Cancer in Pets Part 1: Immunity and Diet

Cancer is the second most common reason clients consult with MPN. Cancer is an epidemic! It’s estimated that almost 50% of cats and dogs will die from some form of cancer. When considering the full picture of health, at MPN we look at genetics, breeding, health of pregnancy, birthing, weening, environment, nutrition and the functionality of all 8 body systems (neurological, digestive, cardiovascular etc). In order to truly understand your pet’s needs, all these factors must be taken into consideration to obtain the best plan. Particular breeds or certain breeding will transcript coding that makes cancer more likely in certain cats and dogs, however this isn’t exclusive to genes and breeding. This is prevalent and likely in pets who experience chronic inflammation and experience an immune malfunction due to a number of factors. What is cancer Cancer is the uncontrolled growth of abnormal cells in the body. Cancer develops when the body’s normal control mechanisms cease to work. Old cells do not die and form new, abnormal cells that can grow at a fast rate. These extra cells may form amass of tissue, called a tumour. The Immune system In 2013, Dr Thomas Seyfried demonstrated that cancer is a metabolic dysfunction of the mitochondria (energy producing organelles in cells), triggered by toxin overload. That is the very nature of cancer but how we end up there is very much to do with the immune system. In order to support cancer one of the major contributing factors is the immune systems functionality and how it responds to invading cancer cells. Cancer is an inflammatory disease. I see Cancer as an ‘immune malfunction’ where a consistent imbalance in the immune system, tips into inflammation. In more than basic terms, the immune system is split into 2 phases, Th1 and Th2. In a healthy pet, Th1 and Th2 cells are maintained in a carefully regulated balance. If a bacterium enters the body, it activates Th2 cells that dominate the network to begin a cascade of immune events leading to an antibody response that clears the infection. If a virus enters cells in the body, it activates Th1 cells which dominate and instruct the killer cell response to clear infected cells. Once the infection is cleared, suppressor cells are activated to shut down the dominate response and bring the network back into a resting state. If the suppressor cells do not act to bring the network back to a resting state, a pathological Th1 or Th2 dominated immune system results. A Th2-dominated immune system is characteristic of cancer patients where the killer cell response in TH1 is suppressed (recognising defective cells). Patients with advanced cancer often have impaired cell-mediated immunity associated with a switch from Th1 to Th2. Research shows that cancer patients, exist in a state of Th2-mediated “chronic inflammation”. Findings suggest that Th2 dominance status encourages carcinogenesis (the initiation of cancer formation). There’s a lot we know about immunity but still so much we don’t. It’s a complex issue but understanding the very basics can help us look at things differently and can help to support your pet. Cancer diet Nutrition is obviously a key factor in supporting cancer. We find the fresher the food the better. Natural, fresh, homemade, and perhaps raw are best (it depends on the immune function: I often suggest lightly cooked dependent on the individual). Intense processed food is definitely not the best choice for optimum health. We know dry food can lead to more inflammation from independent research. Most dry food contains around 35-50% sugars, due to the starch content that binds it all together. Cancer LOVES sugar, this was documented years ago but has never been much of a focus with regards to cancer care until more recent years. We also know from recent research from Dog Risk at the University of Helsinki, that a controlled study of dry fed and raw fed dogs, raised disease markers when fed dry food. The study demonstrated clear data of increased plasma homocysteine in the variations of the dry fed dogs as opposed to raw. We know that homocysteine is a marker for disease and closely linked to cardiovascular complications and other disease states. Recent advances have shown that increased plasma homocysteine could be correlated to cancer also. We are not necessarily advocating raw, in fact in some cases we actively recommend lightly cooked but the above demonstrates differences in metabolites, in dry verses fresh. Fresh always seems to prevail with the best results. It is important to know that not all foods will suit your pet and looking into this is an imperative part of the process. Immune mediated responses can arise from food sensitivities, food allergens, environmental allergens and toxins on a daily basis and sometimes owners aren’t aware of this. This can lead to a permanent state of inflammation. An allergic response is a TH2 response so consistently being exposed to allergens can put your pet in a permanent state of TH2. See above to know that this isn’t groovy for cancer patients or general well-being. Allergies and cancer can by hyperlinked. In fact, histamine (a compound often released in response to an allergy) is commonly known to induce tumour proliferation and immune suppression in certain cases. Ketogenic Diet The ancient Greek practitioners were well known for using ketogenic diets and although it seems more of a new concept and revelation, it’s been around for donkey’s years, so we can’t lay claim to creation. That said, there is a lot of information and research regarding the benefits of keto diets and cancer amongst other disease. In fact, there’s thousands of research papers, many based on animals. There is even a wonderful centre in America called Keto Pets Sanctuary who specialise in keto research. A ketogenic diet is based on moderate protein, high fat and very low carbohydrate. The ratio usually required to induce ketones is fat to protein 2:1. That is a very high fat diet and should be fed with caution. If a diet provides a high fat content, glycogen
Kidney Disease and Natural Nutrition for your Pet

Alison’s mother had chronic kidney disease (CKD) and from having a 2-year prognosis based on a bad heart condition, we wanted to get her off dialysis and extend her life expectancy. Alison was a clinical nutritionist at the time (for humans), with a focus on functional medicine and so made it her mission to get her in a better state of health and mind. This condition was never going away but life could be easier for her. After much research and countless testing, we discontinued dialysis, created an impeccable diet and added in a supplement regime. Her mother continued on to have another 8 years with pretty much problem free health (other than the obvious). Ever since then, Alison has seen a lot of cats and dogs with the same problem. Although their nutritional requirements are different to humans, the general rules and pathophysiology’s apply. It’s all a balancing act at maintaining health that can be finely tuned to help with wellness. We are not ‘kidney-ing around’, so read on! Kidney disease – chronic and acute If your pet is presenting with kidney disease, it’s either acute or chronic. Acute Kidney disease presents suddenly and is more easily reversed. Acute is usually due to an obstruction or ingesting a toxic substance or some such case. Prognosis is always better than chronic. Chronic Kidney Disease (CKD) can take months or even years to identify itself. In fact, most pets don’t even show symptoms until 70-75% of kidney function has been lost! Signs and symptoms of CKD There are number of signs and symptoms in CKD. If any of these arise consistently, you should go to the vets and get it checked out. I would say the first signs would be excessive thirst and weight loss but this is an extensive list: Ascites (swelling of the abdomen) Blood in urine Diarrhea Decreased urination Urinating outside of the litter tray Frothy urine Increased water consumption and increased urination Lack of appetite and weight loss Lethargy Pale gums as a result of anaemia Ulcers on the tongue, inside cheek or gums Joint swelling in conjunction with some of the above Muscle wastage (this tends to appear when advanced) Seizures Blindness Vomiting Weight loss Unfortunately, the majority of these aren’t necessarily specific to CKD as signs and symptoms can vary from case to case. A visit to the vets as soon as any symptoms arise is always the best option. Kidney Function Kidneys have a lot to do and help filter the blood by getting rid of waste products such as glucose, salts, urea, uric acid and unwanted water. The waste products and additional water become urine, which eventually gets eliminated when your pet urinates. The filtering of waste is done by a network of tiny nephrons, as blood passes from the capillaries through the nephrons, essential molecules are kept, but waste products are removed and expelled as urine. The kidneys help regulate the amount of water they retain in our blood and their bodily potassium and sodium levels. The kidneys also produce three major hormones that help regulation of other mechanisms. Calcitriol is a form of vitamin D that helps calcium absorption, Erythropoietin encourages bone marrow to produce red blood cells and renin helps to regulate blood pressure. Diet for CKD The checklist for CKD A fresh and unadulterated fresh food diet Low in Phosphorus (0.2% – 1% dry matter) Moderate in protein Omega fats and antioxidants Low in salt (added salt in particular) Super tasty and easily delivered(hunger can decrease in CKD) Regulated treats that are part of the daily calorie intake No leftovers fed off the plate The use of an appropriately formulated diet is the only treatment that has been shown to prolong survival times and improve quality of life in pets with CKD. We have seen the best results with freshly fed pets on a specific formulated diet whether it be home cooked or raw. Cooking tends to reduce phosphorus levels and is often preferred over raw food. Dry food is a big ‘no no’ in CKD. Dry foods are dehydrating to the bowel, this delivery system can increase thirst and tax the kidneys further. Fresher and more bioavailable proteins are more effective as the kidney’s don’t have to work quite so hard. The protein in dry food can be cross-linked and not very easily assimilated. Dry foods are often higher in sodium and contain a large content of starch, both inappropriate for cats and dogs and kidney disease. Restricting dietary protein is controversial as testing and research was mostly based on processed food fed cats and dogs with limited solid findings. There isn’t a clear consensus as to what level protein intake should be reduced to in the diet of pets with CKD. In stage 1 and 2 CKD, we find moderate levels of fresh and more bioavailable proteins, low in phosphorus and reduced sodium and potassium is the best. We always work with blood tests to see the markers of poor function such as urea and other nitrogenous substances and get a professional to formulate for you. The type of protein you feed a dog with CKD should also be considered. Protein with high biological values leaves less waste behind. For this reason, protein derived from sources such eggs, fish and meats are preferable to vegetable-derived protein such as tofu. In pets with CKD, the excretion of phosphorous is impaired, which can result in further damage to the kidneys. Therefore, while an important component of a healthy pet’s diet, phosphorous should be restricted somewhat. In fact, dietary restriction of phosphorous has been shown to slow down the progression of CKD and this has been key to my practice in pet nutrition. Foods highest in phosphorus include raw bones, dairy products, organ meats, and egg yolks. That does not mean not to feed these foods at all, as they are an important component of a healthy diet, but they should be fed in moderation. When it comes to sodium, there are
What is the best food to feed my cat or dog?

Oh my goodness this is an exceptional question and one food does not fit all. However there are lots of things to consider and hopefully we will be able to point you in the right direction. First a little about some basics to get you searching. In short we find the fresher the food the better. We are not a fan of the highly processed foods that you mostly find on the supermarket and veterinary shelves! Rule of thumb is, if you don’t recognise the ingredient on the pack, don’t buy it! If you are feeding dry food, no matter how good the ingredients are, we strongly suggest you ditch the bag and look for an alternative, if you can afford to. Even if it is grain free it contains a lot of starch to help the composition and structure of the dry food. Starch equals sugar and as we know sugar is bad for us, and our pets’ do not have a high requirement for carbohydrates in their diet. Deceptively some of the dry food can contain almost 40-50% carbohydrates and the worst thing is, it doesn’t have to be stated on the pack. So there you are, feeding your grain free superfood blend thinking you are ‘rocking it’ only to find you are non-the wiser to it’s awful health implications. Yes your cat or dog might seem ok now but what about in the future.. nutrition is investment in your health right? So it’s incredibly important what you feed to your pet as to what they may suffer later down the line. Part of the reason of wanting to consult in a different way and try and prevent issues is because we see many, many sick pets coming through our doors and we don’t always think it’s necessary. There’s plenty that comes into play with our health and our pets. Genetics has a huge part to play but these genetics are majorly influenced with how we and our pets interface with the world. This includes nutrition, the environment, vaccinations, flea and worm treatments, physiological stress and so on. But if you get the baseline of nutrition right, then you are giving your pet a better chance at good health. With consistent toxins and technology exposure we need to consider supporting detoxification too. My specialty is how nutrition can interplay with genetics,switching genes on and off. Using diet and supplements to help ward off issues but also to help manage them when they have arisen. So far so good? Here are some of the foods we recommend. This is very broad and dependent on each pet but as a rule of thumb, we like these types of foods and the brands mentioned as a starting point. Raw food/BARF We started off as an avid die hard raw foodies! As time has gone on, we realised that this doesn’t suit all and to promote this being done at home, even well, is a risk as food alone does not give your pet everything he or she requires. That doesn’t excuse us from the raw food gathering and revolution. We often suggest raw as a commercial food, from a reputable company who do it well. There are no nutritional shortfalls and an overall balance is offered. We might upset some raw foodies here but on average even those cats and dogs who come to me home raw food and ‘well considered’, a good 50% of them have nutritional deficiencies. Home cooked food This is a wonderful alternative to raw feeding. It’s fresh and lightly cooked and we offer recipes to follow if you wish to DIY. We love home cooked meals delivered to the door also. You can get this for your pet too. Raw and dehydrated food This is a great solution if you don’t have a freezer or much freezer space, going on holiday or even keep something in the cupboard as a back up. This is often raw or lightly cooked, fresh food that has been air dried, dehydrated or freeze dried. All processes are slightly different and freeze dried is the least processed but the most expensive. Canned and Dry food We avoid dry food and canned food if possible. Often canned food is irradiated whilst in the aluminium tin. This is rather dangerous longterm and offers dead nutrition! If you are going to buy tinned food I urge you to ask the company how they process at the final stages. Our Ultimate Raw Feeding Guide and Ultimate Puppy Guide provide balanced recipes raw and a list of brands we recommend. MPN Team x
5 reasons why your dog eats grass

Many dog owners ask My Pet Nutritionist, why their dog is eating grass. The truth is, eating things that are not deemed a food, is rather common among dogs and often not a concern and referred to as pica. However, there are certain health related reasons why pets can be prone to eating grass. It’s known as an emetic and helps to purge and rid the body of unwanted substances such as foods. Here are some reasons why your dog may be dining out on grass! Grass is an emetic Most of you may be well aware that dogs will sometimes eat large amounts of grass in an attempt to make themselves throw up. After they consume a large amount of grass, they’ll often display some nauseous behaviour and then they’ll vomit. It’s completely normal for your dog to vomit occasionally but if this is a general occurrence then this must be looked into. Dogs are intuitive and selective and know what’s for them best in terms of intentionally ridding their system of something that could be toxic, or making them poorly. In short, a dog may be eating grass due to illness or eating something unsuitable. Dogs may eat grass to fulfil a nutritional requirement. This could be to enrich their diet with fibre. On a natural and raw diet, vegetation can add so much fibre, prebiotic and nutritional diversity. This is essential for a good functioning gut and nutritional status. We know that grass contains an abundant source of fibre and since grass is a living green food it contains phytonutrients. It’s high in potassium and also contains chlorophyll that helps aid in cleansing the body. It could be a way of easing nausea, gas or digestive issues and disease. Grass has soothing properties that can aid digestive comfort. If you suspect it could be digestive issues and grass eating is also accompanied by other symptoms such as diarrhoea or constipation then get this checked out. I always consider a natural enriched diet that is appropriate for dogs. They may be suffering from parasites such as intestinal worms. Plant material may increase intestinal motility and help to eliminate intestinal parasites. Being an emetic this may help expulsion of unwanted parasites via vomiting also. Its instinctive and enjoyable. Some dogs consider this pastime fun and may eat grass to occupy themselves. Please note vomiting grass and food on a weekly basis is not within the normal remit. Always consider the quality of the food your feeding and mental stimulation you are providing your dog. To ensure a happy and healthy dog my recommendation is always to look at natural, home cooking (researched and balanced), raw diets and better commercial home style diets, raw diets and raw dehydrated. Probiotics and prebiotics help repopulate and fortify the beneficial bacteria in your dog’s gut, while digestive enzymes provide what the entrails or the guts of their prey species would provide. These enzymes provide a rich source of amylase, lipase and protease, which can help your pets process food much more successfully. Chlorophyll in liquid form can help reduce grass eating and provide a slight detoxifying effect that your dog may require. It is full of trace vitamins and minerals and very much mimics the nutrition offered from grass. Wheatgrass is also a wonderful thing to grow in your garden or apartment, for your dog to graze on and obtain the pleasure and benefit from a nibble here and there. We hope you found this beneficial. MPN Team x