver. Metabolically, the liver detoxifies fats from the body, and is also involved in the conversion of thyroid hormone 3 to thyroid hormone 4, which we can also look at from an endocrinology point of view. When looking deeper into the liver’s role in detoxification, we see that not only does it detoxify the body of excess fatty acids, but also of drugs, steroidal hormones, environmental toxins, and ammonia (as it helps the formation of urea). In terms of nutrients absorption and storage, the liver is involved in the storage of glycogen, which controls blood sugar levels, and also plays a role in the storage and absorption of Vitamins A, B12, D, E and K, as well as minerals such as iron, magnesium, zinc, and copper. If we look at what the liver produces, we see is produces cholesterol, which is an important precursor to vitamin D synthesis, and production of sex hormones, and it also produces bile, which is used for digestion of food, and also helps keep the gut free from unwanted microbes. Looking at hormone production, the liver produces and secretes four main hormones, or precursors for production of other important hormones. These are: Somatomedin (insulin-like growth factor, essential for regulation of growth of bones and tissues in the body) Angiotensinogen (involved in the regulation of blood pressure and balance of fluid) Thrombopoietin (used by the body to stimulate blood platelet development) Hepcidin (used to block the ability of cells releasing iron, which in turn regulates iron homeostasis in the body) Findings Here Findings Here Findings Here Findings Here Finally, the liver is largely involved in the synthesis of some of the body’s most important proteins, such as: Prothrombin (used in blood clotting) Albumin (plasma protein responsible for controlling the flow of fluids through the capillaries, known as Oncotic Pressure) Globulins (used in immune function) Ceruloplasmin (enables healthy absorption of dietary copper) Lipoproteins (used to transport cholesterol in the body) Findings Here Findings Here Findings Here Findings Here Findings Here What is Liver Disease? Liver disease can be any form of problem with your dog’s liver. Generally speaking, most liver problems in dogs start with an enlarged or swollen liver. Due to the strain on the liver when it is inflamed, liver cells begin to die off, while being replaced by scar tissues – tissues that form after trauma, and can be obstructive if they become too thick. The presence of scar tissues in the liver, cause the structure, texture and appearance of the liver to change. It tends to become firmer – the scientific name for this, is cirrhosis. Cirrhosis is not reversible, and can be a death sentence for the dog, as the liver fails. There can be many triggers and causes of liver disease in pets, including use of some drugs such as selected pest treatments, onset of hepatitis (chronic swelling of the liver), cancer, environmental toxins, infection or sepsis, congenital issues, and even autoimmune disease. Symptoms of liver disease include: Lack of appetite Blood in vomit due to stomach ulceration Jaundice (yellowing of skin, eyes and mucous membranes) Fluid build-up in the abdomen/bloat Excessive urination (polyuria) Excessive water consumption (polydipsia) Diarrhoea Fever Neurologic symptoms Issues with blood clotting There are some changes to diet and lifestyle we can make to help those with liver disease – let’s find out about these! Liver Guard Supporting the Liver Gut Health Gut health may seem like an odd connection to liver disease, however the two can certainly be linked! There’s a group of systems, or axes, which link the gut with the rest of the body, acting as a sort of ‘roundabout’ for the microbiome. You may have heard us mentioning the HPA Axis, the Gut-Brain Axis, and the Gut-Skin Axis; well, the Gut-Liver Axis is another! The main vein involved in the interactions between the gut and the liver, is called the Portal Vein. This is a two way path, through which products derived from the gut are transported directly the liver, and bile, and other liver secretions are transported directly back to the gut to be used in digestion. As the gut microbiome is so incredibly important for prevention, and management of nearly all health conditions, a healthy gut is ever so important. Healthy microbial communities in the gut, make for healthy gut-liver axis homeostasis. Having an unhealthy or unbalanced gut microbiome can lead to exposure to microbes which are pro-inflammatory, causing liver inflammation, and consequently, liver disease. Findings Here To keep the gut healthy, we can tweak the diet, and add supplements – which we will discuss next! Diet As ever, when the body is under inflammatory stress, or has any disease, we need to look at tweaking the diet, to ensure the pet is being fed the most biologically appropriate diet, with the correct nutrition to nurture the body depending on the specific health condition(s) the pet may be facing. A fresh diet would be most suitable, whether that’s raw or cooked. Many dogs suffering with liver problems, may do better on a cooked food instead of raw, but many do just as well on raw! Now, when it comes to different liver conditions, there is no one-recipe-fits-all. Those with liver shunts for example, we would recommend sought advice from one of our team, so we can provide
Here at My Pet Nutritionist, we see a lot of people worried about their dog’s recent blood test results. The Liver Enzyme reading may be higher than expected for a variety of reasons, and could be partly down to the food being fed to your dog. This blog aims to help you gain a better understanding of the value you may have received, and what may have caused it to be high. A Bit About Liver Enzyme Readings When your dog has a full panel of blood tests, performed by your veterinarian, your dog’s liver function is tested. The results will show on the results sheet as values for ‘ALT’, ‘AST’, ‘ALP’, and ‘GGT’. There is a set range of values which denote normal/healthy liver function which are as follows: ALT: 12-118 U/L AST: 15-66 U/L ALP: 20-200 U/L GGT: 0-25 U/L Each reading is the result for a different liver enzyme – read on to learn about each one. Your vet should help you analyse your dog’s results, and offer feedback as to the health of your dog’s liver. Findings Here Findings Here Findings Here What are the Liver Enzymes? As mentioned, each value relates to the levels of a different enzyme. Enzymes help to speed up chemical reactions in the body, and in the case of the liver enzymes as a whole, they are responsible for the production of bile, blood clotting, digestion, breaking down toxins, and helping the body to fight infection. Let’s take a look at the different enzymes tested for in your dog’s liver. Alanine Transaminase (ALT) ALT is an important catalyst for the process involved in the metabolism of glucose and protein, to for pyruvate (major part of cellular respiration) and glutamate (an important neurotransmitter used for memory, mood regulation and cognitive capabilities). When liver cells are damaged, ALT is released into the bloodstream. High amounts of ALT Leakage, means your dog could have liver disease or trauma. Findings Here Findings Here Aspartate Transaminase (AST) AST plays a major role in Gluconeogenesis of the liver, as well as some other tissues and organs. It is a catalyst for the transfer of an amino acid from aspartate to glutamate. Raised AST values can also be caused by leakage into the bloodstream through disease or trauma to the liver, as well as trauma to the muscles in the body, as AST is also found in the musculoskeletal system in mammals. Findings Here Findings Here Alkaline Phosphatase (ASP) ASP is found throughout the body, in the bloodstream. It is the catalyst for the hydrolysis of phosphate esters, leading to the breakdown of proteins in the body, and it is produced not only by the liver, but in the kidneys, intestines, pancreas and bones; it is however, produced mostly by the liver. Findings Here Findings Here Gamma-Glutamyl Transferase (GGT) GGT aids the transfer of amino acids through the membrane of cells, and is also involved in leukotriene metabolism. It is a prominent marker of liver dysfunction, so elevated GGT readings are best to be further investigated as soon as possible! Findings Here Findings Here Liver Guard What Causes Raised Liver Enzymes? While there are various underlaying health conditions which cause raised liver values, including liver disease, hepatitis, cancer, thyroid disease, various myositis diseases (muscular disease), diet can influence your dog’s liver enzyme values. Too Much Copper When there is too much copper in the diet for the individual dog, the dog may develop copper-storage liver disease, scientifically known as Copper Hepatopathy. Copper is an important nutrient to include in your dog’s diet, as it aids the production of energy, and maintenance of blood vessels, and connective tissues throughout the body, however the liver is unable to process large amounts of it, which leads to a build up in the liver, which then has to store it. This damages the liver, causing elevated liver enzymes due to disease. Findings Here Findings Here Low Copper Too Much Vitamin A While Vitamin A is an important part of a balanced diet, essential for ocular health, healthy development, a strong immune system, and reproductive health, supplementing the diet with extra Vitamin A can cause elevated liver enzymes. When looking at nutrient profiles of your dog’s diet, try to use fresh ingredients (fresh fruit and veg, specifically selected, may be the best addition to your dog’s diet), instead of a supplement. Supplements tend to be very concentrated, which could easily tip your dog over their recommended daily intake of Vitamin A – this is called hepatotoxicity. Findings Here Findings Here Findings Here Too Much Iron Over-supplementing iron can also cause hepatotoxicity, which occurs due to iron-poisoning. Having excess iron intake causes raised liver enzymes due to the damage caused by hepatotoxicity, known as hemochromatosis. Findings Here Findings Here Zinc Deficiency Zinc deficiency often comes hand in hand with excess Vitamin A consumption. Some studies suggest that elevated Vitamin A in the blood could be caused by a lack of zinc, not just by over-consumption. Zinc levels are often skipped during testing for various diseases, but are extremely important to investigate. Findings Here Findings Here Findings Here High Carbohydrate Diets Studies show that dogs fed a high carbohydrate diet are more at risk of developing liver disease, and therefore raised liver enzymes than those fed a low carbohydrate diet. One of the roles of the liver, is to maintain glucose concentrations in order to control the metabolism of carbohydrates. If the liver is strained too hard due to being overloaded by carbohydrates, it is at risk of leaking enzymes into the bloodstream, causing elevated liver enzymes. Findings Here Findings Here Findings Here Ketogenic Diets As much as a high carbohydrate diet may lead to leakage of liver enzymes, a low-to-no carbohydrate diet may also lead to the leakage of liver enzymes, as the liver overproduces them. Some conditions do require a ketogenic diet, such as those suffering from cancer, but if your dog is on a ketogenic diet, ensure your dog’s blood is
Yeast is a problem we see very often here at My Pet Nutritionist. Owners often feel they have run out of options with regards to treating the yeast, so this guide has been made with the goal of helping you overcome yeast; you may just see something missing from your routine which could be the missing piece for success! What Is Yeast? Yeast, as we commonly call it, comes in two forms – Candida; a fungal pathogen, and Malassezia; a skin based hydrophobic yeast. Candida makes up a small portion of a healthy gut microbiome, and is naturally found in the gut, and genital tract. While candida is a very normal part of a healthy gut, if the gut is not kept in tip top condition, it can cause problems. In the healthy gut microbiome, there are good bacteria, and there are bad bacteria. The good bacteria keep the levels of bad bacteria in check, which means the bad bacteria aren’t able to wreak havoc! When the gut is impaired the opportunistic fungal pathogen, candida will take hold, and grow. Now we have too much of the ‘bad guys’ and not enough of the good bacteria to fight it off, and so candida takes over! Once candida has taken over, and the gut is not healed, we start to see the typical yeast symptoms in our pets. Malassezia often happens as a result of environmental allergies, as the skin barrier is damaged, allowing for the formation of yeast on the skin. Much like inside the gut, the skin has it’s own microbiome, in which the bad pathogens are kept in check by the good. When the good pathogens diminish, the bad ones are able to take over! This is something we see in a vast amount of customers who come to us with a dog with environmental allergies. Symptoms include: Rusty colour, mainly between toes and paw pads, ears, under the tail, and around the groin and armpit areas. It can occur in other places too, but these moister areas are prime location for it! Repetitive paw licking Licking under the tail area Ear scratching and head shaking Excessively rubbing face and body on walls and furniture Hair loss An unmistakable odour; much like a damp, cheesy smell, or popcorn-like smell Sometimes discharge is apparent in yeast cases More Information on yeast can be found here. Let’s take a look at how we can help our dogs battle Candida and Malassezia! Battling Yeast When dealing with yeast, there are many contributing lifestyle and nutrition factors, which may need to be tweaked a little, or added to combat the pathogens, and repair both the gut barrier, and the skin barrier. Diet As always, here at My Pet Nutritionist, we are very fresh food forward. Feeding a dog with yeast is no different – one of the main steps to battling yeast, is cutting out dry food as much as possible. A fresh, balanced diet would be your best option whether it’s raw, or homecooked using one of our balanced recipes. Why does diet matter for those suffering from yeast? Let’s take a look at the composition and manufacturing process of dry foods, first and foremost. Kibble is high in carbohydrates: generally speaking, most kibbles are between a whopping 30 and 70% carbohydrates! Carbohydrates are sugars – a fantastic food source for yeast! The canine body struggles to digest carbohydrates often found dry foods, which causes gut inflammation. Kibble is ultra processed: excessive processing causes the food to become inflammatory. When the gut becomes inflamed, damage occurs, which leaves the microbiome vulnerable, and causes imbalances as the bad microbes out compete the good microbes. Advanced Glycation End Products (AGEs) are produced during high heat manufacturing and extrusion of dry foods. AGEs not only speed up the ageing process, but they have many other health disadvantages too, one being that they expand the life of yeast. We need to cut out products which produce AGEs when we are battling yeast! Findings Here Why can fresh feeding help combat yeast? You can tweak the diet to ensure there’s no starchy carbohydrates. Less ‘food’ for the yeast! It’s much easier on the gut, as it’s highly digestible! This means less gut damage and less inflammation. There’s no high temperatures or vigorous processing involved, meaning no AGEs form! What do we need to include in a fresh diet for yeast sufferers? Our recipes for cooked foods are already balanced for you! However if you are raw feeding, you will want to feed 80% muscle meat, 10% bone, 10% secreting offal (half liver, half other secreting offal, preferably!) with the addition of omega 3 sources like raw eggs, fish oils and oily fish, and algal oils. Some vegetables may be suitable to be added to the diet of a yeasty beastie, but we need to be very selective, and very careful which ones we pick! High fibre, low starch veggies are ideal, if tolerated – it’s wise to start off by giving a miniscule amount of plant matter, and gradually building up to 10% plant matter. Some options are broccoli, kale, and cabbage. Try to avoid starchy carbohydrate plants such as sweet potato, carrot and squash. Supplements There are so many supplements on the market these days – it can feel quite daunting selecting the most suitable ones for your pet. Some are better than others when it comes to battling yeast. Gut healing: gut healing supplements are very important – in order to regain balance in the gut microbiome, we want the gut to be in a good, healthy, and strong state. Mucilage herbs are our friend here! Slippery Elm, Marshmallow Root and Deglycyrrhizinated Liquorice are all great for this purpose! Gut Guardian Probiotics: probiotics are essential for yeast sufferers, as they help to rebalance the gut microbiome, by out competing the bad bacteria, which in turn will aid the recovery of the skin barrier. Once there are sufficient levels of good bacteria, the ratio
Here at My Pet Nutritionist, we regularly see frequent urination as a sign of illness, stress and other diet related issues. The scientific name for excessive urination is Polyuria, and it often comes hand in hand with Polydipsia (excessive drinking). Read our Polydipsia blog here. Let’s discuss what may cause this! Diet The diet you feed your dog may affect the amount of urine produced. Dogs fed on a dry food diet will require a larger intake of water as their food is lacking in moisture which puts pressure on the kidneys. Wet/fresh food on average is around 75% moisture verses a dry food which is around 8-10% moisture. Similarly, high salt diets and treats will affect kidney function. The kidneys require a good amount of moisture to keep them functioning properly; so the dog will feel thirstier, consume more water and then as a result, produce more urine to be excreted. Illness Dogs may experience polyuria as a symptom of numerous health issues. Polyuria tends to go hand in hand with polydipsia as excessive thirst causes excessive drinking, which in turn causes excessive urination. Cystitis/Urinary Tract Infections (UTIs) A common observation made by pet owners when their dog has a UTI, or cystitis (UTI of the bladder) brewing, is that the dog begins to urinate more often, and in unusual places. This can be tricky to differentiate from adolescent behaviour in younger dogs but is important to rule out if your dog has been urinating in the house, having been fully house-trained previously. A dog will drink more water when experiencing a UTI in an attempt to flush it through the system, which will result in more urine being produced, and the dog being unable to hold it until their next garden visit. If your dog is urinating in unusual places, be sure to collect a urine sample and take it to your vet for analysis. Findings Here Sickness bug/nausea Sickness bugs often cause nausea and/or diarrhoea, which in turn causes a dog to require more liquid. As the dog will have increased their liquid intake, they will also produce more urine. Encouraging a dog to drink more, means they’re less likely to become dehydrated, even if it results in more urination than is normal for that dog. If you’re struggling to get your dog to drink, bone broth is an excellent powerhouse of nutrients as well as moisture –perfect for a poorly digestion. Bladder stones When a dog has bladder stones, they may urinate more frequently than is normal for that dog, producing only a few drops each time.The urine may contain blood, often due to straining, or a secondary Cystitis infection. There are numerous types of bladder stone, and it’s very important to find out from your veterinarian, which type of bladder stone is present. You can then tweak the diet dependent on bladder stone type – check out our bladder stones blog here. Findings Here Findings Here Kidney Disease/Infection Polyuria is one of the most common, and earliest signs of kidney disease. Dogs with kidney disease may also start to urinate overnight. Other symptoms include nausea, weight loss, lethargy, and changes to bowel movements. During the earlier stages of kidney disease, the kidneys become unable to efficiently concentrate urine, causing the dog to drink more; and subsequently urinate more. Kidney infections (scientifically known as pyelonephritis) also cause damage to the inner part of the kidney known as the Medulla, which filters and dilutes urine. When this is damaged, more water is required to successfully dilute the urine; causing the need for more urination. If left untreated, the ability to properly dilute urine decreases. Findings Here Findings Here Liver disease A staggering 50% of canine liver disease cases present with polyuria. Hepatic encephalopathy (the condition when changes in the brain cause liver disease) and liver shunts damage the liver and can cause false signals to be sent back to the brain via neurotransmitters, which causes an increase in the production of a hormone called Adrenocorticotropic (ACTH). Elevated ACTH secretion causes havoc with the tissues in the body, and causes the dog to require more moisture, resulting in the need to urinate more. Findings Here Cushing’s Disease Dogs with Cushing’s Disease usually produce too much of the hormone, Cortisol. As well as being caused by excessive exposure to Cortisol, Cushing’s Disease can be caused by long term use of glucocorticoids – drugs such as hydrocortisone. Like those with Liver Disease, those with Cushing’s Disease have elevated exposure to ACTH, which ultimately leads to increased thirst, and therefore increased urination. Findings Here Findings Here Findings Here Diabetes Insipidus Just like with polydipsia, polyuria is another very common symptom of Diabetes Insipidus. Of course, there are many other things that may cause polyuria, but Diabetes Insipidus is one of the conditions your vet may wish to discuss with you, often once other conditions have been ruled out via various tests. The most common type of Diabetes Insipidus is Secondary Nephrogenic Diabetes Insipidus, and your vet may need to instruct a water restriction to be able to measure the concentration of the urine produced. An estimate of 0.32% of dogs in the UK have diabetes, mostly occurring between the ages of 5 and 12 years. Findings Here Findings Here Incontinence Dogs suffering with incontinence may urinate more frequently, but usually in smaller amounts. This is because the sphincter at the bottom of the bladder is weak, or the messages sent from the brain are abnormal, causing the lack of controlled flow. Incontinent dogs will often urinate in small drips through the day when standing, sleeping, walking or getting up from a laid down position. Incontinence can be due to many factors including early spaying (known as spay incontinence), ageing, or even down to genetics when the part of the brain which controls the coordination of the bladder muscles; called The Pons, has a defect. Findings Here Medications Long-term use of certain medications can cause polyuria, including glucocorticoids, phenobarbitone, and furosemide.
In most cases, a liver shunt is caused by a birth defect. This is known as a congenital portosystemic shunt. But acquired shunts can also occur – this is usually linked to primary liver disease, or a disease involving the normal blood vessels into the liver. We describe the liver as the powerhouse of the body, quite simply because it carries out so many functions, so, is there anything we can do to support it when it’s function isn’t quite up to par? Let’s take a look at whether we can support a dog with a liver shunt. What Does The Liver Do? The liver processes blood and the substances found within it. In a healthy animal, blood draining from the intestines passes immediately through the liver for nutrients to be processed and for toxic compounds to be removed. The blood then re-enters main circulation. What is a Liver Shunt? In an animal with a portosystemic shunt (liver shunt), a significant volume of blood bypasses the liver, enters main circulation and heads to the heart where it can be pumped around the body. As the blood being pumped around the body is technically unfiltered, toxic compounds can build up. In addition, the liver is unable to break down nutrients or regulate the body’s energy balance. Signs and Symptoms of a Liver Shunt: Stunted growth Poor muscle development Abnormal neurological behaviour – disorientation, staring into space, circling or head pressing, seizures Drinking/urinating too much Vomiting Diarrhoea Lethargy In both cases of congenital and acquired, reduced blood flow to the liver also results in atrophy which subsequently affects function. But the liver is a rather unique organ, it is the only one that can regenerate, therefore appropriate intervention and management is essential. Liver Guard Considerations to make for the dog with a liver shunt: Diet The conventional concern with many liver issues is protein intake. When protein is broken down in the body, left behind is ammonia. The liver plays a key role in metabolising ammonia ready for it to be excreted by the kidneys into urine, but when blood flow bypasses the liver, ammonia builds up in the blood and enters systemic circulation – this is what leads to many neurological issues alongside poor liver function. Traditionally, dietary management has included protein restriction to reduce ammonia absorption from the colon, but more recently it is considered that colonic absorption is only significant in those fed poor-quality diets that contain poorly digestible protein. In addition, it has been established that those with chronic liver disease may develop muscle wasting from being in a long-term catabolic state – with low protein diets leading to increased muscle protein catabolism. Findings Here We would advocate a fresh-food diet, with highly digestible protein sources. The general school of thought is 2g of protein per kg of body weight. Beneficial proteins to feed in liver disease include eggs for the most bioavailable protein and choline content, poultry and a little fish such as sardines, salmon and cod. Fats such as omega-6 and omega-3 in 4:1 ratio are important in liver conditions. Moderate amounts of hemp oil, phytoplankton (offering DHA and EPA) and fish, both whole and in pure oil source may help to protect the liver and reduce systemic inflammation and inflammation in the liver. Detoxification The liver neutralises a range of toxic chemicals, both those produced internally (waste from used hormones or neurotransmitters for example) and those from the environment, like air pollution, pesticides and food additives. It does this by filtering the blood to remove large toxins, synthesising, and secreting bile and lastly enzymatically disassembling unwanted chemicals found in the body. If its function isn’t up to par, toxins can start to build up. Enzymatic Detoxification This enzymatical detoxification occurs in three phases. Phase I directly neutralises chemicals and changes them into new metabolites. These are then processed by phase II enzymes. This is known as the conjugation phase, which in short, liver enzymes attach small chemicals to the toxin. There are many ways in which this is done, it all depends on the type of chemical the liver is trying to manage. Phase I results in high levels of reactive oxygen species so antioxidant levels are key in modulating potential damage. Does My Dog Need Antioxidants? Liver Guard Beneficial Additions: Broccoli contains glucobrassicin, the glucosinolate precursor of indole-3-carbinol (I3C) and subsequently Diindolylmethane (DIM) which is attributed to supporting phase one of the liver detoxification. Berries and cranberries whole and in extract contain anthocyanins that demonstrate hepato-protective abilities. An experiment found that antioxidants commonly found in berries slowed the development of lesions and fibrosis, the development of scar tissue, in the livers of rats. Phase II is nutrient demanding and sufficient levels of key vitamins and minerals like vitamin A, C, E, B1, B2, B3 and iron are essential. There has also been data to suggest dandelion amongst others can support the enzymatic detoxification pathway too. Phase III is the elimination phase. For optimal excretion of toxins through the digestive system, gut health is vitally important. Maintaining the mucosal barrier is key for gut health along with supporting motility. It’s important to include a range of functional ingredients in your dog’s diet that can lubricate the digestive tract, promote regular motility, aid elimination and support the microbiome. Prevention of absorption through trapping of potential toxins is also an effective way of mitigating toxin exposure and this is a key feature of many clay products. 7 Reasons to Use Clay In addition, some fibre helps to speed up colonic transit and prevent constipation. This reduces the amount of toxins absorbed from the colon and circulated into the system for the liver to deal with. 7 Foods To Add Fibre To Your Dog’s Diet The most important thing to do to support detoxification is to avoid exposure in the first place, so consider how much you and your dog are exposed to: Pesticides Heavy smoke Phthalates Mould Medications like steroids, antibiotics, and painkillers Heavy metals Cleaning
It is thought there is over 300 recognised breeds of dogs around the World. The American Kennel Club recognise around 190 of them, and the UK Kennel Club recognise 221. For those of us who have a preference for a certain breed we may fondly discuss our love of the Labrador’s happy-go-lucky nature or the trainability of the poodle. It is clear there are breed differences, which suggests a genetic blueprint of certain traits and characteristic. We also know there are genetic predispositions to certain health issues in various breeds. But would you be surprised to learn that there may be breed differences in clinical measurements? A group of researchers, hoping to establish genetic differences in clinical measurements in humans decided that dogs most closely resemble human parameters and so set out to test eight different breeds for 40 clinical markers. Findings Here This is what they found. For the majority of clinical markers, the researchers couldn’t find any significant genetic variants, but for three, they did. Alanine transaminase: ALT ALT is one of the more commonly known liver enzymes. ALT level in blood is used for the diagnosis of liver disease and injury in human and veterinary medicine. Researchers found a variant (SNP) on the gene known as GPT which codes for ALT. A causal variant linked with this SNP could increase expression level of GPT, which would lead to the production of more ALT protein. Belgian Shepherds, Cavalier King Charles Spaniel, Doberman, Finnish Lapphund, and Newfoundland were breeds identified with a significant variation on this gene compared to other tested breeds, suggesting they may have a higher-than-average ALT level as standard. Additional data has suggested that elevated ALT doesn’t lead to metabolic disease per se and in fact metabolic disease is what leads to elevated enzymes. Therefore, it’s essential to consider test results in context and alongside other results, signs, and symptoms. What Could Cause Elevated Liver Enzymes in My Dog? Fructosamine Fructosamine is a stable condensation product of glucose with serum proteins. It is used as a biomarker for diagnosing and managing diabetes because fructosamine reflects the average blood sugar concentration over the preceding 2 weeks. The researchers found variations in the gene which codes for this protein in the Finnish Lapphund, German Shepherd and Newfoundland. Again, it would be an important consideration to make when monitoring these test results over a period of time, in light of any correlating signs and symptoms. The last marker is one that is particularly interesting. Stress During Physical Exam The researchers identified an experimental-wide association with stress during physical examination at chromosome 1. Two breeds, Cavalier King Charles Spaniels and Dachshunds were the most significant. Dogs with the A allele of BICF2P1232291 showed more stress during physical examination. Whilst genes are fixed, we can often influence their expression and in this case, we can also mitigate stress in our dog’s life to regulate that overarching response. If you are planning a visit where your dog will need a physical examination: Limit stress before the visit, Engage in calming and enriching activities to activate that parasympathetic nervous system, Consider the use of a thunder jacket or similar, Allow your dog to decompress after the examination – again offering activities to activate that parasympathetic nervous system (chewing, enrichment, sniffing etc.) What Does All This Mean? This data suggests genetic variations in three clinical markers in certain breeds. However, these researchers only tested eight breeds. It would be interesting to establish how the data may change when testing additional breeds, especially when there are so many around the world. We know there are genetic glitches which contribute to the development of certain health issues, like the filaggrin mutation in skin health, or glitches in zinc absorption in certain sled dogs, but this information further highlights how complex our pet’s health issues truly can be. Can Genes Result in Poor Skin Function? Why Zinc is Important for Your Dog If you feel overwhelmed by your dog’s health issues, then please check out our services to see how we can help. Thanks for reading, MPN Team
