A global infection of both humans and animals, leptospirosis is on the tip of most owners and dog professional’s tongue. Caused by the pathogen icleptospira spp. it is a major zoonosis, with infection acquired from wild and domestic animals. Canine leptospirosis presents very similarly to the syndromes presented in other species with hepatic, renal and pulmonary ramifications. In short, it’s pretty rough, but vaccine induced immunity is restricted to serologically related serovars and is generally very short-lived; therefore, needing annual revaccination. If there are more than 230 serovars belonging to at least ten pathogenic species, does the vaccine even pose benefits? Or do the risks outweigh them? We are going to look at the science and explore both sides to this story. Fancy coming along for the journey? Leptospirosis is characterised by fever, jaundice, vomiting, diarrhoea, renal failure, haemorrhages and ultimately death. However, for those who recover, they may become asymptomatic renal carriers for extended periods and shed infectious leptospires into the environment. This is a large source of infection, as rats can be carriers but do not show signs of infection. Whilst treated dogs can shed leptospires, so can vaccinated dogs. This raises the first red flag; is this potentially increasing exposure? Most signs of leptospirosis become apparent in the first week after infection; younger dogs, less than 1 year of age tend to get the most severe forms of leptospirosis and 87-100% of infected dogs will have some degree of renal implication. There do appear to be different clinical parameters of the infection: Peracute Disease: super-sudden onset which usually affects younger dogs with an overwhelming exposure. The large amount of toxin causes rapid death before the kidney or liver disease even occurs. Acute Disease and Subacute Disease: this is the classic form which manifests as fever with bruising and bleeding, general muscle pain and painful abdomen from kidney and/or liver disease. There may be jaundice and inflammation in the eyes. Chronic Disease: recurring fevers, chronic hepatitis, chronic kidney disease, uveitis, poor appetite and weight loss. However, leptospira interrogans sensu lato is sensitive to doxycycline which is a readily available antibiotic. Leptospires are cleared from the blood within 24 hours of starting antibiotics. But it does take around 7 days to clear from the urine. Prognosis, depending on organ damage is 80-90% with appropriate treatment. There are, however, other serovars, like the pomona which is associated with more severe disease and in severe kidney cases, dialysis can be required which is often limited. So, whilst treatment is largely effective, if started soon enough, there was clearly enough concern to develop a vaccine. Vaccination against leptospira interrogans sensu lato is available for the seravars canicola, grippotyphosa, pomona and icterohaemorragiae. Some vaccines coverall four serovars, whereas some cover two of the four. This is where you will recognise the common lepto two or four vaccine. Vaccination against canicola and icterohaemorragiae has been traditional for dogs and vaccination overall, has been seen to reduce the severity of the disease, but will not prevent infected dogs from being carriers. Note, it supposedly reduces severity, it doesn’t necessarily prevent occurrence. The leptospirosis vaccine was soon associated with a higher chance of vaccine reactions. This is a result of human research into leptospirosis. In the U.K. in 2014 , over 2000 reports of Novibac L4 adverse reactions have been reported to the VMD (Veterinary Medicine Directive) and around 120 suspected deaths related to vaccinosis. In addition to this, data suggested that the severity of the disease was associated with the intensity of the immune response. In short, the more intense and early the response, the more severe the disease. Findings here If our immune system, and our dog’s, is primed to take out antigens and protect, why does a more intense response seem to make things worse? An intense immune response induces a high level of inflammatory cytokines which can result in severe tissue lesions. Immunity is like the porridge in Goldilocks. It can sometimes be too cold (lacking) and sometimes too hot (overzealous). Ideally, we want it, just right. There are many things that affect immune responses, in the case of lepto, a more intense response was associated with previous infection. Fever was induced by virulent injection in previously immunised rabbits whereas non-immunised rabbits exhibited no fever after injection. So, in this case, the immunised rabbits fared poorer than non-immunised rabbits. See where we might be going with this? So we are vaccinating to potentially reduce, not prevent the severity of infection but here it appears those rabbits immunised, had a more severe reaction to exposure. But, stress, nutrition and the environment can all affect immune responses too. So too, can genes. This can help explain why some animals are more, or less susceptible to pathogens (or vaccines) than others. And explain the age-old statement, but my dog was fine! It therefore raises no eyebrows when reports appear of clinical leptospirosis in numerous dogs when they had previously been vaccinated. You’ll remember this from earlier, when it was deemed to reduce severity, not necessary prevent occurrence. This was however, associated with vaccine type. In short, the dogs were vaccinated against only two of the many pathogenic serovars. So, in walked Lepto 4. But these new vaccines were associated with further increases in vaccine reactions, not limited to local swelling or hypersensitivity, but including cardiac abnormalities. Specifically, heart murmurs appearing between first and second vaccination. Findings here What is particularly interesting in studies exploring the use of lepto 4 vaccines, is that dogs demonstrated antibodies to serovars not vaccinated against. Researchers have therefore concluded that natural exposure (not vaccine exposure) to serovars provide positive titre results. Not only that, but in cases of vaccinations up to 1745 days previously, some dogs still demonstrated antibodies. This raises a question around the need for such frequent booster vaccinations. The take home from this particular study was “seroconversion following vaccination differed considerably among individual dogs.” Yet they still concluded that, “in the light of the high incidence and
Anxiety…the word that gets 337,000,000 hits on google. Many of us and our dogs would say, around that many things make us anxious in any one day, but anxiety for the dog can sadly be very life-limiting. Common signs include panting in the absence of exercise, pacing, salivating in the absence of food, inappropriate vocalisation, hyper-arousal, or lethargy and repetitive or compulsive behaviour. Not only that, but there are recognised cases of separation anxiety in the dog where they will dig at exit points, toilet inappropriately and the above behaviours become worse when separated from their guardian. Causes of anxiety are vast, what some dogs will find exciting, others will find stressful. This is where a better understanding of anxiety lies. In humans, anxiety is defined as a fear or worry, whereas stress is a response to a threat or situation. In the dog, if we consider separation anxiety, whilst dogs may respond to the trigger of you picking your keys up, or getting your coat, they exhibit a stress-response. Seeing as bonfire night is upon us, we thought we would talk about how to support and modulate this stress response. Stress is a response in the autonomic nervous system. The sympathetic nervous system primes for flight or flight. The parasympathetic nervous system then comes along to balance it all out, and primes to rest and digest. Whilst this is a very generic overview of the stress-response, there are many processes that are going on, on the inside. To this end, certain nutrients can support and modulate stress responses and help to maintain a balanced system. Magnesium Often noted as the ultimate chill pill, magnesium is an essential nutrient that many are deficient in. Its low levels are regularly established incases of depression in humans, so it is clear it plays a role in mood modulation and the stress response. Findings here Magnesium affects a number of neurotransmitter systems. Firstly, it inhibits excitatory neurotransmitters. Excessive excitation can lead to the death of brain cells, which affects the overall structure and functioning of the brain. Magnesium also acts as a cofactor in the serotoninergic system. As we know serotonin is the happy chemical, and low levels of magnesium are regularly linked to low serotonin levels. Not only that, but magnesium excretion is increased during times of stress. Catecholamines and corticosteroids enhance the shift of magnesium from inside the cell to outside of the cell leading to increased urinary excretion. In turn, low magnesium levels increase the release of stress-associated hormones. This unfortunately creates a cycle of a reduced resistance to stress. Magnesium is found in leafy greens, nuts and seeds. The ones packing the highest punch are spinach and pumpkin seeds. Magnesium is also necessary for calcium absorption, so balancing these levels is key. High levels of calcium increase the need for magnesium. High dosages of vitamin D can also induce magnesium depletion. As an aside, magnesium competes with fluoride in the body and will decrease absorption, minimising the impact of fluoride in the body. Knowing that magnesium is a key player in many of the systems necessary for balanced mood and can be depleted further in times of stress, it pays to add magnesium rich foods to your dog’s diet. L-Theanine An amino acid found in tea leaves; its relaxing effects have been noted in humans for a while now. This is appearing to be true for our canine companions too. In mammals, L-Theanine can cross the blood-brain barrier within an hour after administration. It appears to remain in the plasma and brain for several hours after. L-Theanine isseen to facilitate the generation of alpha waves which are indicative of a relaxed but awake and alert state. L-Theanine helps regulate the usual stress responses like increased blood pressure, heart rate and cortisol secretion. In dogs, L-Theanine treatment has been seen to reduce anxiety scores during storms in fear of humans. Findings here There is also evidence for L-Theanine improving cognitive function and performance in test situations. Findings here It is thought that because of its similarity to glutamate, it can interact with the same receptors, therefore playing a role in neuroprotection against glutamate toxicity. There are also reports of increased GABA activity in the brain following L-theanine administration and we know that GABA is the brakes of the brain. Findings here Green tea contains the highest L-theanine content, and in moderation is perfectly safe to offer to your dog. Alternatively, there are a number of L-theanine supplements available. Findings here Vitamin D Every tissue in the body has vitamin D receptors, but it is the ones in the brain we are most interested in. Vitamin D activates genes that regulate the immune system and release neurotransmitters. In humans, vitamin D receptors are found in the same brain regions that are linked with depression, so we know it has an impact on mood; seasonal affective disorder ties in with this. It is thought that vitamin D plays a role in calcium balance in neurons, which helps to balance excitatory and inhibitory pathways in the brain. Not only that but vitamin D is linked to the regulation of nerve growth factor which is essential in neuronal survival. Offspring of vitamin D deficient mothers often experience learning and memory problems with altered grooming behaviours, and we know that grooming in most mammals is calming and comforting. Findings here The long and the short of it, vitamin D deficiency is regularly noted in cases of anxiety. Findings here Dog’s don’t have the same ability to synthesis vitamin D from the sun as we do, so they rely solely on dietary sources. Sources of vitamin D include oily fish, red meat, liver, and eggs. There are several health issues that affect absorption of vitamin D, like IBD and exocrine pancreatic insufficiency along with having a low-fat diet. Supplementation is an option but being fat soluble be mindful of levels. Magnesium assists in the activation of Vitamin D, so ensure adequate levels of Mg before you
Whilst carbs are generally demonised in human and pet health, if you want to reap the rewards of fibre, you’ll have to play fair with carbohydrates. So, let’s look at carbs for what they really are. A carbohydrate is a molecule made up of carbon, hydrogen, and oxygen, which is why you may often see them noted CHO. Their primary function is to provide energy. Carbohydrates are made up of three components, fibre, starch, and sugar. Sugar is a simple carb. Having fewer molecules to digest and breakdown, it sends an immediate burst of glucose into the blood stream. This is the one that tends to cause a ruckus. Fibre and starch, however, are complex carbs, having longer chains of molecules. Starch takes longer to digest, having a more gradual effect on the body and fibre is a non-digestible complex carbohydrate. So, whilst fibre possibly doesn’t get the attention it deserves, and carbohydrates are routinely demonised, the heath benefits are often overlooked. Fibre, you may be surprised to learn, can be a key player in maintaining absolute gut health and supporting anxious behaviours. 1) Fibre to support your dog’s gut barrier If fibre and resistant starch can’t be digested, what happens to it? It gets fermented by the bacteria living in the gut. This produces short-chain-fatty acids, also known as SCFAs. The most common SCFAs produced are acetate, butyrate and propionate and they all have unique roles. They provide fuel for intestinal epithelial cells, which strengthen the gut barrier and butyrate is known for its role keeping the junctions of the barrier nice and tight. Not only that but SCFAs are able to stimulate mucus production, which is vital for creating a barrier between the external environment and the underlying gut epithelial layer. Mucin production plays an important role in protection from harmful pathogens and immunity. Findings here 2) Fibre to support your dog’s well-bein As you have seen, non-digestible fibre gets fermented into SCFAs in the gut. SCFAs also exert effects on the brain. Not only have all examples of SCFAs been found in the brain, suggesting they can cross the blood-brain-barrier, they appear to modulate neurotransmitters and neurotrophic factors. Neurotransmitters are chemical messengers used by the body’s nervous system. Acetate has been shown to affect levels of glutamate and GABA. Glutamate is an excitatory neurotransmitter and is involved in virtually every major excitatory brain function. GABA is the brakes; it is an inhibitory neurotransmitter. GABA facilitates sleep and reduces both mental and physical stress, creating a calm mood for your dog. In the same strand, it seems all SCFAs can affect levels of tryptophan which is the enzyme involved in the synthesis of serotonin and we all know that serotonin is the happy chemical! Generally, the inclusion of dietary fibre has been deemed a highly appealing approach, which is simple and relatively low risk if you are looking to help support your dog’s mental well-being. Findings here 3) Fibre as a prebiotic for your dog Here is another word you may have come across, but along with probiotics and synbiotics, not really understood which one is which, or whether either even does anything! Well, prebiotics were first defined as “non digestible food ingredients that beneficially affect the host by selectively stimulating the growth and/or activity of one or limited number of bacteria in the colon, thus improving host health.” So, possibly without even knowing, if you included non-digestible fibre in your dog’s diet, you were likely including prebiotics already. All prebiotics are fibre. But not all fibre is prebiotic. Prebiotic substances have demonstrated the ability to manipulate the gastrointestinal ecosystem of the dog, improving the composition of their microbiota and overall improving immune system function in dogs. Short-chain-fructooligosaccharides and oligofructose seem to modulate the intestinal microbiota and aid absorption of certain minerals, whereas mannooligosaccharide exhibits a positive effect on immune system function. Yet is it noted that supplement studies are carried out on healthy dogs; little evidence exists considering the role in canine disease. That said, there are a range of foods that contain naturally occurring prebiotics including dandelion greens, berries, bananas, flaxseed, apples, carrots, asparagus and of course mushrooms! 4) Fibre for your dog’s heart Cardiovascular disease is an inflammatory disease and diet is often considered the cornerstone for CVD treatment. Many studies have demonstrated that high amounts of dietary fibre can significantly reduce the risk of CVD. It is thought that fibre reduces cholesterol and fatty acid absorption and reduces glucose absorption along with decreasing insulin secretion. SCFAs, which are fermented from dietary fibre, also have anti-inflammatory properties and inflammation is central to complications associated with CVD. Findings here 5) Fibre for your dog’s overall health Dietary fibre adds bulk to the stool, which can alleviate cases of constipation. Not only that, but healthy bowel movements are essential to anal gland health in the dog. On its journey, dietary fibre attracts water and turns it to gel during digestion, this not only slows the absorption of glucose but can trap potentially harmful substances. In the same strand, it can speed the transit of food through the digestive system which facilitates regular bowel movements. Findings here Commonly Used Fibre Although fibre is generally an umbrella term, there are fibres within fibres. Cellulose consists of glucose units bound by linkages that can only be broken down by microbial enzymes, those found in the colon. Cellulose is an effective stool bulking agent. Pectins are found in the skins of fruits, being water soluble and rapidly fermentable. Gums are viscous and sticky polysaccharides found in the seeds of plants; they tend to have a variable fermentation rate. Psyllium husk is a form of soluble fibre, it contains mucilage which swells when in contact with fluid, forming a gel. Psyllium can help to improve faecal consistency. Fructo-oligosaccharides are polymers than contain up to nine sugars. FOS enters the colon intact and then is fermented by bifidobacterial and lactobacillus. FOS is fermented into SCFAs. This fermentation also reduces intestinal pH which can inhibit the growth
Traditional Chinese medicine focuses on healing the root cause of disease; encompassing a range of modalities from herbal medicine, mind-body exercise, acupuncture and of course nutrition. Nutrition encompasses food energetics which are based on the idea that certain foods have certain profiles and can subsequently be used to change the profile of the body. Yin energy is cold or cool, and there are certain foods which have cooling properties. Yang energy is warm or hot, and there are certain foods which are warming. There are also neutral foods,which are thought to have little impact on body profile. It is also thought that flavours can act upon certain organ systems and therefore create a desired health benefit. Not only that, but TCM also advocates a seasonal approach to good health. Creating a holistic view of health, it is easy to nod in agreement with many of the TCM ideas, so let’s explore them in a little more detail. Yin and Yang Yin Yang theory forms the basis of TCM; the idea that balance is key. When a deficiency exists, it should be toned up. When an excess exists, it should be reduced. If there is too much heat, it should be cooled. When there is too much cold, it should be warmed. If dampness is present, it should be dried and so on. Yin and Yang is also assigned based on heat signs. Heat and cold can be both deficient and excess; the goal is to be in harmony. Generally speaking, active, young, and outgoing pets are described as yang. Whereas older, quiet, and shy pets are described as yin. Some animals will self-regulate, the older quiet yin cat may choose to sleep in a warm window, whereas the young yang,excited puppy might jump in the water to cool off. However, we can help yang animals remained balanced by adjusting the environment. For the yang pet, provide cooling environments and foods. Include plenty of shade, air conditioning,fans, and misting. Offer fish, turkey,banana, duck, celery, kelp, spinach and broccoli. For the yin pet, provide warming environments and foods; space to sunbathe, heaters and blankets. Offer mutton, deer, chicken, ginger, chicken liver, squash, and pumpkin. Maintaining the yin-yang balance is key to ultimate health and TCM dictates that its disharmony is the basis of all disease. Yang Excess Yang excess is produced by the invasion of excessive heat, yin us unable to counteract the warming properties so an excess heat condition appears. Treatment requires the heat to be dispelled. Clinical signs: Acute onset Short course Younger age No general weakness Hyperactive High fever Red or purple tongue Strong and fast pulse Yin Excess Yin excess occurs when there is an invasion of excessive coldness. Clinical signs: Acute onset Short course Younger age No general weakness Pain Swelling or oedema Loose stool Pale or purple tongue Strong and slow pulse Yang Deficiency Yang deficiency occurs when yang is lower than normal, but yin is at its normal level. The warming properties of yang are insufficient to equalise the cooling properties, resulting in a cold condition. Clinical signs: Chronic onset Long course Older age Coldness at extremities Edema Loose stool Urinary incontinence Chronic pain/weakness Weakness in rear limbs Infertility Pale tongue Weak and deep pulse Yin Deficiency Yin deficiency is when yin is lower than normal, but yang remains stable. This heat condition is named a false heat. Clinical signs: Chronic onset Long course Older age General weakness Thirsty Lower degree of fever Restless or anxious Prefers cool Red and dry tongue Thready and fast pulse These patterns are then used, by a qualified practitioner, to classify clinical conditions and develop a treatment plan. TCM for Itchy Dogs Whilst the clinical manifestation of skin issues overall becomes quite complex in TCM, the general thought is that most conditions are heat invasions, with damp elements and yin deficiencies. When presented with seasonal allergies, eczema, itching, erosions with pus, alopecia, hot spots and dermatitis, a cooling diet is recommended. In cases of geriatric dryness or dandruff and chronic skin conditions a neutral or cooling diet is recommended. Cooling meats include turkey, ocean fish, rabbit, and white fish. Cooling vegetables include spinach, broccoli, celery, kelp, cabbage, cucumber, and melon. Sesame and flaxseed oil are also cooling. Low Fat Fish Neutral meats include pork, bison, duck, beef liver, pork liver, goose, mackerel, sardines, herring, salmon, and tuna. Neutral vegetables include carrots, green beans, peas, and shiitake mushrooms. Olive oil is also classed as neutral. If we are to consider foods to drain damp, they include beef, beef kidney, lamb kidney, mackerel, and sardines. Along with parsley, lettuce, parsnip, pumpkin,and seaweed. TCM for Skeletal Health With many skeletal issues facing dogs, it is no surprise we want to know if we can use food energetics to our advantage. What is particularly interesting, is that cases of rheumatoid arthritis can present as either hot or cold. The cold pattern is described in humans (dogs have yet to learn how to speak) as cold feelings in the limbs and joints, stiffness, or pain in a joint or muscle which is relieved by applying warmth. Symptoms increase with exposure to cold. The heat pattern is associated with hot, red, and swollen joints with severe pain generally relieved by applying cold. Although diagnosed across the board as rheumatoid arthritis, both hot and cold patterns exhibit different biological markers. Both patterns share the same expressed genes, but they appear to have different signalling pathways. T cell proliferation and the secretion of pro-inflammatory cytokines appear to be increased in hot pattern RA patients. There also appears to be more severe collagen destruction in hot pattern RA too. Cold pattern RA appears to have a higher rate of protein and fat mobilisation demonstrating a more obvious muscle breakdown. Cold pattern patients also demonstrate a reduced hypothalamic-pituitary-axis function which is associated with a decreased stress response which goes someway to explain the higher fatigue level reported in cold pattern RA. Findings here RA, to most is considered
When looking at the nation’s dogs we have a major issue on our hands, a topic that can stir up emotive responses from owners and something that animal professionals may have a tricky time addressing… OBESITY From an owners perspective, they only want the best for their dog, and to be told their dog is overweight can be hurtful to hear. Your animal professional hasn’t seen those puppy dog eyes, peering over the plate looking for crumbs. Or the look you get when you need to nip out and you’re compelled to give them a treat as compensation. From an animal professional perspective, we see that overweight dog walk into our clinic and our heart sinks. Desperately wanting to tell you the list of byproduct diseases of obesity and give you a long list of things to change for your dog’s health. Instead, we softly mention they could stand to lose a little weight, to be met with a look of shock and disheartened words. Please don’t think we are here to make you feel that you’re not doing your best, we are here to guide you and want you to have the most time with your beloved pet. As much as it may be a tough conversation to have, we as animal professionals have a duty of care to animals in our clinic, and weight management is something that we need to be discussing more. For us it isn’t simply a case of sprinting around the park and cutting back portion sizes, there is so much more that we can do and it starts by inspecting what is in the dog’s bowl. Say for example your dog is on processed kibble, cutting back portion size when looking at the calorie deficit model for weight loss may have some impact. However,with your older dogs they will reserve reduced energy levels caused by food restriction, meaning weight loss can be very slow or stationary. Most processed dog food has a high percentage of carbohydrates, and this is where the issue lies. When a high volume of carbohydrates hit the GI tract, this causes a rapid increase in blood sugar and insulin levels. If the body cannot use this energy quickly enough, the leftovers get shunted into fat cells held in adipose tissue. Now going on a slight but relevant tangent, arthritis is a byproduct of obesity. Arthritis is an inflammatory disease affecting the joints and shows a higher prevalence in overweight dogs. Findings here If adipose tissue has a larger surface area caused by obesity, this increases the amount of pro inflammatory adipokines. So not only does additional physical pressure cause inflammation, but inflammation responses are increased tenfold with adipokines also jumping on an arthritic joint. Findings here So we know that carbohydrates increase blood sugar and insulin and lead to a cacophony of different issues, of which I’ve briefly discussed one. How can we look to combat this and get the best from our dog’s health, well for a start you can cut the carbs or at least look to reduce them. At MPN, we are hugely passionate about species appropriate diets and have seen incredible progress with pain management, all from just swapping to fresh foods. Even if you can’t make the leap to fully raw feed or fresh feed, there is plenty of middle ground that you can address, that will help towards a healthy life for your dog. Supercharging the bowl Whether you’re a keen raw feeder or just wanting to liven up the bowl by adding in some fresh, there is plenty of choice. Focusing on musculoskeletal health, our first port of call is adding things high in glucosamine and chondroitin. Both are complex sugars found within the structures of cartilage. Studies have indicated that these have a positive effect on pain management and ROM increase associated with Osteoarthritis. Findings here If you have compromised cartilage, you can heal with cartilage and these are super easy to source for your dog’s bowl, from bone broth, raw beef trachea to green lipped mussels (GLM). By supporting the joint health of an overweight dog, we can encourage further ROM and decrease inflammation, all working towards weight loss, there is a lot of research around turmeric (curcumin) and ginger (gingerol). Findings here Other favourites of ours for targeting joint inflammation are ACV, chamomile, fresh small fish and sunflower seeds. There is a huge amount of free radical damage (oxidative stress) created from excess adipose tissue and so looking at antioxidants to support this can be helpful. A diet high in colourful, fresh vegetables and Vitamin C can be fabulous in this instance. Findings here Lifestyle management If your dog is overweight, their joint health is likely already under pressure, but we can add some simple changes in place to reduce this strain. Start by increasing the length of your dog’s exercise, but reduce the pace. By having your dog run around the park doesn’t necessarily mean they will burn off more calories. High-impact activities will increase inflammation responses and then facilitate a pain response. Count your dog’s steps, have them on a lead next to you and go that bit further with less pressure, rather than seeing them flail around on the horizon chasing a squirrel. Be present and enjoy the walk with them, as much as it’s good for your dog, it’s good for you too! Oh no, here comes the fun police… ball flingers. Ball flingers can cause such horrific damage to your dog’s musculoskeletal structure over time, from huge repetitive stress crashing through the body when they come to a stop. If you’re not ready to put the ball flinger down, maybe drop the amount of times you throw it, or ensure warm up and cool down regime, the aim being to reduce inflammation and injury. Even things like ramps into the car and little stairs for the sofa make a tremendous impact on keeping inflammation and strain at bay. Therapies If your dog is
Joint issues like rheumatoid arthritis, osteoarthritis, spondylitis, hip dysplasia, lameness, luxating patellas or other inflammation and/or damage, can occur for a high proportion of dogs. We usually put it down to age, being overweight, activity and breed but joint issues do not discriminate. Around 1 in 5 dogs, only over the age of 1 can experience joint issues and this raises significantly over the age of 4. Joint supplements are one of the most searched for supplements for dogs and so I wanted to touch on this as there are the good, the bad and the ugly. I don’t want to talk about brands but how to choose a good joint supplement. Here at MPN, we don’t get sponsored to recommend brands as we wish to remain impartial. There are some professionals who have been recommending brands due to incentives. It may well be those products are good, but how do we know that? So the best way to tackle this, is to understand how to best pick a joint supplement. There are five major corner stones to joint health, 5 major physiological processes and impactions that affect the joint. These are digestion, inflammation, degradation, oxidation and joint lubrication. We call it the 5-TIONS and if we understand what is happening and what ingredients help with those physical elements, then we can choose wisely. When looking at joint health you need to consider all mechanisms responsible for the disease and then how to select ingredients to support those processes. · Digestion; for a number of reasons, digestion can become compromised and the mucosal wall, the one cell epithelial, can become less integral and become ‘leaky’. A damaged intestinal lining is permeable, allowing larger, undigested food particles and intestinal microbes to escape into the bloodstream. The food particles that leak into the bloodstream are viewed by the immune system as foreign bodies, causing an immune system response. The microbes that escape into the bloodstream can also cause an immune system reaction. These microbes are often gram-negative gut bacteria whose outer membranes contain molecules called lipopolysaccharides(LPS). Lipopolysaccharides trigger the immune system. Gut microbiota also has a role to play in the function and aetiology of RA (Rheumatoid Arthritis). · Inflammation; it’s generally the inflammation and rubbing of joints that create pain and stiffness. Immune responses to allergens or stress can create an inflammatory cascade, known as the cytokine inflammatory cascade that can create a systemic inflammation, affecting joint health. An activated immune system produces antibodies that can travel in the bloodstream and create an inflammatory response in other parts of the body, including joints, leading to arthritic pain and swelling. · Degradation; is the main reason for the breakdown of the joint matrix. Degenerative joint disease, often osteoarthritis (OA), is a common “wear and tear” disease that occurs when the cartilage that serves as a cushion in the joints deteriorates. This condition can affect any joint but is most common in knees, paws, hips, and spine. The joint matrix and connective tissue need to be supported by components that replicate the structure of joints, naturally. · Oxidation; increasing evidence suggests that oxidative stress may play a key role in joint destruction and in particular, rheumatoid arthritis (RA). Free radical damage can create more degradation and inflammation, so looking to support this process with natural antioxidants to help create a protection and further degradation, is essential. · Joint Lubrication; synovial fluid within the joint matrix is incredibly important to support cushioning and movement. Alterations in synovial fluid (SF) lipid composition have been linked to both osteoarthritis (OA) and rheumatoid arthritis (RA). This needs to be supported in a joint formula when choosing your product. What ingredients can be considered for the 5-TIONS DIGESTION N Acetyl Glucosamine: is a wonderful form of glucosamine that has an affinity to the healing of the gut mucosa, healing ‘leaky gut syndrome’. Findings here Green Lipped Mussel: GLMs are rich in glycosaminoglycans and glycosaminoglycan precursors, known as GAGs. An important GAG found in GLMs is chondroitin sulfate a well-documented structural ingredient for connective tissue found in the mucosal wall of the digestion. Findings here INFLAMMATION Green Lipped Mussel; the fatty acids in green lipped mussels with EPA (eicosapentaenoic acid) and DHA (docosahexanoic acid) are the most abundant. These are the important fatty acids that are known to reduce inflammation. GLM’s are natural COX inhibitors just like NSAIDS (non-steroidal anti-inflammatory drugs), so they can obtain the same pain free results without the negative side effects. They are also natural LOX inhibitors too. Findings here Devils Claw: is a flowering plant of the sesame family. Its root packs several active plant compounds and is used as an herbal supplement and its botanical name, Harpagophytum, means “hook plant” in Greek. Some studies suggest that compounds called iridoid glycosides, found in devils claw, may also have antioxidant effects. This means the plant may have the ability to ward off cell-damaging effects of unstable molecules called free radicals. Findings here Boswellia Serrata: shows suppression of inflammation and mechanism of action of extract might be linked to lipoxygenase and/or cycloxygenase. Providing maximum inhibitory response as compared to other fractions. The result strongly suggests that the oleo-gum-resin of B.S can be used efficiently as analgesic and anti-inflammatory agent. Findings here Curcumin: has proven to be beneficial in the prevention and treatment of a number of inflammatory diseases due to its anti-inflammatory activity. Arachidonic acid-derived lipid mediators that are intimately involved in inflammation are biosynthesised by pathways dependent on cyclooxygenase (COX) and lipoxygenase (LOX) enzymes. The role of LOX and COX isoforms, particularly COX-2, in the inflammation has been well established. Findings here MSM (Methylsulfonylmethane): is an organosulfur compound and often used for it’s anti-inflammatory and structural capabilities for joint health. In invivo, MSM reduced cytokine production involved in the inflammatory process. Ginger: contains anti-inflammatory compounds that function in the same way as COX-2 inhibitors and may help joint inflammation and namely OA (Osteo Arthritis). Findings here DEGRADATION Glucosamine HCL and
When we’re out walking our dog and they are panting, we rarely pay any attention, we know that it’s a typical behaviour associated with exercise. Equally, if it’s gotten a little warmer, we expect panting (within reason). But is there a time when panting can indicate something which does require some further attention? It’s a behaviour that we ask pet guardians about in a My Pet Nutritionist consult, so let’s get to the bottom of what panting is, and if it’s anything to worry about. What is panting? Panting is characterised by fast, shallow breaths, a wide-open mouth, and an extended tongue. It’s generally associated with a dog trying to cool down, also known as thermoregulation. Cooling results from the inhalation of cooler air and exhalation of heat along with the evaporation of water in the dog’s respiratory system. The respiratory system in dogs is made up of their mouth, nose, trachea and lungs and it serves two main functions. Firstly, like in humans, it is how the body exchanges carbon dioxide and oxygen. In general, healthy dogs will have a resting respiration rate of anywhere between 15 and 40 inhalations and exhalations a minute. The typical respiration rate when panting increases 10-fold, so up to 400 inhalations and exhalations per minute is expected. It’s second function is to regulate body temperature. A normal body temperature for a dog is between 38.3°C and 39.2°C. An increase by just 1-2°C can have major effects on the dog’s system. They therefore rely on panting as their primary means of expelling heat. There are three known patterns of panting: inhalation and exhalation through the nose, inhalation through the nose and exhalation through the mouth, inhalation through the nose and mouth and exhalation through the nose and mouth. It is suggested that the most effective cooling system is when air is directed through the nose and out through the mouth. So why don’t dogs sweat to cool down? The human mechanism for cooling down is to sweat. As sweat evaporates, we cool down. Due to the thick coats dogs have, sweat just wouldn’t evaporate resulting in a thick, furry coat full of sweat! Nice! Dogs do have sweat glands, but on their paws. It is rare to see a dog with sweaty paws after exercise. You will tend to find sweaty paws in response to stress – which is why you’ll see damp patches on the table at the vets or groomers. What are the triggers and causes for a dog panting? Exercise This is a well-known cause for panting in dogs. Exertion increases heart rate and overall body temperature. Therefore, to regulate their body temperature, dogs will pant. Heat It is suggested that it can take from 7-60 days for a dog to acclimatise to a temperature change in the environment. This can be influenced by body shape, size, coat type and length and the overall health of the dog. Some of the breeds that are more sensitive to an increase in environmental temperature include: Pugs, Lhasa Apso, Boston Terrier, English Bulldog, Boxer, Cavalier King Charles Spaniel and French Bulldog. These are known as brachycephalic breeds and due to their small nasal passages and short windpipes, they don’t pant as efficiently as other breeds. This puts them at a much higher risk of heatstroke. Dog Days of Summer Anxiety/Fear/Phobia Many dogs who suffer with anxiety or fear will pant. It is thought that the fear response increases the heart rate which in turn raises the body temperature. There are usually other signs that accompany panting in a fear response, such as yawning, pacing, crying, whining, shaking, lip licking or hiding. Storms and holidays with fireworks are often a source of anxiety for dogs, so it is quite common to see more panting during these times. There are many ways to help relieve anxiety in dogs including: Thunder Jackets, Plug-in diffusers – these release calming pheromones which mimic those of nursing dams when comforting their litter. Creating a safe place – a covered crate or a space under the stairs or a table. Top Tips for Anxiety in Cats and Dogs 6 Nutritional Tips for Anxiety in Dogs Panting accompanied with shaking is a typical stress response in dogs so consider whether there has been any change to their daily routine, even the smallest changes can be worrying for some dogs. Is panting a symptom of a long-term health condition? It can be. Heart failure When the heart is no longer pumping oxygenated blood efficiently, body parts and tissues will become oxygen deprived. The easiest way to correct this depletion is to increase respiration which often results in panting. Symptoms of heart failure include: Fatigue, Difficulty breathing, Loss of appetite, Weight loss, Coughing. Older dogs are more susceptible to heart issues. The ageing process naturally causes your dog’s organs and systems to deteriorate. Keeping Your Senior Dog Healthy Heart failure can also occur as a result of heartworm disease. Heartworms are spread through mosquitoes. Infective heartworm larvae migrate through the dog’s body until they reach the heart and blood vessels in the lungs. Symptoms of heartworm include: Coughing, Intolerance of exercise, Laboured breathing/panting. Natural Worming Options for Pets Obesity Overweight dogs will often pant excessively. This is due to the strain placed upon the cardiovascular system. In determining whether your dog is a healthy weight, you should be able to see a waistline, feel the ribs and from a bird’s eye view, your dog should have an hourglass outline. Maintaining a healthy weight in your dog should be achieved through species appropriate diet with portion control and regular exercise. Obesity in Pets Part I Obesity in Pets Part II Low Fat Fish Cushing’s Disease This is when the adrenal glands produce too much cortisol, also known as hyperadrenocorticism. Cortisol is produced and stored by the adrenal glands, two small glands which sit on top of the kidneys. Investigations of the cause will usually be tumours found on the pituitary or adrenal gland or
This is the stuff of most owner’s nightmare’s! Wriggly worms in the poop isn’t exactly heart warming, but fear not, we are going to take look at the different types of worms and how to naturally prevent them. A little 101 on all the worms and how to effectively and safely ward them off and manage potential problems. There are three main groups of worms to consider in our dogs, intestinal worms, these include, roundworm, whipworm, hookworm, tapeworm. Then we have lungworm and heartworm, although heartworm does not exist in the U.K. ROUNDWORMS Roundworms also know as toxocara canis are the most commonly found worms in our dogs. They have the appearance of spaghetti and can reach several inches long! They live in the intestinal tract of the dog and feed off undigested food. Roundworms are very common in puppies. Transmission Roundworms can be transmitted in several different ways. They can be passed from mother to puppy whilst in the womb and through the mothered milk when nursing. Roundworms can also be spread by sniffing or eating infected faeces or eating infected animals like rodents, birds and earthworms, that are of course infected. Symptoms Roundworms are the most serious for puppies and young dogs as they can suffer from malnutrition, weight loss and have pot dog pot bellied appearance, as well as vomiting and diarrhoea. You may also notice worms in your dogs poop or vomit. Diagnosis Faecal screen or visually identifying WHIPWORMS Whipworms also known as Trichuris vulpis, live in the caecum of a dog, this is a blind ended pocket located near the large intestine. They grow to around 30-50 mm in length and get their name from their whip like appearance with a thick anterior and a very long thin posterior. Whipworms attach themselves to the mucosal lining of the caecum and feed on blood and tissue fluids. Transmission Dogs become infected by consuming soil of faeces that is contaminated with whipworm eggs. Symptoms Whipworms cause serious irritation and inflammation of the lining of the caecum, causing watery, bloody diarrhoea, weigh loss, anaemia and lethargy. If infestation is large it can be fatal. Diagnosis Faecal screen HOOKWORMS Hookworms also know as ancylostoma caninum, get there name from their hook like mouth piece, they are around 3mm in size and very difficult to see with the naked eye. They hook themselves to the wall of intestines and ingest blood from the tiny vessels. Transmission Hookworms can be transmitted in several different ways, in utero, through mother’s milk, oral ingestion and the larva can burrow through the skin! Symptoms Hookworms can cause lots of symptoms including pale gums, bloody stools, poor growth, weakness and severe anaemia, that can lead to death. Hookworms can also cause dermatitis and itchy skin especially on the paws where the larva has buried into the skin. Diagnosis Faecal screen TAPEWORMS There are a lots of different species of tape worms, a common tapeworm is taenia echinococcus but the most commonly found species in U.K. dogs is dipylidium caninum, also known as the flea tapeworm. Tapeworms belong to the cestode family of parasitic worms, they are flat in shape. Tapeworms hook/suck onto the intestinal wall of the dog and absorb nutrients directly through their skin. Tapeworms are made up of segments, these are called proglottids that detach from the worm and are essentially a bag full of eggs, ready to infect the environment and their next host. Transmission Tapeworms are carried by live stock and your dog would need to ingest a cyst to be infected, the larva in that cyst would then grow into an adult tapeworm, if it is a flea tapeworm they must first ingest a flea that has been infected with tapeworm larva, that will develop into an adult tapeworm. Symptoms Tapeworms can cause a whole host of symptoms from dull coat, weight loss and vomiting. Dogs will often scoot and bite at their back end, and in some cases you will see a proglottide segment crawling around the anus. Diagnosis Faecal screen or seen proglottides in faeces. LUNGWORM Lungworm also known as French heartworm, Angiostrongylus Vasorum, live in the right ventricle of the heart and pulmonary arteries of our dogs. Transmission Lungworm is transmitted to our dog by either eating a slug or snail that is infected with lungworm larvae, the larvae can also be transmitted to our dogs through the slug/snails slime that is on dogs toys, water bowls or infected puddles. It be noted that not all snails and slugs are infected with lungworm. Symptoms Lungworms can cause serious damage if left untreated. There is lots of symptoms from vomiting, weight and appetite loss, pale gums, bruising and poor blood clotting. Coughing or coughing up blood, as well as other breathing problems such as emphysema and pneumonia. Lungworm also cause heart problems and in extreme cases heart failure, as well as seizures. Diagnosis Faecal screen HEARTWORM Heartworm or dirofilaria immittis is a parasitic roundworm that is a species of filarial worm, that live in the pulmonary arterial systems and heart. They can grow up to several inches long. Transmission Heartworm is transmitted by a mosquito that is infected with microfilariae, an early stage heartworm larvae. The mosquito bites the dog releasing the microfilariae into the blood stream where they make their way to the pulmonary arteries and heart, to develop into adult heartworm. Symptoms Symptoms can be anything from, fatigue, poor appetite, weight loss and coughing to chronic cardiovascular and respiratory disease. In serious cases dog can collapse due to caval syndrome, this is when blood is blocked getting back to the heart due to a high worm burden. Diagnosis Blood test for macrofilariae, these will not be present in blood till after 6 month of initial infection. Antigen test, this tests for a specific protein released by female heartworms, The earliest you can test for this protein is 5 months after initial infection. It is advised to have an annual testing for heartworm. Natural Prevention
Whilst we don’t like to bash pet foods and understand that people are often looking for convenience and economical options, we always feel it’s important to highlight why dry food is not a good option for your pet. Fresher food always prevails in my clinic and there are thousands of people who will testify to the wonderful effects of a fresh food diet. There’s a myth that feeding fresher foods is a lot more expensive. Like anything, there is something to suit all budgets and well we believe, if you have invested your time and love into a furry member of the family, then it’s worth considering the best options to support their health. Before we begin to look at dry foods, its important to understand a little more about our dogs and where they have come from to understand their needs. We have domesticated dogs for around 30,000 years. Dogs are facultative carnivores which means their main diet should be a meat based diet but they can survive on other foods if required. Cat’s are obligate carnivores, meaning they are solely carnivorous and wouldn’t survive without a meat based diet. Dogs are a species of canid but domesticated dogs are the closest related ancestors to the grey wolf. We have changed the shape and size of domestic dogs but there has been very little evolutionary change to the digestive system. A domestic dog’s digestive system is designed to eat fresh raw meat and bones (this is where their high and relative need for calcium and phosphorus come from). The first dry food was only produced in 1957 by Purina and since the 1970s, the average age of a dog has gone from 17yrs to 11yrs. Nutrition is not solely responsible for this drop but feeding ultra processed foods, plays a huge huge part in your dog’s longevity and quality of life. Dry food Is made by the extrusion process, extruded food goes through four extremely high heat processes, so you can imagine what that does to the nutrients. You are left with something that is dead “food” void of nutrients, antioxidants, enzymes, fatty acids and probiotics. The food is then sprayed with a layer of fat and flavour enhancers to make it palatable to dogs, then sprayed with a pre mix of synthetic vitamins and minerals. As if all this is not bad enough, food that contains protein and carbohydrates when heated to high temperatures, causes glycemic end products to be formed. AGE’s have been linked to free radical damage, cancer and premature ageing. The other big issue with pet food is the amount of glyphosates, a chemical herbicide (weed killer) used on crops such as wheat, corn, soy and potatoes, commonly used on ingredients found in pet foods. When certain brands were tested for glyphosates, the amounts were considerably higher than expected. Glyphosates are deemed carcinogenic and linked to cancer and many other diseases. We know one in two dogs will get cancer in his/her life time. Research here Another concern with dry food, is most contain a huge amount of carbohydrates. As we know, our dogs are facultative carnivores and our cats, obligate carnivores, which means they need a meat based diet to thrive. Both cats and dogs have no to little nutritional requirements for dietary carbohydrates. They can obtain everything they require from a diet that contains only protein and fat. Energy metabolism in both cat and dog can be based on fat oxidation and the breakdown of protein to produce glucose. Carbohydrates=sugar and can cause a host of problems including systemic inflammation. If your cat or dog has IBS, IBD, arthritis, allergies, bad breath, constant ear infections, urinary issues, obesity, yeast infections, kidney disease, liver disease, thyroid issues, cancer and more, then the first thing to do is look to the food you are feeding, and go from there. Structurally, carbohydrates (starches mostly) are essential to dry pet food manufacturing as commercial extruded pet foods use these starches to give the food structure and texture. Even some canned dog foods contain a carbohydrate source to create a gelling agent. Frequently used carbohydrate sources used in dry food/pet food include grains such as rice, maize, corn, potatoes, legumes, and fillers such as milled beet. The carbohydrate content is not given in dry food but you can work it rather easily. Some popular fed dry foods have shocking results! In most cases there’s more carbohydrates in the food than protein! Most of these dry foods are almost half a bag of carbohydrates. If you want to work out the amount of carbohydrates in your dogs food add the percent of: Protein Fat Ash Fibre Moisture (if not stated 8%) together then subtract the amount from 100, this will leave you the percent of carbohydrates in the food. Here are some of the most common dry food brands: JAMES WELLBELOVED protein 20% Carbohydrates 48% JAMES WELLBELOVED GRAIN FREE protein 21% Carbohydrates 46.8% MILLIES WOLFHEART LAMB AND VEG Protein 19% Carbohydrates 45.5% EDEN protein 45% Carbohydrates 18.5% WAINWRIGHT GRAIN FREE protein 25% Carbohydrates 40% AVA MEDIUM ADULT protein 26% Carbohydrates 46.6% HARRINTONS GRAIN FREE protein 25% Carbohydrates 44.5% BURNS protein 18.5% Carbohydrates 57.8% ROYAL CANIN protein 25% Carbohydrates 45% CANAGAN protein 33% carbohydrates 32.5% TAILS protein 22.3% Carbohydrates 46.9% AKELA Protein 39% Carbohydrates 20.5% ORIJEN protein 38% Carbohydrates 23% HILLS IDEAL BALANCE protein 23.5 Carbohydrates 44.1% AATU protein 32% Carbohydrates 43% BARKING HEADS protein 26% EDGAR AND COOPER Protein 25% carbohydrates 41% STEP UP TO NATURALS protein 22% Carbohydrates 47.2% BAKERS protein 21% Carbohydrates 50% WAGG Protein 21% Carbohydrates 49.8 PEDIGREE protein 21% Carbohydrates 42.9 The Ideal Omega-6 to Omega-3 ratio for pet food is 4:1. This can go up to 6:1 quite comfortably but reaching a higher ratio than this can cause a huge amount of systemic inflammation. The average dry food offers 20:1 and can go as high as 50:1. This is another blog to venture. A required percentage of moisture in your pet’s food should
I see many sick cats and dogs (mostly dogs) coming through the door at MPN, with owners at a loss as to what to do next. Whilst we see so much disease and every pet is different, there are some set things I always recommend to everyone, that are imperative to your pet’s health. This is to detox their life and GET RID OF THE CHEMICALS. I have heard several sad stories about reactions and disease caused by treatments, mostly neurological damage and death from flea treatments and worming stories where the dog went into fits and endured life long seizures. If we aren’t personally meant to handle these chemicals, then they shouldn’t be going on or in our pet’s bodies. Conventional chemical flea and tick treatments from your vet or over the counter, are highly toxic pesticides that accumulate in the blood, skin and tissue. When you give your dog these chemical treatments, they work systemically (throughout the body). They are absorbed into his/her blood so when a flea or tick feeds on your dog’s blood, they also eat the chemical Isoxazolines, and become paralysed, eventually dying. Both fleas and ticks have to bite and latch on, to suck your dogs blood, before becoming paralysed and dying from the pesticides. It can take hours upon hours before the fleas and ticks die. This allows sufficient time for the fleas to become bothersome and the ticks to spread disease. The problem with these chemicals is to kill the parasites, they have to poison your cat or dog first. These awful chemical treatments can also cause neurological issues and permanent damage in cats and dogs. The US Food and Drug Administration (FDA) put out a warning on Isoxazoline flea and tick products in September 2018, warning on the potential neurological adverse reactions. The side effects range from, diarrhoea, vomiting, lethargy, seizures, convulsions, skin disorders, ataxia and death. Although this warning has been given, sadly the FDA still states that they work with manufacturers and deem it safe with side effects now listed to make this a known danger? Apparently to note dangers within the labelling and making statements on potential dangers, now makes this a non safety issue. I’m still scratching my head. Any safety data on these products are only tested a few months, so we don’t even know about the long term implications. Those treatments containing Isoxazoline: Bravecto (fluralaner) tablets for dogs Bravecto (fluralaner) topical solution for cats and dogs Credelio (lotilaner) tablets for dogs Nexgard (afoxalaner) tablets for dogs Simparica (sarolaner) tablets for dogs Revolution Plus (selamectin and sarolaner topical solution) for cats and used in the prevention of heartworms Natural Solutions Using a natural preventative is far safer and effective than conventional means. In using chemical treatments, these are designed to kill the parasite once on the host, whereas the natural prevention aims to repel fleas and ticks, so your cat or dog doesn’t even become a host. This is a more effective approach at preventing disease if done appropriately. To protect against fleas, ticks and worms, there are several natural and effective options you can consider so please read on. Flea, tick and worming products Flea products and tick products are incredibly toxic and overload the body when the immune system is already under challenge. Fleas aren’t a great concern although very bothersome and cause discomfort and allergies in your pet, but ticks are a problem. Make sure after every walk you check your dog thoroughly and invest in a tick removal kit if you are in a zone for ticks (there’s a tick key listed down below). They can be dangerous to your dog as they carry disease. There are lots of natural products out there. Rotating them is important as fleas and ticks are adaptable and you need to make sure your pets are not a desirable host. Homemade Itchy Dog Spray of apple cider vinegar mixed spritz potion can be an effective flea and tick deterrent; 1. 250mls of organic Apple cidar vinegar and preferably from the mother (this means Apple cider vinegar that is simply unrefined, unpasteurised. unfiltered and from the mother). Organic AC Vinegar 2. 250mls of distilled water, filtered water, bottled water but definitely not tap water. 3. Fresh chamomile (organic preferably) or a teabag steeped in boiling water for 30 minutes (to be added as part of the 250mls water). 4. 10 drops of Organic lavender aromatherapy oil and/or a few drops of essential oils such as lemon eucalyptus, tea tree, sandalwood, clary sage and patchouli. If you decide to use this on the cat too (avoid the aromatherapy oils due to the phenolics: this can be toxic to cats). 5. Water spray bottle. I prefer brown glass but we don’t have to go fancy here. Just make sure its stored in a cool dry place and if plastic, doesn’t sweat as PCB’s could leak into your lovely potion. Alternatively, you can go for a spray already made up from Greens for healthy pets called Don’t Bug Me! Don’t Bug Me Hedge row hounds offers a wonderful herbal mix called natures bounty, that is easily and safely added to food. Natures Bounty Diatomaceous earth is a good effective option although if your dog has sensitivities, allergies or any breathing problems, tread with caution. Food grade diatomaceous earth is made from teeny, tiny sea creatures, often found in places like the white cliffs of Dover. It dehydrates and suffocates the parasites and their eggs, thus killing them. Please ensure this is a good quality, food grade product as it can have high levels of toxicity. It can be used to sprinkle around the home and dusted through your dog’s coat. Care should be taken not to breath in the powder (caution with your dog too). Diatomaceous Earth Another lovely spray with beautiful essentials, sprayed before you go on a walk and perhaps afterwards, can be helpful in warding off critters. Biospotix do natural spot ons and collars. Biospotix Flea Spray A natural flea collar or
A brilliant guide on how to vaccinate safely, here it is in all it’s glory, everything you need to know about taking care of your pet, not over vaccinating, being responsible and taking care of your pet, based on scientific review. Guidelines from the World Small Animal Veterinary Association are at the core of this article and something many vets ignore or don’t know about. UNDERSTANDING VACCINATIONS, IMMUNISATION, TITER TESTING AND WSAVA GUIDELINES The World Small Animal Veterinary Association (WSAVA) is a global veterinary community that bases their guidelines on evidence based veterinarian medicine. These guidelines are to give vets the current scientific advice on the best vaccination concept. In this blog we will be discussing core vaccinations, the difference between vaccinating and immunising and WSAVA guidelines on vaccination protocol and titer testing. Core vaccinations are “parvovirus, hepatitis and distemper” this is the DHP three in one vaccination currently in the UK. The only vaccinations you can give on its own is parvovirus. What is the difference between vaccinating and immunisation? Just because you have vaccinated your dog does not mean that your dog is immunised, when we give a vaccination, we aim to immunise. When a dog is immunised it means that the vaccination has worked and the dog has immunity to the diseases it has been vaccinated against. If you give the last vaccination when your pup is too young, they will still be covered by the mothers maternal immunity and the vaccination will not work/take. Then once the mothers maternal immunity has wained they can be unprotected against those diseases. If you have a dog that is a non responder, it is impossible to immunise them no matter how often you give a vaccination, these dogs will always be susceptible to those diseases. WSAVA guidelines on puppy vaccinations The recommendations are for initial core vaccinations at 6-8wks of age, then every 2/4wks until 16wks of age, then a booster at 6-12 months or a titer test 4wks after the 16wk vaccination, to check if the puppy is immunised. If the pup is immunised, then the guidelines say there is no need for the 6-12 month booster. The difficulty is knowing at what age it is best to give the first vaccination as most pups with be covered by their mothers maternal immunity (MDA). Maternal immunity is passed to the pup through the colostrum in the mother’s milk. Maternal immunity can begin to wain as little as 8 weeks but can last up to 14-16 weeks and for this reason, the WSAVA states, there is “No single primary vaccination policy will therefore cover all situations”. When getting a pup, it is important to know if the mother is immunised, if so the pup will have some maternal immunity. If you vaccinate early and give three vaccinations, you risk over vaccinating your pup but if you wait till later to vaccinate, there is a risk of your pup getting one of the illnesses. It depends on your pups circumstances and what risk you see as the greater. My advice is to base your decision on this. If the pup is hand reared, the pup will not have any maternal immunity therefore the earlier vaccinations would be more beneficial. Waiting to give the last vaccination at 16 weeks is important as this is when the dog is most capable of responding to the vaccination, as all of the mother’s maternal immunity will have wained. How often should core vaccinations “parvovirus, hepatitis and distemper” be given? Often these vaccinations are given annually, this should not happen as the data sheet that comes with the DHP vaccine states “once every three years”. Once every three years, is in most cases, still too frequent for most dogs as the science has proven by serological testing and by challenge that core vaccinations can last up-to the life time of the pet. This is why it is so important to always titer test before giving core vaccinations. WSAVA guidelines state not to be given more frequently than every three years. This does not mean to give every three years, it means they should not ever be given sooner that three years. Please see WSAVA guidelines below. WSAVA GUILDLINES ❗️VACCINATIONS SHOULD NOT BE GIVEN NEEDLESSLY❗️ ❗️CORE VACCINATIONS SHOULD NOT BE GIVEN MORE FREQUENTLY THAN ONCE EVERY THREE YEARS BECAUSE THE DURATION OF IMMUNITY IS MANY YEARS AND MAY BE UP TO THE LIFE TIME OF THE PET❗️ ❗️A DOG THAT HAS RESPONDED TO CORE VACCINATIONS MAINTAINS SOLID IMMUNITY (immunological memory) FOR MANY YEARS IN THE ABSENCE OFANY REPEAT VACCINATIONS❗️ ❗️IT MUST BE REMEMBERED THAT EVEN THE THREE YEAR LICENCE IS A MINIMUM DURATION OF IMMUNITY AND FOR MOST CORE VACCINATIONS THE TRUE DURATION OF IMMUNITY IS LIKELY TO BE CONSIDERABLY LONGER IF NOT LIFELONG❗️ ❗️AN ADOPED ADULT DOG (OR PUPPY OVER 16WKS OF AGE) OF UNKNOWN VACCINATION HISTORY REQUIRES ONLY A SINGLE DOSE OF CORE VACCINATION TO ENGENDER A PROTECTIVE IMMUNE RESPONSE❗️ WSVSA statement on giving more than one core vaccination to an adult dog (or pup over 16 weeks of age and restarting vaccinations is….. ❗️THIS PRACTICE IS UNJUSTIFIED AND IS SIMPLY CONTRARY TO THE FUNDAMENTAL PRINCIPLE OF IMMUNOLOGICAL MEMORY❗️ How does a titer work? To explain titer testing a little more, a titer test is a simple blood test that will look for circulating antibodies in the dogs bloodstream. When you do a titer test, the level of the titer (antibodies) is irrelevant, it doesn’t matter if your dogs titers come back high or low. Any measurable antibodies means the dog has immunity. These titers will go up and down depending what the circumstance is. A high titer doesn’t mean your dog is more immune than a low titer, a high titer can mean one of two things. The dogs immune system has been over stimulated by vaccinations or your dog has just come into contact with a said disease. For example, if there is a parvo outbreak in your area, your dogs
There’s some mixed feelings about mushrooms but they get a lot of press and rightly so. They are wonderful and each have a magical affect with direct correlation and clinical research to immune and organ support. There are a lots of species of mushrooms and not all medicinal but most magical. Mushrooms help to regenerate, prevent, protect and intervene with certain disease states and the research is growing. The magical mushrooms we will look at today are Maitake, Shiitake, Reishi, Cordyceps, Coriolus and AHCC (active hexose correlated compound). These mushrooms offer nutritional abundance and amazing cell and immune function: Minerals such as potassium, selenium, sodium,zinc, phosphorus Sugars such as mannitol, xylose, glucose, galactose, mannose Vitamins such as b complex, folic acid, vitamin D Proteins essential amino acids Lipids such as phospholipids, sterols, free fatty acids, mono-, di- and triglycerides Polysaccharides such as glycogen and beta-D-glucans Enzymes such as proteolytic The most powerful of all of these are the polysaccharide fraction, mainly beta-glucans, responsible for the immune-modulating effects. Fungal beta-glucans have been shown to activate leukocytes, which depend on structural characteristics of beta-glucans. Findings here Polysaccharopeptides are protein-bound polysaccharides (carbohydrates) that are found in many mushrooms. Krestin (PSK) and Polysaccharide Peptide (PSP) are two types of polysaccharopeptides. Both PSK and PSP possess powerful immune-boosting properties. They promote immune response by both activating and inhibiting specific types of immune cells and by suppressing inflammation. Due to their ability to naturally strengthen the immune system, PSP and PSK are commonly used as anti-cancer agents in conjunction with human surgery, chemotherapy and/or radiation in countries like Japan. Maitake (Grifola frondosa); may help to regulate blood sugar, support heart health, boost the immune system, particularly in cancer care. In fact maitake has shown the most promise in helping support cancer patients. In 2004, an in vitro study showed the effectiveness in 3 types of dog cancer, CF33- Mammary cancer cells, CF21-Connective tissue cancer cells and CL1- Lymphoma cancer cells. The significant study showed that the D-fraction of maitake held the ability to inhibit the growth of the CF21 and CF33 cancer cells. Findings here Shiitake (Lentinula edodes); contain ergothioniene, an active compound that provides potent antioxidant, anti-inflammatory and regenerative properties, as well as lentinan, a compound that may help fight against bacterial, viral and parasitic infections. Shiitake is shown to support liver function, lower blood cholesterol levels, help regulate blood sugars, support skin conditions, used in supporting the immune system in prostate or breast cancer. Findings here Reishi (Ganoderma lucidum): a powerful medicinal mushroom that has been found to possess immune-modulating and immune-potentiating capabilities. Reishi has been characterised as a wonder herb, helping with possible inflammation and allergic reaction. Reishi may help with liver function, fatigue, cancer, skin disorders, digestive issues and possible leaky gut. Findings here Cordyceps Sinensis; may help endurance and stamina during exercise, may have anti-ageing properties due to it containing an enzyme called super oxide dismutase. May have a potential anti-tumor effect, may help to modulate blood sugars, support heart health and help to fight inflammation. Findings here Turkey Tail (Coriolus versicolor); contains a variety of powerful antioxidants and other compounds that may help boost your dog’s immune system and even help fight certain cancers. possessing powerful immune-boosting properties. They promote immune response by both activating and inhibiting specific types of immune cells and by suppressing inflammation. A test-tube study found that turkey tail extract modified gut bacteria composition by increasing populations of beneficial bacteria such as Bifidobacterium and Lactobacillus whilst reducing potentially harmful bacteria such as Clostridium and Staphylococcus. Findings here AHCC® (active hexose correlated compound); is a natural substance extracted from certain species of basidiomycetes, a class of mushrooms that includes shiitake. Research on a canine study showed AHCC treatment might be effective for improvement of clinical state and anti-tumor effect. Findings here Findings here Mushrooms are a wonderful addition and one to explore if you wish to add them to your pet’s plate. As always, we are here to help, so check out our services, click the link below. Consultations MPN Team x
