Here at My Pet Nutritionist, we see a lot of worried puppy parents, struggling with pyoderma. Skin conditions are a very common topic at MPN HQ, so let’s take a dive into pyoderma, what it is, what causes it, and how to support the body with it. What is Pyoderma? The word pyoderma, literally translates to ‘pus in the skin’ (‘pyo’ = pus, ‘derma’ = skin). The condition presents as acne-like spots on the skin, often in the chin area, and around the lips. Pyoderma is a bacterial skin infection, the most common bacteria affecting it being Staphyloccocus intermedius. When there is too much of a specific bacteria present on the skin, the risk of pyoderma is significant. Pyoderma can happen at any age, but is particularly common in puppies – known as puppy pyoderma. Pyoderma can spread between humans and dogs, so it’s important to clean your hands thoroughly when you touch the affected areas on your dog. Findings Here Findings Here Causes of Pyoderma A common contributing factor of pyoderma is environment. Dogs living in warm, humid environments may be at a higher risk than those living in cool, dry environments. Humidity and warmth are essential for bacterial growth. Items in the environment can also contribute to the onset of pyoderma; the biggest culprit being dog bowls! Plastic bowls are particularly good bacterial breeding grounds because they scratch very easily (even if you cant see the scratches to the naked eye), which leaves crevices which are difficult to fully clean, allowing for bacterial growth. When the dog touches the bowl, the bacteria rubs onto the skin, causing pyoderma. An unhealthy gut is also a huge contributing factor to the overcolonisation of bacteria, which can cause pyoderma. 70-80% of the immune system lays in the gut. When the gut is damaged, through the use of chemicals, pest control pharmaceuticals, poor diet or ingredients, or any other cause of gut damage, this can have a severe effect on the body’s ability to get rid of the over-colonised bad bacteria. This leaves the dog more vulnerable to pyoderma. Secondary infection is also one of the major causes of pyoderma. It can be a secondary infection arising from a poor skin barrier, poor gut flora, intolerences to food, and contact allergies from the environment. As well as these common health complaints, there is also a genetic mutation called the Fillagrin mutation – this is much like eczema in humans. Findings Here Breed predisposition may also be a factor in the onset of pyoderma, however more research in this field is needed. Breeds thought to be at higher risk of pyoderma include: Spaniels (ususally lip fold pyoderma) Pekingese Pugs Boxers Bulldogs Shar Pei Read more about genes and skin health here! Finally, stress could contirbute to a dog getting pyoderma. Just like in us humans, stress-spots are very much possible. This is down to the skin having developed it’s own HPA axis. When the body is under stress, the adrenal glands release, and flood the body with stress hormones. This sudden burst of hormones can cause pyoderma to form on the skin. Read more about the skin’s HPA axis here! How to Prevent Pyoderma Prevention of pyoderma is something that may be overlooked by many pet owners, but it can happen to any dog at any age, so it’s something to be mindful of. Using the Right Bowls In order to reduce the risk of bacteria against the skin on the face, and around the mouth, we need to be mindful of the bowls being used for food and water. Glass (modern Pyrex is great, but avoid vintage Pyrex due to the potential for lead contamination!) bowls are a fantastic option, but beware if your dog is likely to pick it up and drop it. Stainless steel bowls are also a good option. Avoid plastic bowls, and be cautious using ceramic bowls, due to the ease of cracking of the glaze, which could then harbor bacteria. Keeping the Gut Healthy As previously mentioned, 70-80% of the immune system lays in the gut, so keeping the gut healthy is incredibly important. There are many avenues to keeping the gut healthy. Feed a fresh diet where possible – dry food is very drying on the gut, and often contains ingredients that can contribute to Leaky Gut. Fresh food, whether it’s raw or cooked using one of our recipes balanced to FEDIAF, is high in moisture, so is better for the gut. Avoid using worm and flea pharmaceuticals – these act a lot like paint stripper on the gut, and contain damaging ingredients, not to mention the risk of seizures, ataxia, and other nasty side effects. Don’t over-vaccinate! The adjuvants used in vaccinations can be detrimental to gut health due to the content of heavy metals. Use a probiotic, and if needed, a mucilage herb. Our product Gut Gurdian is a great choice, combining three mucilage herbs, calming chamomile, and some good quality soil based probiotics. Keeping the Skin Clean Keeping skin clean and dry is very important – focusing on the chin and mouth area, wrinkles/folds in certain breeds, and armpits and groin areas. You may wish to use a hypochlorous based product, of topical probiotic product to clean with, such as Leucillin or Dew (Hypochlorous based), or Provilan LUCAA+ probiotic products. Ensure areas are thoroughly dried. Keep On Top of Allergies Allergy symptoms usually include itching – constant itching of an area will irritate the skin, and leave it open to bacterial infections, especially in the hair follicles. It’s important to work on finding your dog’s triggers, and eliminating them. Keep the Environment Clean Try to keep the dog’s living environment clean! A clean environment, means less risk of bacteria. Less bacteria in the environment, reduces the risk of transmission to a host. How to Support the Body If your dog has pyoderma already, there are some things you can do to support the body through recovery. Let’s take a look at some
Here at My Pet Nutritionist, acid reflux is one of the most common issues we come across in our consultations. Dogs with acid reflux may have it for a variety of reasons, from allergies to BOAS, and many other reasons in between. These dogs are often less tolerable of some generally preferred diets, so require a specific diet and supplement regime, which we will discuss here! A Bit About Acid Reflux Acid reflux is formally known as gastroesophageal reflux disease (GERD). When a dog eats, a mixture is formed in the stomach, comprising of stomach acid, salts and bile; this is called chime. Those with acid reflux suffer from the chime mixture entering the oesophagus. Acid reflux is a symptom of many underlying health conditions, and can be very uncomfortable. While acid reflux itself is not life threatening, it can lead to oesophageal ulcers due to repeated inflammation of the lining of the oesophagus, as well as the potential risk of aspiration pneumonia. Symptoms of Acid Reflux include: Bad breath Regular burping and regurgitation Tenderness of the stomach (bowing is the main sign of this) Constipation or diarrhoea Lack of appetite Lethargy Wheezing and dry coughs Weight loss Acid reflux is often caused by low stomach acid, contrary to what many may assume. Proton pump inhibitors are often prescribed under the assumption that the dog has too much stomach acid, however it’s often the exact opposite issue. This may seem an odd concept, however it becomes clear that when the stomach is lacking acid, it is unable to fully digest food at a high enough rate, so the food tends to sit in the stomach, which is then regurgitated. For more information on acid reflux, read our blog here! Diet When is comes to feeding a dog with acid reflux, it’s important not to feed processed foods. Processed foods such as kibble, are very inflammatory, which ultimately reduces stomach acid. A reduction in stomach acid can be a major trigger for acid reflux, as there’s less acid to digest foods. Fresh feeding for acid reflux dogs can be raw, or lightly cooked. Many dogs with acid reflux find it difficult to tolerate raw food, as the food sits in the stomach for a long time; when it sits in the stomach in chime, gasses are released, and the chance of reflux increases. Cooked food is often the best option. When feeding a cooked food, it is incredibly important to follow a balanced recipe, such as our recipes! Sticking to the leaner protein options such as the white fish recipe may be the best option, as feeding fattier proteins may cause more issue for dogs who are unable to digest efficiently. Acid reflux is often a symptom of allergies, so it’s important to get to the bottom of the dog’s allergies, and eliminate trigger proteins from the diet. To achieve this, an elimination diet should be carried out. Why not book in with one of our team for guidance through an elimination diet? Ensure there is plenty of fibre in the diet. Insoluble fibre increases gut and stomach motility, which is essential for those suffering from acid reflux. Some great sources of insoluble dietary fibre are: Broccoli Leafy greens Cauliflower Carrots Berries Findings Here Feeding a good variety of proteins (if allergy constraints allow), and a variety of plant matter can help ensure there are no vitamin deficiencies, which could contribute to acid reflux. In the human world, bariatric surgery patients often suffer with GERD, due to the inability to consume sufficient amounts of vitamins and minerals – nutritional deficiencies can impact our dogs too! Zinc deficiencies are common among acid reflux patients as it is thought that zinc helps protect the lining of the stomach. Findings Here Findings Here Working on getting to the bottom of any allergies and intolerances is important in helping relieve your dog of symptoms too! Allergies and intolerances are largely down to gut health, which causes a knock on effect on acid reflux. It’s also very important to choose the correct supplements to give your dog when suffering with acid reflux. Supplements The first, and most important supplement, or group of supplements we will be looking at, is those that aid gut health. Mucilage Herbs Mucilage herbs include Slippery Elm, Marshmallow Root, and Declycyrrhizinated Liquorice Root. These herbs are excellent for healing the gut, as they coat the digestive system. They not only help heal the gut, but they also soothe the oesophageal tract which is great for those suffering with acid reflux. Our probiotic and mucilage herb blend, Gut Guardian, may be perfect for your dog! Probiotics Probiotics are essential for a healthy gut. They help the gut microbiome flourish, which in turn aids digestion of foods, reducing the risk of chime sitting in the gut. Our aforementioned Gut Guardian supplement contains a great variety of clean probiotics, so may be a great choice for your dog! Findings Here Digestive Enzymes Some dogs, especially our acid reflux dogs, often suffer from poor digestion, due to insufficient amounts of the required digestive enzymes. When lacking such enzymes, food sits in the stomach in the chime mixture, which is them repeatedly regurgitated. Giving a good digestive enzyme may be pivotal to your dog’s recovery, or management of acid reflux. The two enzymes as play in this situation are Pepsin and Trypsin. Findings Here Rhodiola This is a herb, less commonly known in general, which contributes to responding to physical and mental stressors. As well as aiding those with diabetes, cancer, and anxiety, Rhodiola is great at helping the body cope with the physical stressors acid reflux brings. Findings Here Theanine Theanine is a non-protien amino acid which occurs naturally in tea. It plays a role in the prevention of acid refluc flare ups by increasing GABA activity, and reduce oesophageal sphincter relaxations. Together these reduce the symptoms of acid reflux. Findings Here If your dog has acid reflux, and you are unsure what to feed
Here at My Pet Nutritionist, we often help pet owners battle with oxalate crystals/stones in their pets. A diagnosis of any urinary stone can seem daunting, but that’s where we can step in to help! This is a handy guide to the ins-and-outs of Calcium Oxalate stones! What are Oxalate Stones? Oxalate stones, formally known as Calcium Oxalate stones, are formed of microscopic crystals of calcium oxalate. They’re the second most common type of urinary stone found in dogs, second to Struvite stones. If left untreated, oxalate crystals are one of the leading causes of kidneys stones. Males tend to get diagnosed with oxalate stones more often than females, and they’re more common in older dogs than they are in younger dogs. Some breeds are predisposed to Oxalate Stones. These include: Miniature schnauzer Yorkshire terrier Lhasa apso Bichon frise Shih Tzu Miniature poodle Chihuahua Jack Russel Findings Here Findings Here Symptoms of Oxalate Stones There are a number of symptoms caused by oxalate stones, including: Difficulty urinating Bloody or cloudy urine Smelly urine Frequent urination Distended abdomen Lack of appetite Changes in behaviour Lethargy Vomiting If your dog has such symptoms, it’s important to seek veterinary assistance. How Do They Form? Studies show that feeding a diet that causes high levels of urine acidity can contribute to the formation of oxalate stones. Research suggests that urine high in calcium, citrates and oxalates (these changes to urine are largely controlled by diet) can increase the risk of the dog having oxalate stones. Breed, and sex predisposition are huge factors in the formation of oxalate stones, alongside the aforementioned dietary factors. Findings Here Findings Here Diagnosis, and Getting Rid of Oxalate Stones When taken to the vet, the dog will have a blood sample taken, and a full blood panel will be run. A urinalysis will also be performed to check for increased levels of acidity, calcium, citrates and oxalates. If bladder stones are not able to be felt through palpation of the bladder, an x-ray may be performed to work out exactly what we are dealing with. Unfortunately, oxalate stones usually require surgical intervention, as they cannot be dissolved once formed. Like with Cysteine stones, smaller crystals may be able to be flushed out using urohydropropulsion, however as these crystals, untreated, can grow rapidly and cause urine infections, most veterinary surgeons would prefer to operate and remove all crystals as a first port of call. Findings Here Supporting the Body, and Preventing Oxalate Stones There are many ways we can support the body to prevent recurring formation of oxalate stones. Let’s discuss these! Probiotics Studies show that probiotics are effective at breaking down oxalates in the digestive system, so it’s wise to give a good, broad spectrum probiotic every day. Avoid high calcium, acidic, and high oxalate foods It’s incredibly important to keep the pH of the urine as alkaline as possible. There are certain foods we recommend to avoid feeding your dog if they have history of oxalate stone development. These include: Spinach (high in oxalates) Leafy Greens (the darker they are, the more oxalates they contain) Beets (high in oxalates) Citrus fruits (high in citrates and oxalates) Legumes (high in lectin, and oxalates) Beans (high in lectin and oxalates) Nuts and seeds (high in oxalates) Berries (high in oxalates) Increase moisture intake Always insure your dog is drinking plenty of water! A high moisture diet is also incredibly important, be it raw, or freshly cooked. You can also ‘float’ the food, by adding extra water to it. Check out our low oxalate recipe here! Limit sodium intake Another reason to avoid dry foods, is that they’re often high in salt. Salt is very dehydrating on the body, so it’s important to limit sodium intake. Findings Here Findings Here Findings Here Has your dog been diagnosed with Oxalate, of any other type of urinary tones? If the answer is YES, don’t hesitate to book a consultation with one of our team! Team MPN x
This year, tick infestations seem to be particularly bad. At My Pet Nutritionist, we have had many worried pet owners coming to us, regarding tick prevention, worrying about potential diseases the ticks their dogs are picking up may carry. This guide explains what ticks are, how to identify them, how the severity of tick bites differs depending on your location in the world, what diseases ticks can carry, and how to help prevent tick bites. We will also discuss the dangers of conventional tick treatments, and explain how to safely remove any engorged ticks. (Did anyone get the ode to Fantastic Beasts, and Where to Find Them?! Ticks are definitely not ‘fantastic’ beasts, however!) How to Identify a Tick Ticks are often mistaken for skin tags… or those latched on the stomach area, often mistaken for nipples! Ticks have very small heads, and large, shiny, rounded bodies. They have 8 legs, which protrude from around the head area. Ticks can be a variety of colours, from peachy-nude, to red, to dark brown, grey and black. They can be seen crawling across your pet’s fur, or engorged, in which case, only the large rounded body will be visible, with the legs also visible right next to the skin. We will talk about tick removal later in this article. Ticks in the UK In the UK, our tick population doesn’t tend to carry diseases which are deadly to healthy dogs, unlike other countries which have ticks carrying more severe diseases. We have around 20 species of tick in the UK. The most common species of tick in the UK are Castor Bean ticks (Ixodes Ricinus), Hedgehog ticks (Ixodes hexagonus), and Dog ticks (Ixodes canisuga), though deer ticks are sometimes picked up. Ticks in the Rest of the World Ticks in countries outside of the UK can be much more dangerous than those in the UK, to both humans and dogs. Paralysis ticks are an example – once engorged, Australian Paralysis ticks (Ixodes holocyclus) and the European Red Sheep tick (Haemaphysalis punctata) release a neurotoxin which causes paralysis in the host. Another of the more dangerous ticks is the Lone Star tick (Amblyomma Americanum) which can transmit ehrlichiosis in dogs, which can cause internal bleeding, and death. In humans, the Lone Star tick can cause Alpha-gal syndrome, which is a severe allergy to red meat, and products made from mammals. But What About Lyme Disease? Often carried by Deer Ticks, Lyme disease is the most common potential disease transmitted from ticks. In humans, Lyme Disease is a very debilitating condition, and has a huge affect on one’s quality of life. Humans affected, will likely be on very long courses, or even lifelong medication. Thankfully, Lyme Disease in dogs is much less of a worry! Dogs have a great ability to fight the bacteria causing Lyme Disease. In a study of Beagles exposed to Lyme disease, none of the adult dogs showed any symptoms! Puppies naturally have a less developed immune system, so the puppies in the study had around 4 days of mild symptoms, before their immune system fought off the bacteria! By keeping the immune system strong, we can reduce the risk of symptomatic Lyme Disease in our dogs! Feed fresh, and keep the gut healthy to help keep the immune system strong! Interesting fact: For transmission of Lyme Disease, a tick has to be engorged (attached to your dog, feeding) for 24-36 hours. If removed safely before this period, the risk of transmission is low. Findings Here How To Safely Remove a Tick First we’ll explain how NOT to remove a tick, as this is incredibly important to minimise the risk of disease transmission, and is a common mistake made by pet owners. The cardinal sin in tick removal, is smothering it. Never smother a tick in Vaseline, natural tick prevention, or any other product, and never attempt to burn them off. When you smother a tick, they let go as they are unable to breathe efficiently, however this also causes them to panic. When a tick panics, they regurgitate. Their innards, which could be hosting disease, would be expelled into your dog’s blood stream! If the tick is carrying anything untoward, it would be passed onto your dog! Now onto the SAFE removal of a tick! There are 4 tools you can use! Let’s take a look at each of these! Tick Twisters: These are plastic tools, with a forked end. Simply slide the tick between the forks, right by the skin, so the tick’s head is in the tool, and twist it. The twisting action causes the tick to let go. Tick Keys: These have a large hole, with a very thin opening at the end. Simply hook the tick into the thinnest part of the hole, and pull away from the skin. This pulls the tick from the skin. Tick Lassos: These are pen-like items, with a retractable wire loop at one end. Hook the wire over the tick, and retract it so the tick cannot move. Gently twist, and pull it away from the skin. Tweezers: This is probably the least effective method, but perhaps slightly more accessible if you don’t have a tick tool at home yet (it’s a great idea to add one to your dog first aid kit!). Fine pointed tweezers work best. Pinch the tick with the tweezers as close to the skin as possible, and gently lift the tick away. Be sure to remove the head! Once removed, spray the area with Leucillin, or similar natural antiseptic spray. How to Prevent Ticks There are a number of natural tick prevention methods available. A layered approach is best; an internal product, an external product, and perhaps a repelling collar. Internal products often include herbs such as neem leaf, peppermint leaf, yucca, ginger, fenugreek, lemon balm, and garlic. These all make the dog unattractive to ticks. Fresh garlic is a great internal preventative, in the correct amounts for your size of dog. Do
Has your dog had, or been recently diagnosed with gallstones? While they’re not a massively common condition, we do help many dogs with gallstones, here at My Pet Nutritionist. Understandably, owners may be concerned upon news of this diagnosis, so we hope this article helps you understand the condition, and puts your mind more at ease. What Are Gallstones? Gallstones can be found in the gallbladder; a pear shaped organ, located just beneath the liver. The gallbladder is a very important part of the digestive system. It stores bile, which is produced by the liver, and is responsible for digesting fat in the diet. Gallstones are balls of matter, usually made of cholesterol, and hardened bile that form in the gallbladder, blocking it’s ability to secrete bile. Gallstones can be any size from the size of a dust particle, to the size of a ping pong ball! Findings Here Symptoms of Gallstones There are a multitude of symptoms that may present when your dog has gallstones. Let’s take a look at these! ‘downward dog’ yoga pose; this shows a painful abdomen Nausea and vomiting Rapid weight loss Lack of appetite Diarrhoea; can be bloody Jaundice (a yellow tinge to the skin) High body temperature If your dog has any of, or a number of these symptoms, raise this with your veterinarian. How Do They Happen? Poor Digestion Pets with digestive issues may be at risk of gallstone formatsion. Poor digestion can lead to low stomach acid, which can massively affect gallbladder health. In order for the gallbladder to release bile, the stomach needs to be acidic. Lack of stomach acid causes a decrease in bile production. Findings Here Poor Diet Those eating a high fat diet may be at a higher risk of developing gallstones, as the high fat content puts pressure on the gallbladder. When the gallbladder is under the pressure of high levels of fat, it becomes inflamed, and production of the necessary amounts of bile becomes difficult, leading to the formation of gallstones. Feeding a dry food may also contribute to the formation of gallstones, as the fat content of may dry foods, on a dry matter basis, is often high/concentrated. Most kibbles are sprayed with fats and oils at the end of the production line to enhance flavour and palatability. Findings Here Stress Stress hormones have a huge impact on the development of gallstones. When stressed, the liver releases higher amounts of cholesterol, due to the higher production of energy during periods of stress or anger. This increased amount of cholesterol can easily lead to gallstones, as the gallbladder is unable to produce sufficient amounts of bile to digest the excess cholesterol. Findings Here How Are They Diagnosed? If gallstones are suspected in your dog, your veterinarian will want to carry out various tests. An X-Ray will be obtained of your dog’s stomach area, to visually detect any potential masses in the gallbladder, and potential cirrhosis of the liver. A urinalysis will be performed; this is when the vet takes a urine sample and analyses it to look for excess fats in the urine. These results may flag an issue with the gallbladder. Finally, bloodwork will be carried out to look for any abnormal values which may point toward the reduced function of one of the body’s organs. What Negative Effects Can Gallstones Cause? Cholestasis occurs as a result of gallstones blocking the bile duct entirely. This blockage requires surgical removal. When the gallbladder is blocked, absorption of vitamin D and Calcium becomes poor, as well as the aforementioned symptoms. Acute Pancreatitis is also a risk posed to those with gallstones. Gallstones can exit the gallbladder and cause blockages in the bile duct, which ultimately blocks pancreatic enzymes from entering the small intestine. These enzymes are forced back into the pancreas, which creates immense inflammation to the organ, leading to the onset of acute pancreatitis. Findings Here Findings Here What Treatments Are Available? Generally speaking, surgery is usually the main option when treating a dog with gallstones. Some mild cases may get away with having IV Therapy, whereby the dog is hooked up to an Intravenous drip, designed to flush the gallstones from the gallbladder. The patients will usually be prescribed a high protein, low fat diet moving forward… this is where supporting the body naturally comes in! Read on! How Can We Support the Body Naturally? Feed Fresh As with any condition, we always recommend feeding fresh food, here at My Pet Nutritionist; whether that’s raw, or cooked. Balancing the fat content in Fresh food is much than in dry food, and is not sprayed with fats and oils during production, adding to the overall fat content. Fresh food is also high in moisture, and generally better for digestion and gut motility than dry food, making it the ideal option for those with gallstones in their medical history. Feed Low Fat Feeding low fat is also essential for those suffering from gallstones, due to gallstones being solidified lumps of cholesterol. As the gallbladder is unable to produce enough bile to digest the fats consumed in the diet, fatty deposits will begin to build up, which is especially dangerous for the body’s organs. Find our low fat recipes below! Low Fat Fish Low Fat Venison Low Fat Horse Low Fat Kangaroo Dandelion Dandelion has many health benefits for your dog! One benefit being that it’s a fantastic digestive aid. When suffering from gallstones, digestive support is crucial. Dandelion stimulates the production of digestive juices, which are ever so important when it comes to gallbladder health, and gallstone prevention. Dandelion is also a great natural anti-inflammatory. This is beneficial for those suffering from gallstones or poor gallbladder health in general, to reduce the risk of acute pancreatitis occurring. The root of the dandelion plant is also a diuretic, bringing benefits to the liver, which includes increasing circulation in the liver, resulting in an increase in bile production. Findings Here Burdock Root A more unusual vegetable, burdock,
Immunity is no doubt at the forefront of most pet owner’s minds. Everyone wants their pets to live a long and healthy life, so keeping a strong immune system is essential. Here at My Pet Nutritionist, we help many pet owners through their own experiences of disease in their pets, so we thought we would put together this blog on the cornerstones for a strong immune system in your pets. 1. Gut Health Gut health is key to general health of all species, whether it be human, canine, feline, or even smaller furry pets! Virtually all aspects of health can be improved through good gut heath. Around 70% of the immune system is found in the gut! Quite a staggering figure, but a very important fact to keep in mind when it comes to our pets’ health. In an unhealthy gut, the immune system becomes massively impaired, leading to a potential multitude of health issues, including those allergy dogs we so often help here at My Pet Nutritionist. Many things can damage the gut, including chemical flea and worm treatments, poor diets which are processed and/or high in ingredients containing lectin, contact with household and garden chemicals and much more. It’s imperative to gut health, to feed fresh, and limit the exposure to all toxins! Using a mucilage herb for those with damaged guts, helps to heal the gut; these include slippery elm, marshmallow root, and deglycyrrhised liquorice. Teaming these with a probiotic allows the gut to flourish, as a damaged gut will leak the good bacteria which forms a large part of the immune system. Gut Guardian 2. Methylation DNA Methylation is a very important chemical process within the body. This process includes the chemical modification of DNA during replication of cells. Gene expression can be altered through methylation too. So, why is this process an important part of keeping the immune system strong? Various malignant cells, including those for lymphoid cells (produces immune cells B, T and NK) and myeloid cells (related health issues, such as Mast Cells) replicate through a process called hematopoiesis, making these cells ‘hematopoietic stem cells’ (HSCs). Myeloid cells are not ones we want replicating in the body, as they can lead to various types of tumour. Here’s where the process of Methylation comes in to play! Methylation has the ability to regulate HSC differentiation – in other words, it reduces the risk of the Myeloid cells replicating, and forming tumours, but increases differentiation of lymphoid cells. For more information on the types of cells involved in immune responses, read our blog here! Findings Here Findings Here Findings Here 3. Healthy Brain and Endocrine System The Endocrine System is what keeps the body’s organs in good health, through homeostasis. The endocrine system and immune system used to be thought to work independently from one another, but more recently, it was discovered that the two systems work hand in hand to keep the body healthy, and control infection. The immune system uses a mixture of immune receptors and cytokines to fight infection, and the endocrine system uses hormones to regulate metabolism in the body’s organs. As an example, one of the most important regulations aided by both systems, is the metabolism of glucose. Insulin is produced by the endocrine system to regulate glucose levels in the blood, and helps the body to fight infection. Cytokines aid the body during glucose spikes by increasing responsiveness of the peripheral organs to the endocrine system. When the organ becomes more responsive to the signals from the endocrine system, greater amounts of the required hormone can be produced. The brain produces so many important hormones for health of the body, and to help fight a variety of infections, so it is important to keep the brain healthy and free from inflammation. Supplementing your pet’s diet with plenty of omega 3 is a great way to keep inflammation down. To read more about the endocrine system, and the importance of hormones, read our blog here! Findings Here Findings Here 4. Circulation and Lymphatics The lymphatic and circulatory systems are an important part of immunity, and keeping the immune system strong. The lymphatic system is responsible for draining excess fluid from bodily tissues, removing cellular waste, absorption of fat soluble vitamins from dietary sources, and helping to fight infections. The circulatory system works with the lymphatic system to transport the cellular waste and excess fluid around the body, and away from the relative organs. The interstitial fluid (found between tissues) is what provides the body’s cells with important nutrients, and a way of removing any waste from the cells. The lymphatic system acts as a taxi for antigens and antigen-presenting cells to transport them through the body to places of infection. This enables the antigens to fight the infection in question, and expel waste. Findings Here Findings Here 5. Detoxification Finally, detoxification is essential for immune health. The body is exposed to a host of toxins, just by going through daily life. We live, generally, in a very toxic world, so detoxifying the body is essential. Detoxification aids methylation, which as discussed above, is a very important process for a strong immune system. Liver Guard Heavy metals can be picked up and consumed very easily in our pets – traces can be found in food, and heavy metals are also in abundance in vaccinations. Those who have received vaccinations during their lives, whether only one has been given at an appropriate age as a puppy, or they’re given regularly (if given regularly, over vaccination occurs, making the risk of vaccinosis higher; read more here) the likelihood that your pet has heavy metals in the bloodstream is high. Heavy metals disrupt metabolic functions in vital organs, as well as reducing the ability to efficiently absorb vitamins and minerals from dietary sources. Detoxification can be achieved through feeding a fresh, preferably organic diet, minimising exposure to environmental and veterinary toxins, occasionally offering Epsom salt baths, supplementing the diet with milk thistle (this
A diagnosis of Diabetes in your pet can feel quite daunting. We decided to put together this guide on diabetes in pets, to bring all you may need to know about diabetes, and caring for a diabetic pet, into a handy, bitesize guide! What is Diabetes? Diabetes is a condition causing blood sugar levels to become too high. There are three types of diabetes; Type 1, type 2, and Diabetes Insipidus. Type 1 is found in around 0.2 to 1% of dogs, but type 2 diabetes is not found in dogs; it is however, found in cats. Diabetes Type 1, is most commonly found in adult dogs between the ages of 6 and 9. Diabetes Insipidus is another type of diabetes, unrelated to type 1 or 2, but with similar symptoms. Findings Here Symptoms of Diabetes Symptoms of diabetes in pets include: Polydipsia (excessive water consumption; read more here!) Polyuria (excessive urination; read more here!) Increased appetite Weight loss (often rapid) Recurring skin and urinary infections Clouded eyes A dog with diabetes may present with any number of these symptoms, so if your dog is displaying one or more of these, it’s best to have a full vet check. Findings Here What Causes Diabetes? A huge part of the cause of diabetes in dogs, is down to genetic predisposition. Breeds predisposed to the potential to develop diabetes include: Miniature schnauzer Dachshund Beagle Poodle Samoyed Keeshond German Shepherd Golden Retriever Labrador Retriever Bichon Frise Pug Cocker Spaniel Diabetes can also be caused by other ongoing medical problems. It can be a secondary condition to Cushing’s Disease, Pancreatitis and obesity. Those suffering with pancreatitis flare ups are at risk of diabetes due to the damage on the organ, caused by regular periods of intense inflammation. The pancreas secretes insulin which regulates blood sugar levels. When insulin is not able to be produced due to damage to the pancreas, blood sugar spikes occur, which leaves dogs at a high risk of diabetes. 30 to 40% of dogs with diabetes, also have pancreatitis. Obesity, like in humans, is a common predecessor for diabetes as it contributes to insulin resistance. Resistance to insulin, means less control of blood sugar levels. Findings Here Diagnosis of Diabetes To test for Diabetes, your veterinarian will take bloods and urine samples. In the urine sample, they will test levels of glucose and ketones. If there is a significant abnormality in these results, the blood glucose level will be tested. If glucose levels are very high in the blood sample, and found in the urine sample, a diagnosis of diabetes can be made. During testing for diabetes mellitus (Type 1), other significant markers for other conditions may be found, so your veterinarian may start treatment for other conditions as well as diabetes. If your dog’s urine is extremely dilute, diabetes insipidus may be a diagnosis your vet may consider. Findings Here Monitoring, and Medical Intervention Insulin Therapy After diagnosis, the first thing your vet will work out, and prescribe, is the right insulin dose for your dog. The vet will teach you how to give an insulin injection, either by syringe, or VetPen. These will need to be given regularly alongside monitoring, to ensure your dog’s blood sugar levels stay consistent and within a normal range. Findings Here Monitoring Glucose Levels Traditionally, your vet will teach you how to monitor urine glucose levels at home. Urine can be tested using urine strips, just as you would in the human world. The vet may also teach you to test your dog’s blood glucose levels. They will provide you with a portable glucose meter, which you will use in tandem with blood test strips. Bloods may be taken, and analysed regularly by the vet to keep an eye on blood glucose levels and ensure the insulin dosage is correct. More recently, some veterinary practices have been offering the Freestyle Libre device worn by many human diabetics. This is a device inserted into and attached to the skin, which reads blood glucose levels. When the owner needs to check glucose levels, they simply use their accompanying mobile phone application which connects to the device. This is an expensive option, but very fail safe, and easy. Findings Here Findings Here Spaying Females Your veterinarian will recommend you spay your female dog if they are diagnosed with diabetes. One of the female sex hormones, called progesterone, can sadly interfere with insulin usage in the body, which could cause a blood sugar spike. Findings Here Supporting the Body Naturally Diet As with anything, we always recommend feeding a fresh diet. Why is this so important for diabetes sufferers? The carb content in dry foods causes a spike in blood sugar levels. Forcing a raised blood sugar level on a diabetic dog will put a huge amount of pressure on the organs, and can cause hospitalization. When looking at the ingredients list of dry foods, there may be very few ingredients which appear to be carbohydrates; however, these do add up! The carb content of dry foods isn’t specifically listed, only protein, fat, moisture and ash. If you add those up, and deduct from 100, you will get the percentage of carbs in the food. Most dry foods are between 20 and 70% carbs! Three very important components of a diabetic dog’s diet, are fibre, fat, and protein. Fibre, fat and protein help to stabilise blood sugar levels as the consumption of these macronutrients causes the digestion of carbs to slow down, ultimately slowing down their absorption into the blood. Because the absorption of the sugars from carbohydrates is slowed, blood sugar levels stay more controlled, and are more unlikely to spike. Findings Here The moisture level of fresh food, also helps keep the urine suitably dilute, and not concentrated in glucose or ketones. You will need to keep the amount fed each day the same, as this is what your dog’s insulin dose is based upon. If the dog is fed more than normal, the
At My Pet Nutritionist, we often get enquiries about dogs suffering with urinary crystals or bladder stones. One of the types of crystal often diagnosed, is the Cysteine crystal. What are Cysteine Stones? There are 4 main types of bladder stone/crystal; Struvite, Calcium Oxalate, Urate, and Cysteine. Cysteine stones are uroliths (solidified lumps of crystalloids) which can form in the bladder, urinary tract, or kidneys. Of the four stones, Cysteine stones are incredibly rare, with only around 1% of diagnoses being Cysteine. While these stones can happen in female dogs, they are most common in males. Learn more about the different types of stone in our blog here! How are Cysteine Stones Formed? The amino acid, Cystine, is made by the body after synthesis of methionine. Cysteine can also be found in some higher protein foods. It is reabsorbed by the kidneys, but when the kidneys are unable to absorb it, a condition called cystinuria occurs. When this happens, the cystine becomes very concentrated in the urine, which causes the formation of Cysteine bladder or kidney stones. As with each type of urinary stone, there are some unique characteristics associated with it; these stones only form in acidic urine. Dogs with more alkaline urine will not form this stone. The risk of cysteine stones forming, may also be down to genetic abnormalities. Findings Here Findings Here Symptoms of Cysteine Stones Though similar for other stone types, some symptoms your pet may show are: Frequent, sometimes bloody urine Painful urination Excessive drinking Nausea and vomiting Breed Predisposition Some breeds of dog are genetically predisposed to Cysteine stones, and may require regular treatment, as this type of stone is often a recurrent issue. Breeds predisposed to Cysteine stones include: Basset Hounds Dachshunds Newfoundlands (unusual female cases have been recorded in this breed) Bullmastiffs English Bulldogs Irish Terriers Findings Here What Can the Vet Do? Surgery Often required for those with larger stones, surgery is a very common path to take when battling Cysteine stones. The surgical procedure is called a Ureteroscopy, during which a very small instrument is passed through the bladder and up the Ureter, pushing the stone out in the process. Alternatively, the pet may be opened up, and large stones causing blockages will be removed by hand. Findings Here Non-Surgical Removal There is a non-surgical option available for those with very small cysteine stones; this procedure is known as urohyrdopropulsion. This procedure is usually most successful on medium to large dogs, and involves two catheters being placed in the dog; one up the urethra, and the other in the urethral lumen. A finger is inserted into the rectum to push against the urethra, causing a build up of pressure and a tight seal. Once a tight seal is made, saline water is flushed through the catheters, and the bladder is palpated, flushing the small stones out. Although this method requires anaesthesia, it is preferred for smaller stones as it is much less invasive than surgery. Findings Here How Can we Support the Body? Diet Diet plays a huge role in the prevention of Cysteine stones. With these stones, its advisable to feed a normal amount of calcium, but slightly lower protein, and also low salt (to avoid water retention/dehydration). As well as these specific nutrient requirements, it is imperative that your dog’s diet includes as much moisture as possible! Moisture in the diet will help flush the bladder; feeding a dry food would dehydrate the dog, and could worsen the issue. Feeding a fresh food is very much recommended for any bladder stone, including Cysteine! Findings Here Find our recipe suitable for dogs suffering from cysteine stones here! Supplements Omega 3 in the form of Alpha Linoleic Acid (ALA) is thought to inhibit cysteine crystal formation, due to it’s anti-inflammatory, and antioxidant properties. ALA can be found in leafy greens, nuts (avoid peanuts, and macadamia nuts), and animal fat. Findings Here Selenium has been proven to reduce the volume of cysteine crystal formation. When looking for a supplement, ensure it is as pure as possible. Findings Here Bonus Factoid: Cystinuria Type 3 Cystinuria Type 3 is a cysteine based, androgen dependent disease which means it only affects entire males. Bulldog breeds are particularly prone to this condition. The veterinary treatment is the same as standard cysteine stones, regarding urohyrdopropulsion, however in order to stop this painful condition from recurring regularly, the only method of prevention is castration. Neutering should be discussed with your veterinarian, and performed at the right time if your dog is a frequent sufferer of Cystinuria Type 3 flare ups. Findings Here If your dog has been suffering with recurring cysteine stones or crystals, consider booking in with one of our team! Team MPN x
Megaoesophagus is a challenging condition to care for, and a commonly discussed topic in the dog care world. Here at My Pet Nutritionist, we are often asked about how is best to care for a dog with Megaoesophagus, so here is our guide to megaoesophagus, and how to support those with it. What is Megaoesophagus? Often shortened to ME, Megaoesophagus is a condition which affects the oesophagus. The oesophagus is part of the digestive system, and one of the first body parts to be used in digestion. It can be found behind the trachea (windpipe), running down through the chest cavity between the heart and the spine. The oesophagus pushes food from the throat, to the stomach, where it is digested, by a process called peristalsis. Peristalsis is a wave-like series of contractions which squeezes food through the tube. When a dog has megaoesophagus, the oesophagus is dilated, which ultimately causes a lack of motility due to poor conformation and the inability to carry out peristalsis, so food is unable to reach the stomach, and the dog is unable to benefit from nutrients in the food. Megaoesophagus can occur in any breed of dog, and at any age, however some breeds are more at risk than others due to predisposition. These include: German Shepherd Shar Pei Newfoundland Great Dane Miniature Schnauzer Greyhound Labrador Findings Here Findings Here Symptoms of Megaoasophagus Regurgitation: probably the first symptom owners recognise. Because peristalsis is unable to occur, food sits in the oesophagus in the chest cavity, which results in it being ejected through the throat, and mouth, undigested. Aspiration pneumonia: a major health complication, and can be a sign that the dog has a dilated oesophagus. The dog may aspirate during regurgitation, causing major breathing difficulties and lung infections like Pneumonia. Lack of appetite: common in ME cases, dogs will often decide they’d rather not eat due to the discomfort caused by the food they’ve eaten sitting in the chest cavity. Extreme hunger: on the other end of the scale, the dog may seem constantly very hungry, because they are not receiving any nutritional benefits from the food being consumed. Frequent swallowing or air licking: dogs will often show these signs as they are unable to move food from the chest cavity, making them feel nauseous. Coughing: can occur as the dog attempts to move food from the chest cavity. Raspy breathing: this often occurs due to inflammation in the chest area, caused by the stuck food. Weight loss and stunted growth: as the dog is unable to make use of the nutrients from the food (as the food cannot get to the stomach to be digested), weight loss is very common, and growth in puppies is stunted. Smelly breath: the gasses from food stuck in the oesophagus can cause severely smelly breath. Drooling: often a sign of nausea, drooling is common in dogs with ME. Findings Here Causes of Megaoesophagus It is unclear as to how the majority of cases are caused. ME can be congenital (present from birth), hereditary (passed genetically from parents), or acquired (developing during life, but not genetically inherited). One potential cause of ME, is as a secondary effect of Persistent Right Aortic Arch; which is one of the most common vascular diseases in dogs, and causes the tightening of a ring around the oesophagus. Tumours in the oesophagus can be a cause of ME, as the tumour causes an obstruction, and changes the structure of the muscles in the tube, which then dilates it. Trauma to the oesophagus, spinal cord, or brain is often a trigger, as soft tissue damage heals with scar tissue, which effects the motility of the oesophagus. Parasitic infections are thought to be able to cause ME too, as the parasites latch onto the walls of the oesophagus, causing damage to the muscular structure. Myasthenia Gravis is a neuromuscular condition whereby generalised muscular weakness occurs in the body. This can also affect the muscles involved in peristalsis. Toxin exposure is a large potential, too. Toxins have so many poor effects on various parts of the body, and bodily processes. Its always best to keep toxins to a minimum by minimally vaccinating, using natural pest preventions, using natural household products, and feeding a fresh diet. There are also various studies to suggest that hormonal disorders regarding the thyroid can be a contributing factor to ME cases, including Hypothyroidism, Hyperthyroidism, and Hyperadrenocorticism (Cushing’s Disease). Findings Here Findings Here Findings Here Findings Here How is Megaoesophagus Diagnosed? If your dog is experiencing any of the symptoms listed above, it is imperative that you get them checked out by a veterinarian. The typical veterinary test for diagnosis of ME, is the Videofluoroscopic Swallow Study (VFSS), whereby the vet is able to see a live view of the scan being performed, so they are able to watch the path taken by food and liquid given before the study is carried out. They can see how efficiently it moves from the throat to the stomach. Findings Here What Conventional Treatments are Available? The vet may offer surgery to help improve your dog’s quality of life, however it is unlikely that surgery will completely cure the problem. The surgery will reduce the risk of aspiration pneumonia, which is a life threatening disease in itself, and may help to improve motility of food to the stomach. A gastric feeding tube may also be offered to your dog – this is a tube implanted directly into the stomach, through which food can be given, in order to completely skip use of the oesophagus. Food will not be regurgitated, however regurgitation of saliva will still occur. The final treatment your vet may suggest, is medication – there are a few medications which may be trialled, or even a botox injection into the lower part of the oesophagus, to help stabilise it. Findings Here What Can we do to Support the Body? There are many ways in which we can support those with ME.
At My Pet Nutritionist, Cushing’s Disease is a big topic. We help a lot of dogs with Cushing’s Disease, and so we have created this essential guide to supporting the body with Cushing’s Disease. What is Cushing’s Disease? Cushing’s Disease, formally known as hyperadrenocorticism, was first diagnosed in 1912, by an American neurosurgeon named Harvey Cushing; hence it was informally named Cushing’s Disease. Cushing’s Disease is caused by too much of the hormone, cortisol being produced by the adrenal glands in the kidneys. Cortisol is a steroid hormone, and is responsible for regulation of various important bodily functions, such as immune response, and metabolism, as well as stress responses. Cortisol floods the body during stressful situations, in response to the stressor, which reduces risk of negative impacts during a flight or flight situation. Findings Here How Does Cushing’s Disease Happen? It is thought that predisposition for Cushing’s could be inherited genetically, and there are various breeds that are predisposed to Cushing’s, including: Poodles (and crosses) Yorkshire Terriers German Shepherds Boxers Maltese Labradors Cocker Spaniels Dachshunds Boston Terriers Staffordshire Bull Terrier There are three different medically underlying causes for Cushing’s Disease. Let’s take a look at these! Prolonged Use of Steroids Both topical and oral steroids used excessively, can lead to Cushing’s Disease. This type of Cushing’s is called Iatrogenic Cushing’s. Steroids contain a synthetic variation of cortisol, which on top of the body’s natural production of cortisol, leads to an overwhelming amount of cortisol, causing Cushing’s. Findings Here Findings Here Adrenal Gland Tumour There are two types of tumour which could form on the adrenal gland, causing excessive cortisol production. Adenomas are benign tumours, which could be surgically removed, are the better of the prognoses; removal is usually successful. Carcinomas are malignant tumours, which can have surgical interventions, but the prognosis is much more negative, and aggressive treatment may be required. Findings Here Findings Here Pituitary Gland Tumour A huge proportion of Cushing’s cases are caused by tumours on the Pituitary Gland. The Pituitary Gland is located at the base of the brain, and secretes a hormone called ACTH, which stimulated the adrenal glands to produce Cortisol. When there is a tumour present on the Pituitary, more ACTH is secreted, which results in overproduction of Cortisol. These tumours may be benign or malignant, and may be microscopic, or large. The larger the tumour, the more neurological signs there will be. Findings Here Findings Here Symptoms of Cushing’s Disease There are a variety of symptoms of Cushing’s Disease, which include: Lethargy Increased appetite Weight gain Excessive thirst Excessive urination Poor skin/baldness Bloated appearance Calcinosis Cutis Difficulty healing from minor wounds Hyperpigmentation (dark spots) Recurring bladder infections How is Cushing’s Disease Diagnosed? There are a number of tests used when veterinarians test for Cushing’s Disease. The most common test is the ACTH Stimulation Test, during which a blood draw is taken from the dog, before ACTH is injected into the dog, and a second blood draw is taken some hours later. The two blood samples are compared for levels of cortisol. This is a very effective method, and cost effective. A Low Dose Dexamethasone Suppression Test can pinpoint exactly what is causing the Cushing’s Disease, if Cushing’s is present. In this test, a small amount of Dexamethasone (synthetic cortisol) is injected into the dog. In a healthy dog, ACTH production slows down to regulate the amount of cortisol produced by the adrenal gland; in a dog with Cushing’s, ACTH production would continue, causing raised levels of cortisol in a follow-up blood sample. To check the adrenal gland for swelling or visible tumours, your veterinarian may also run an ultrasound as the adrenal gland will be visible on this. Supporting the Body Diet Feeding a fresh food diet is very important, as with any condition! That could be raw, or cooked, balanced to one of our recipes. A low fat diet may be beneficial because fat and cholesterol levels in the body are increased when in the presence of excessive cortisol. When raw feeding, the organ being fed as part of your 10% offal, contributes to the support of that organ in the body; so feeding kidney may help support the dog’s kidneys. Supplements Omega 3 Omega 3 has an anti-inflammatory effect throughout the body, so is a very important addition to any dog’s diet, especially one suffering from disease, which could be worsened through inflammation. Not only are they anti-inflammatory, but Omega 3 also play a role in the brain’s production of neurotransmitters, which may be beneficial for Cushing’s sufferers. The effect omega 3 has on the brain is also shown to aid the reduction of mental stress. Findings Here Probiotics Cushing’s sufferers can suffer from poor gut health. Gut Dysbiosis is a concern among those diagnosed with Cushing’s, so giving probiotics is a great idea. These may ne teamed up with a mucilage herb such as slippery elm, or marshmallow root. our supplement below. Gut Guardian Findings Here Milk Thistle Particularly useful for patients with Cushing’s caused by a tumour, the active ingredient in Milk Thistle, Silibinin, has been proven to decrease tumour growth, and lower levels of cortisol. This supplement is also great for detoxing the liver; though that’s a topic for another day! You can read more on the liver here! Findings Here Liver Guard Melatonin and Lignans Melatonin and lignans are often used in combination with one another to help Cushing’s Disease patients. Melatonin is great for regulation of hormones. Regulation of cortisol is incredibly important in this situation, so melatonin may be a great option. Circadian rhythms are also maintained by melatonin. Lignans can be found in flax seed hulls, and mimic phytoestrogen. Phytoestrogen plays a large role in reduction of hormone-dependent tumours, as well as managing skin health. Adding lignans into the diet may aid Cushing’s sufferers, especially those suffering from a pituitary or adrenal tumour. Findings Here Findings Here Findings Here Complementary Therapies Acupuncture Acupuncture is great to reduce inflammation in the body, and
Here at My Pet Nutritionist, we deal with a huge amount of dogs with a variety of allergy symptoms. Some of our clients dogs have been diagnosed with Mast Cell Activation Syndrome (MCAS), which is an incurable disease, presented as repeated anaphylactic symptoms. What are Mast Cells? Found in the epithelial and mucosal tissues throughout the body, Mast Cells help regulate the formation of new blood cells, eliminate bacteria and parasites, and vasodilation as well as bone growth, and mineral homeostasis. Mast Cells also regulate cell function in various cell types, including: Dendritic cells Macrophages T Cells B Cells Fibroblasts Eosinophils Endothelial Cells Epithelial Cells While they’re very important parts of the body’s tissues, Mast Cells do produce and release substances which can be harmful in large quantities, including: Histamine Leukotrienes Heparin Proteases Prostanoids Cytokines Chemokines Growth factors What Does Mast Cell Activation Syndrome look like? There are a variety of symptoms associated with MCAS, including: Swelling of the body, either localised to one area, or general swelling. Nausea and vomiting Acute diarrhoea Hives Reduced/low blood pressure Difficulty breathing Difficulty swallowing Inability to stand or walk properly (may seem ‘drunk’) If any of these symptoms shows, it is imperative to seek veterinary attention immediately. If these symptoms occur regularly, then your dog may need to undergo tests for Mast Cell Activation Syndrome. What Causes Mast Cell Activation Syndrome? It is unclear what causes MCAS to develop. It is often an idiopathic condition – meaning it happens without clinical reason. As it’s a condition related to allergies and intolerances, it’s important to discover, and eliminate these triggers from the diet, to reduce the risk reaction. One study suggests a possible link to the onset of MCAS, in patients with underlying immune disorders. Findings Here How Does the Vet Test for Mast Cell Activation Syndrome? Blood tests will be carried out on your pet, to check for any elevated levels of histamines (which are released in the presence of a foreign body), tryptase (the markers of degeneration of mast cells, often produced during anaphylaxis), and prostaglandins (fatty compounds with a hormone-like effect in animals, which regulated inflammation). If one, or all of these are present in abnormally elevated amounts, a diagnosis of MCAS may be given, particularly if these episodes are regular, and any prescribed antihistamines calm symptoms down. Findings Here The veterinarian may prescribe histamine 1 and 2 blockers, mast cell inhibitors, mast cell stabilisers, NSAIDs, immune suppressants, or other pharmaceuticals, which inhibit the production of histmaines and tyrosine. One note to remember; some pharmaceuticals block DAO (Diamine Oxidase), which is the enzyme which breaks histamine down. We need histamine removed from the body as soon as possible so this is something to discuss with your veterinarian. How Can we Support the Body? Diet At My Pet Nutritionist, we are all about feeding a fresh diet, whether it be raw, or lightly cooked. Your chosen diet MUST be low histamine. Avoid fermented foods like kefir, sauerkraut, and ACV as these are high histamine, and avoid high histamine plant matter such as spinach, pumpkin, strawberry, and avocado. If making bone broth for your dog, replace the ACV with lemon juice for a lower histamine option! Read more about Mast Cell conditions, and low histamine diets here! So, why is fresh food best for those diagnosed with MCAS? Fresh food doesn’t contain unnecessary bulking ingredients, such as rice, maize/corn, other grains, legumes or nightshades. These ingredients all cause gut damage and/or are biologically inappropriate, and can be a major histamine release trigger. Fresh food is minimally processed. Ultra processed ‘dog food’ is often contaminated with glyphosate, and Advanced Glycation End-Products (AGEs), which are both damaging to the gut. It’s much easier to work on allergies and intolerances, using fresh food. This is important as we need to keep intolerances under control. Keep the Gut Healthy As with all potential allergy related issues, we need to keep the gut healthy! The gut microbiome is incredibly important to keep immunity strong, and reduce the risk of foreign particles being detected in the blood stream, having leaked from a gut with poor integrity. Any leaked particles will be targeted by histamine responses, which will increase the risk of a MCAS flare up. Some gut health supplements include slippery elm, marshmallow root, Deglycyrrhizinated Liquorice Root. These should be paired with a good probiotic. The My Pet Nutritionist Gut Guardian supplement is perfect for dogs requiring gut work! Gut Guardian Work on allergies Ensuring any potential allergies or intolerances are under control is essential! Those suffering with any Mast Cell related conditions must have their histamine levels under control at all times, to reduce the risk of a flare up. As MCAS is heavily related to anaphylaxis, it is absolutely paramount that allergens are completely eradicated from the dog’s diet, and lifestyle. In order to eradicate the allergens, an elimination diet is to be carried out, whereby one single protein is fed for numerous weeks, and is eliminated from the diet if the dog continues to worsen. Once some safe proteins are established, it’s important to stick to feeding only these proteins. Read more on elimination diets here. Supplements As well as the aforementioned gut healing supplements, there are a number of other supplements which may help support the body. CBD: mast cells have cannabinoid receptors (like most cells in the mammalian body), which when inhibited, causes their production to be downregulated. Findings Here Findings Here Findings Here Quercetin: found in various fruits, green vegetables and stinging nettles, quercetin is a natural antihistamine as it downregulates the enzyme responsible for converting histidine to histamine. Quercetin also reduces production of prostaglandins and histamines as it inhibits the cells responsible for their release. The inflammatory cytokines which cause inflammation as a large part of MCAS, are also inhibited, which decreases their production. Findings Here Findings Here Findings Here Curcumin: this is the active component of turmeric; the main anti-inflammatory part. Another fantastic benefit of curcumin is that it inhibits
Here at My Pet Nutritionist, we see quite a few clients with differing bladder stones, often accompanied by other disease. Let’s delve into the different stones and the types of diets we may want to feed. What are Urinary Stones? There are several types of stones that form within the urinary system, each needing a different environment and mineral composition to be able to form. 95% of stones occur within the bladder and only 5% within the kidney, for both cats and dogs. Stones develop when a multitude of microscopic crystals clump together, this doesn’t always happen and so crystals can exist without forming stones. As crystals clump together, they form small stones which can become larger over time and pose more of a problem as the issue gets larger and more painful. When crystals form into small stones they can become life threatening if the stones get lodged in the exit of the bladder thus blocking the exit route. Crystals form from dissolved minerals within the urine in the bladder. These minerals enter the bladder via the kidneys from waste products via food. Altered urinary pH has a role to play in the formation of stones and crystals. Urine pH varies depending on the animal’s diet (Nelson et al) due to the waste products which have been filtered and excreted by the kidney. Symptoms of bladder stones include: Irritation of the bladder lining Blood in the urine Pain when passing urine Urinating small amounts frequently Persistent need to urinate Cloudy or discoloured urine Bloated or sensitive stomach Pain in the abdomen or kidney region Bladder stones are seen more frequently in dogs that experience bladder infections. In our experience we see this due to antibiotic use, a carbohydrate dense diet, poor gut microbiota, food intolerances, food allergies, dehydration and the like. Research has shown some common causes of kidney and bladder stones in canines which tend to be more standard. Causes of these stones can be from the following: Genetics Water Consumption Amount of water in the diet Quantity of and Quality of protein The pH of a dog’s urine Infections Crystals in the urine are diagnosed by a microscopic examination of fresh urine to determine the type of crystal. The urine will also be tested with a strip to determine pH level and presence of blood, White Blood Cells, protein levels and concentration or specific gravity. Determining the type of crystal is very important before we can recommend a suitable diet. These are struvite, oxalate, urate and cystine crystals. Treatment By far the most important way of combatting crystal formation is by adding water to the diet. Feeding moist foods dilutes the urine and promotes more frequent urination. This in turn reduces the likelihood of crystal formation as the urine does not sit in the bladder for so long. Some crystals and stones can be dissolved with dietary supplements alone, changing to a natural balanced wet diet can be enough to irradiate the problem. Some stones cannot be dissolved with diet alone. Other cases need medication or if they are just too large, will require surgical removal. Prescription diets are available with manipulated ingredients and urinary acidifiers. Types of crystals Struvite Magnesium Ammonium Phosphate, triple phosphate Struvite stones are one of the most common types of bladder stones found in dogs. In most cases, struvite bladder stones are caused by infection, namely Staphylococci and Proteus bacteria being the usual culprits. This infection is often contracted from the lower urinary tract. Struvite occurs in alkaline urine (above pH 7) 85% of cases are found in female dogs A meat based diet will naturally make the urine more acidic which can help Often seen alongside recurring bladder infections Supplements tend to assist in creating a healthier pH Helpful supplements – Cranberry extract (Proanthocyanidins, PACs) – proven to reduce bacteria such as E coli Howell AB. Bioactive compounds in cranberries and their role in prevention of urinary tract infections. Mol Nutr Food Res. 2007 Jun;51(6):732-7. doi: 10.1002/mnfr.200700038. PMID: 17487930. – Methionine– is an amino acid that has been proven to acidify the urine Siener R, Struwe F, Hesse A. Effect of L-Methionine on the Risk of Phosphate Stone Formation. Urology. 2016 Dec;98:39-43. doi: 10.1016/j.urology.2016.08.007. Epub 2016 Aug 9. PMID: 27521063. – N -Acetyl Glucosamine – helps bladder support, may reduce inflammation and sooth the bladder wall. Theoharides TC, Kempuraj D, Vakali S, Sant GR. Treatment of refractory interstitial cystitis/painful bladder syndrome with CystoProtek–an oral multi-agent natural supplement. Can J Urol. 2008 Dec;15(6):4410-4. PMID: 19046494. – Apple cider vinegar – is a wonderful anti microbial Yagnik D, Ward M, Shah AJ. Antibacterial apple cider vinegar eradicates methicillin resistant Staphylococcus aureus and resistant Escherichia coli. Sci Rep. 2021 Jan 20;11(1):1854. doi: 10.1038/s41598-020-78407-x. PMID: 33473148; PMCID: PMC7817673. References Bartges JW, Callens AJ. Urolithiasis. Vet Clin North Am Small Anim Pract. 2015 Jul;45(4):747-68. doi: 10.1016/j.cvsm.2015.03.001. PMID: 26002797. Palma D, Langston C, Gisselman K, McCue J. Canine struvite urolithiasis. Compend Contin Educ Vet. 2013 Aug;35(8):E1; quiz E1. PMID: 23677867. Queau Y. Nutritional Management of Urolithiasis. Vet Clin North Am Small Anim Pract. 2019 Mar;49(2):175-186. doi: 10.1016/j.cvsm.2018.10.004. Epub 2018 Dec 21. PMID: 30583809. Calcium oxalate Microscopic Calcium Oxalate crystals The second most common crystal found in dogs, is calcium oxalate. Current research indicates that urine high in calcium, citrates, oxalates and in an acidic environment, predisposes a pet to developing calcium oxalate crystals. Recent studies have shown diets that cause high urine acidity (urine pH less than 6.5) may predispose dogs to develop this type of bladder stone. These occur in neutral to acidic urine (below pH6.5-7) It is not possible to dissolve these so surgery is needed to remove stones Common in Miniature Schnauzers, Miniature Poodles, Yorkshire Terriers, Lhasa Apso, Bichon Fris and Shih Tzu) High oxalate foods to be avoided such as spinach, swiss chard some seeds legumes and berries Probiotics are found to be able to breakdown oxalate in the digestive system. A good broad-spectrum probiotic can contribute to this
