Vaccinosis: Damage Vaccinations Can Cause Your Pet

Autoimmune disease, irritable bowel disorders, lupus, thyroid issues, eisonophilic skin disorders, chronic skin disease and allergic dermatitis, not a list any owner wants to pair with their pet, but sadly all of these diseases can be vaccine-related conditions. We can identify them as vaccine related conditions because symptoms are concomitant with vaccination date. We deem this reaction as vaccinosis. And sadly, it is far more prevalent than we could even imagine. At MPN, we see the correlation of vaccination and disease in many of our clients. So let’s take a look at where we started, and how we ended up in such dire straights. The smallpox vaccine was introduced in 1796 after Edward Jenner observed that milkmaids who had previously caught cow pox didn’t catch smallpox. The idea was that exposure to killed or weakened virus/bacteria that cause disease can prime the immune response, but it doesn’t actually make the host sick. So, vaccinations allow the host to develop immunity without having to suffer the disease. To this end, smallpox is now declared eradicated. There is no doubt that vaccination has been progressive in public health concerns, for both humans and pets, but they were never meant to make the host sick. For a number of reasons, the current vaccinations schedule for our pets, is. There is increasing evidence that over-vaccination is associated with the development or aggravation of immune-mediated disorders and chronic diseases in individual pets that are genetically predisposed. This raises a particularly interesting element that has perhaps been missed when developing the blanket vaccination schedules for our pets. Twin studies, in humans have demonstrated there is a clear genetic role in vaccine response. A growing list of genes have been associated with immune related functions critical to immunological response and much data is concluding it is the status of these genes that is key to immune response. Human data is highlighting that this is one of the reasons vaccines can either elicit partial, complete or failure to protect individuals treated under the same conditions. This would also suggest that the opposite is therefore true; gene status could elicit partial or complete adverse reaction, or hopefully failure to demonstrate adverse reaction. Genes are a set of instructions and there are a number of factors that can affect how they are expressed. This is likely understood in the canine world to some extent because most vaccines are advised as safe for healthy dogs but not those with a compromised immune system. So, what constitutes a compromised immune system? The primary role of the immune system in dogs is to protect against foreign invaders, or abnormal cells that invade or attack. The immune system must distinguish between self and non-self. Substances that stimulate a response are antigens. These can be contained within bacteria, viruses or microorganisms or cancer cells. They may also exist on their own, like pollen or food particles. There are three lines of defence, physical barriers, non specific immunity and specific immunity. Physical barriers are the first line of defence, they include the skin, the cornea of the eye and the membranes lining the respiratory, digestive, urinary and reproductive tracts. The key is to keep these barriers unbroken. These barriers are also defended by bacteria and secretions that contain enzymes that can destroy harmful bacteria. Examples include eye tears, secretions in the digestive tract and the microbiome in the gut. Nonspecific immunity should be present at birth; it treats all foreign substances in the same way. Inflammation results in white blood cells travelling into tissues to kill invading organisms and remove injured cells. Specific immunity is acquired and developed as the immune system encounters different antigens, it learns the best way to attack and develops a memory for that specific antigen. It takes time to develop a response, but in future encounters, the response is more rapid. Specific immunity involves the action of lymphocytes (B and T cells), antibodies, antigen presenting cells and cytokines. Most vaccines work by stimulating the development of specific immunity. But the immune system does not always function properly, it can be underactive and overactive. An underactive system puts the animal at risk of infection, but an overactive immune system can attack parts of its body that it misidentifies as being foreign. This is what happens in autoimmune conditions. The immune system can also overreact and produce too many antibodies or other chemicals; these are what we see as hypersensitivity or allergic reactions. Not only do we have to ensure the physical barriers remain healthy, but we also must ensure that responses are just right. We know that genes play a role in this, but so does the environment your dog (exposure to toxins, chemicals and pesticides etc) alongside nutrition. Each cell in every body uses chemical reactions to build some of the materials that it needs, converting substances provided by the diet into other chemicals necessary for normal functioning. This is why the immune system has its own micronutrient (vitamin and mineral) requirements. For example, Vitamin A helps to maintain structural and functional integrity of mucosal cells in innate barriers like the skin and respiratory tract, Vitamin D stimulates immune cell proliferation and cytokine production, helping to protect against infection, B12 has roles in natural killer cell functions just as folate maintains natural killer cells. Many micronutrients play a role in protecting against reactive oxygen species and reactive nitrogen species which are produced when pathogens are killed by immune cells. Findings here So, there are many things that can compromise an immune system, which also informs whether the dog is a candidate for vaccination and indeed subsequent and frequent booster vaccinations. Signs your Dog may have a compromised immune system: Tiredness/lethargy Increased stress levels Digestive issues Slow healing wounds Frequent infections (eyes, ears etc) Delayed growth/development Skin sensitivities/allergies Joint stiffness and disease Other diagnosed disease If your dog is suffering with any pre-existing health conditions, it pays to consider titre testing. No animal should be vaccinated with a compromised immune system.
To Lepto or not Lepto? That is the Question

A global infection of both humans and animals, leptospirosis is on the tip of most owners and dog professional’s tongue. Caused by the pathogen icleptospira spp. it is a major zoonosis, with infection acquired from wild and domestic animals. Canine leptospirosis presents very similarly to the syndromes presented in other species with hepatic, renal and pulmonary ramifications. In short, it’s pretty rough, but vaccine induced immunity is restricted to serologically related serovars and is generally very short-lived; therefore, needing annual revaccination. If there are more than 230 serovars belonging to at least ten pathogenic species, does the vaccine even pose benefits? Or do the risks outweigh them? We are going to look at the science and explore both sides to this story. Fancy coming along for the journey? Leptospirosis is characterised by fever, jaundice, vomiting, diarrhoea, renal failure, haemorrhages and ultimately death. However, for those who recover, they may become asymptomatic renal carriers for extended periods and shed infectious leptospires into the environment. This is a large source of infection, as rats can be carriers but do not show signs of infection. Whilst treated dogs can shed leptospires, so can vaccinated dogs. This raises the first red flag; is this potentially increasing exposure? Most signs of leptospirosis become apparent in the first week after infection; younger dogs, less than 1 year of age tend to get the most severe forms of leptospirosis and 87-100% of infected dogs will have some degree of renal implication. There do appear to be different clinical parameters of the infection: Peracute Disease: super-sudden onset which usually affects younger dogs with an overwhelming exposure. The large amount of toxin causes rapid death before the kidney or liver disease even occurs. Acute Disease and Subacute Disease: this is the classic form which manifests as fever with bruising and bleeding, general muscle pain and painful abdomen from kidney and/or liver disease. There may be jaundice and inflammation in the eyes. Chronic Disease: recurring fevers, chronic hepatitis, chronic kidney disease, uveitis, poor appetite and weight loss. However, leptospira interrogans sensu lato is sensitive to doxycycline which is a readily available antibiotic. Leptospires are cleared from the blood within 24 hours of starting antibiotics. But it does take around 7 days to clear from the urine. Prognosis, depending on organ damage is 80-90% with appropriate treatment. There are, however, other serovars, like the pomona which is associated with more severe disease and in severe kidney cases, dialysis can be required which is often limited. So, whilst treatment is largely effective, if started soon enough, there was clearly enough concern to develop a vaccine. Vaccination against leptospira interrogans sensu lato is available for the seravars canicola, grippotyphosa, pomona and icterohaemorragiae. Some vaccines coverall four serovars, whereas some cover two of the four. This is where you will recognise the common lepto two or four vaccine. Vaccination against canicola and icterohaemorragiae has been traditional for dogs and vaccination overall, has been seen to reduce the severity of the disease, but will not prevent infected dogs from being carriers. Note, it supposedly reduces severity, it doesn’t necessarily prevent occurrence. The leptospirosis vaccine was soon associated with a higher chance of vaccine reactions. This is a result of human research into leptospirosis. In the U.K. in 2014 , over 2000 reports of Novibac L4 adverse reactions have been reported to the VMD (Veterinary Medicine Directive) and around 120 suspected deaths related to vaccinosis. In addition to this, data suggested that the severity of the disease was associated with the intensity of the immune response. In short, the more intense and early the response, the more severe the disease. Findings here If our immune system, and our dog’s, is primed to take out antigens and protect, why does a more intense response seem to make things worse? An intense immune response induces a high level of inflammatory cytokines which can result in severe tissue lesions. Immunity is like the porridge in Goldilocks. It can sometimes be too cold (lacking) and sometimes too hot (overzealous). Ideally, we want it, just right. There are many things that affect immune responses, in the case of lepto, a more intense response was associated with previous infection. Fever was induced by virulent injection in previously immunised rabbits whereas non-immunised rabbits exhibited no fever after injection. So, in this case, the immunised rabbits fared poorer than non-immunised rabbits. See where we might be going with this? So we are vaccinating to potentially reduce, not prevent the severity of infection but here it appears those rabbits immunised, had a more severe reaction to exposure. But, stress, nutrition and the environment can all affect immune responses too. So too, can genes. This can help explain why some animals are more, or less susceptible to pathogens (or vaccines) than others. And explain the age-old statement, but my dog was fine! It therefore raises no eyebrows when reports appear of clinical leptospirosis in numerous dogs when they had previously been vaccinated. You’ll remember this from earlier, when it was deemed to reduce severity, not necessary prevent occurrence. This was however, associated with vaccine type. In short, the dogs were vaccinated against only two of the many pathogenic serovars. So, in walked Lepto 4. But these new vaccines were associated with further increases in vaccine reactions, not limited to local swelling or hypersensitivity, but including cardiac abnormalities. Specifically, heart murmurs appearing between first and second vaccination. Findings here What is particularly interesting in studies exploring the use of lepto 4 vaccines, is that dogs demonstrated antibodies to serovars not vaccinated against. Researchers have therefore concluded that natural exposure (not vaccine exposure) to serovars provide positive titre results. Not only that, but in cases of vaccinations up to 1745 days previously, some dogs still demonstrated antibodies. This raises a question around the need for such frequent booster vaccinations. The take home from this particular study was “seroconversion following vaccination differed considerably among individual dogs.” Yet they still concluded that, “in the light of the high incidence and
What Food Should My Cat Eat?

Cats are obligate carnivores. What this essentially means is that cats rely on nutrients in animal tissues to meet their specific requirements. Not plants…. but animal tissues. So, let’s explore the world of the cat in a little more detail and see how we can support their nutritional needs to not only survive, but thrive. Evolutionary events have led to a unique digestive and metabolic peculiarity. Whilst in many other species, we have the three macronutrients, fat, protein and carbohydrates, cats seem to have no physiological requirements for carbohydrates. Now where this becomes interesting is that the brain and red blood cells have an absolute need for glucose, and we know that carbs equal glucose, so where do cats get glucose from? Surely without carbohydrates they would be forever hypoglycaemic? Well, through a process of gluconeogenesis, they produce glucose. Us humans, and dogs too can perform this process, but cats have it down to a fine art. Gluconeogenesis is the metabolic process by which glucose is produced from non-carbohydrate precursors, like lactate and amino acids (and we know that amino acids are the building blocks of protein). All amino acids, except leucine and lysine are gluconeogenic and alanine is the major gluconeogenic amino acid. The process mainly occurs in the liver, but some processes are carried out in the kidneys and a small portion is carried out in the intestines. It is thought that cats evolved with the process because of their proportionally large brain. As we have mentioned, the brain has an absolute need for glucose, and it is thought that the brain demand for glucose in cats is around 30% whereas for us humans who have a much larger brain is 44%. Cats wouldn’t have been able to consume high enough levels of carbohydrates from their natural prey diet, so their body had to adapt to survive. This evolution has resulted in a small capacity for starch digestion, having limited salivary amylase which is similar to dogs. Amylase is found in the feline pancreas and chyme, but the activity is incredibly low compared to other animals. Their pancreatic maltase activity is also extremely low. Cats seem to know this and when given the opportunity will choose low carbohydrate but high protein diets in order to balance their own macronutrients. They also don’t appear to have developed a sweet tooth. In evolutionary terms, us humans would have stocked up on sweet-tasting foods, but cats didn’t need to. To that end, they don’t show any preference for natural sugars or artificial sweeteners. In the absence of protein, cats will opt for fat. When fat and protein is limited, but carbohydrate is unlimited, cats appear to experience nutritional deficits. This is largely due to their requirement for taurine. Taurine is present in a range of meats and seafoods but is essentially absent from plant material. This is another reason why cats are deemed obligate carnivores. Dietary deficiency of taurine is linked with a range of important conditions. Retinal Degeneration More commonly known as retinal atrophy, it is the complete or partial wasting of the retina. The cells degenerate over time, eventually leading to blindness in the cat. First signs include the eye being more reflective and the pupils are more dilated than normal. Lesions are usually bilaterally symmetrical. A dietary deficiency must be present for several months before changes appear but lesions are progressive whilst the cat is on a deficient diet, although visual defects don’t tend to appear until the late stages of degeneration. Reproduction Taurine deficiency is well known for having marked effects on reproductive performance and on the growth and survival of the young. Cerebellar dysfunction often occurs in kittens of taurine deficient mothers. Dilated Cardiomyopathy Taurine deficiency can lead to weakening of the muscle cells in the heart, causing a condition called dilated cardiomyopathy (DCM). Taurine is essential in membrane stabilisation. Many cases of feline dilated cardiomyopathy are associated with low plasma taurine levels and when administered with taurine, they show an improvement. Sadly, when left untreated for too long, dilated cardiomyopathy will progress to heart failure and death. The importance of taurine in commercial cat food was noted in the late 1980’s; following reformulation of cat foods, cases of taurine related dilated cardiomyopathy decreased from 28% to just 6%. Findings here Including taurine, eleven amino acids are recognised as essential for the cat, but some have a higher utilisation than others. Taurine is necessary for vision and the function of the cardiac muscle, nervous system, immune system, and reproductive systems. Arginine is used in the urea cycle and methionine and cysteine are incorporated into antioxidants, hair and urinary outputs but are primarily gluconeogenic amino acids, catabolised to provide energy. With their incredible utilisation of amino acids, cats present what is known as a carnivore connection. This is a bundle of carbohydrate-sensitive conditions, first noted in humans who were late to join the carbohydrate-eating party (Paleo-Indians, Australian Aborigines for example). In short, there is a higher incidence of conditions like glucose intolerance, insulin resistance and diabetes. However, other data has suggested that carbohydrate content is of little effect, and these conditions are instead associated with overweight or obese cats. 44% of cats in the UK are deemed as overweight or obese by veterinary professionals. Whereas when surveyed, only 8% of owners think their cat needs to lose any weight. Obesity is defined as abnormal or excessive fat accumulation that presents a risk to health. This is a result of excess calories that the body cannot use; these calories can be from any of the macronutrients. It is often considered that a major factor driving obesity is the practice of free-feeding, in which a bowl of dry food is available for consumption by a cat throughout the day, and simply topped up as it runs out. There is also recent research that suggests feeding cats just once a day may control hunger better than several feeds a day. Findings here This study demonstrated that the cats showed a faster
Tear Stains: Is Your Dog A Cry Baby

Whilst dogs do demonstrate emotions, and you’ve probably seen images doing the rounds on the internet, dogs don’t cry. They have tear ducts like us humans, but when we are balling at the dog dying in, I am Legend, our dog is probably still dreaming of squirrels, KO’d in front of the fire. Not only do our tear ducts allow us to cry, but they form part of a larger system which has a nifty function. This function applies to our dogs too. The Tear System The tear system in the eye keeps it wet enough to be comfortable; you may have come across certain breeds of dog with a condition known as dry eye. This is exactly what it says on the tin, the eye is simply too dry. Tears contribute to eye defences as they contain antimicrobial factors and wash away foreign bodies and dirt. Not only that, but because the cornea has no blood vessels, tears also provide a way of brining nutrients to its cells. The tear system has glands that make the tear fluid, openings that let the tears out and ducts inside of the nose that lets the tears drain through. After washing over the corneal surface, tears flow into the nasolacrimal system, draining into the nasal or oral cavity. The nasolacrimal duct begins with two small openings in the eyelids near the nose, one on the upper eyelid and one on the lower eyelid. Tears are composed of water, electrolytes,proteins, lipids, and mucins; between 60 and 500 different proteins have been identified in tear film. They are seen to have three layers. The mucous layer contains mucins, immunoglobulins, salts, urea, enzymes, glucose, and leukocytes. Mucins form a barrier which protect against pathogens and debris. The gel-like barrier also facilitates the movement of particles, preventing shearing damage. The aqueous layer consists of water, electrolytes, proteins, anti-microbial agents, cytokines, vitamins, immunoglobins, peptide growth factors and hormones. It lubricates, washes away foreign bodies, and nourishes the cornea with oxygen and proteins. Growth factors, vitamins and electrolytes are key to epithelial (cells that line the surface) integrity. The lipid layer, the outermost layer, contains a range of lipids. It reduces evaporation from the underlying aqueous layer and limits contamination from dust and bacteria. Tears are crucial to eye health. Tear secretion is complex. It responds to the conditions faced by the eye, but also influenced by a range of hormones and cytokine balance. Cytokine is derived from two Greek words, cyto meaning cell and kinos meaning movement. Cytokines are cell signalling molecules that aid communication in immune responses. They stimulate the movement of cells towards sites of inflammation, infection, and trauma. Cytokines are agents that modulate or alter the immune system response. Cytokines are classified into: – Lymphokines which are cytokines secreted by T cells and regulate the immune response – Pro-inflammatory cytokines which amplify and perpetuate the inflammatory process – Growth factors which promote cell survival and result in structural changes – Chemokines which stimulate migration of cells – And anti-inflammatory cytokines which negatively modulate the inflammatory response It makes absolute sense that when faced with an ocular threat, cytokine levels increase, presenting as the usual immune response, water and itchiness which is common with seasonal allergies or intolerances. But what is also interesting is that that the rest of the body can also influence tear production. Inflammation is an immunological defence against injury, infection, and allergy. Acute inflammatory response is short lived, levels are altered, the body is primed, the body fights, wins and returns to homeostasis. When there is a prolonged persistence of an antigen, chronic inflammation occurs and can have body wide ramifications. The most considered is how chronic inflammatory diseases of the gut can cause various health issues; inflammatory bowel disease for example is caused by cytokine-driven inflammation of the gut. This leads us to why, no matter what you apply to your white dog’s face, you can’t get rid of those stains. Tear Staining Epiphora as it is technically known is a condition which causes the abnormal overflow of tears. It results in reddish staining around the eyes. The physical shape of your dog can contribute to the development of it; their head shape and where their eyes sit. Some breeds of dogs can over-produce tears due to a turning in of the eyelashes or eyelid. Turning out of the eyelid is also known in Great Danes, Bloodhounds and Spaniels. There may also be congenital abnormalities resulting in too large an opening of the eyelids, common in brachycephalic breeds. Blockage of the nasolacrimal system can also result in the overflow of tears. This can be hereditary but can also be caused by inflammation of infection and in some cases tumour. There is also the risk of a foreign body lodged within the duct. However, inflammation, resulting in the overflow of tears can be infectious or immune-mediated. Supporting your dog’s immune system could be the missing piece of the puzzle when tackling tear staining. Immune Response and Inflammation There are many things that can kick start an inflammatory response in your dog: Untreated acute inflammation such as infection or injury Long term exposure to irritants (chemicals, polluted air etc) Chronic stress Over-nutrition and obesity (increased metabolic processes) Malnutrition But there are changes that can be made. Nutrition and Inflammation Dietary patterns high in refined starches, sugar and saturated and trans fatty acids have been linked to the activation of the innate immune system, resulting in an excessive production of pro-inflammatory cytokines. The consensus is that a less processed diet is associated with reduced markers of inflammation. However, calcium, magnesium, Vitamin D and Omega-3 Fatty Acids are thought to protect against inflammation. Findings here Add foods like green leafy vegetables and fatty fish like salmon, sardines, and mackerel to your dog’s diet. Beef liver is a great source of Vitamin D too! Antioxidants too help counter oxidative stress which is a key player in inflammation. Astaxanthin is a powerful antioxidant found in microalgae. It
Why Your Dog Needs Vitamin B12

Vitamin B12, also known as cobalamin, is a water-soluble vitamin which means no matter how much it is absorbed; any excess will be excreted via urine. It is critical for a range of functions in the body and if you have looked in any multivitamin aisles in the supermarket, it is one of the well-known B complex vitamins. A common deficiency in human vegetarians,disorders of cobalamin metabolism are seemingly increasing in small animal medicine. The causes of deficiency range from chronic gastrointestinal disease to hereditary disease, but what is clear is the health impact of low levels. Suboptimal B12 levels result in: Blood cell count abnormalities Disorders of lipid and protein metabolism Failure to thrive Anorexia Lethargy Vomiting Mood disorders/cognitive decline Slow healing Shortness of breath Muscle weakness Unsteady movement Increased homocysteine levels Functional folate deficiency Because the human body’s stores of B12 can seemingly last 3-6 years, low levels may take a while to be noticed. This seems to be true in our four-legged friends too. So, without further ado, let’s take a look at why it’s so important. Vitamin B12 is essential for DNA and RNA synthesis and for cellular energy production. All cells in all bodies need to know what they are doing and they need energy to do them! There are no known naturally occurring bioactive forms of B12 in plant sources. This is because B12 is synthesised by the bacteria in the gastrointestinal tract of animals, and then absorbed by the host animals. B12 is concentrated in their tissues, which is then eaten by other animals. Sources of B12 include red meat, fish, dairy and eggs. This is why human vegetarians and vegans are often low in it. Once ingested, dietary protein is partially digested by pepsin (digestive enzyme) and hydrochloric acid (HCI). Here Cbl (cobalamin) is released and binds to another protein called haptocorrin. Haptocorrin is then digested by pancreatic proteases (things that breakdown protein); freeing Cbl which can then bind to intrinsic factor. This then forms the B12 complex which travels through the small intestine. Here, there are receptors for intrinsic factor. The complex is internalised into the ileal enterocyte, and then released into the plasma, binding to a plasma protein. B12 is then delivered to those body parts that use and need it. And, there are certain many parts of the body that need and use it. Methionine Cycle B12 plays a vital role in the methionine cycle, which is involved in a range of cellular functions, particularly converting homocysteine to methionine. Methionine can be converted into sulphur-containing molecules which protect tissues,modify DNA, and ensure correct functioning of cells. Methionine also plays a role in creating new proteins in the body, which is essential when older proteins degrade. Whilst it has a role in a range of functions, there have been suggestions that cancer cells too are methionine dependent. Yet, when methionine is replaced with its precursor homocysteine, cancer cell growth is inhibited. Findings here That said, methionine is a key player in producing glutathione. Glutathione is often referred to as the body’s master antioxidant. It is composed of the three amino acids cysteine, glycine and glutamate. Glutathione is an important part of the body’s defence systems. Free radicals are like the exhaust fumes of work, work that the body carries out on a day to day basis. An imbalance in free radicals can result in oxidative stress, something which glutathione can alleviate. Glutathione depletion is often linked with low immune function and increased infection. It has also been found to be protective of skin, lens, cornea and retina damage. Findings here The balance of homocysteine is important,and B12 (along with B6) has the greatest effect on those levels. High levels of homocysteine are often linked to the early development of heart disease, along with Alzheimer’s (in humans), birth defects, blood clots, endothelial damage, and stroke. Resistance to Insulin Mouse studies have suggested that restricted B12 and methionine resulted in an increased resistance to insulin. Insulin is the gatekeeper for glucose getting into cells. Without insulin, glucose remains in the blood without a party to go to. It is argued that the restriction resulted in the lower availability of molecules that are vital to the process of DNA methylation (regulator of gene expression). These gene expressions were modulators underlying the development of resistance to insulin. Findings here Lipid (Fat) Metabolis Low levels of B12 have been noted to increase levels of adiposity, triglycerides, and total cholesterol. It is suggested that deficiency inhibits the oxidation of fatty acids. In these cases, there is also an increase in pro inflammatory cytokines. Findings here The dysregulation of lipid metabolism raises another interesting element. The nervous system has a rich lipid composition. Myelin sheaths are sleeves of fatty tissue that protect nerve cells. These nerve cells carry messages around the body. This is why low levels of B12 can lead to peripheral neuropathy. Without sufficient B12, the myelin sheath is damaged (demyelination) resulting in the disruption of nerve signals between the spinal cord and different parts of the body. This is the same mechanism that occurs in degenerative myelopathy. Whilst it is generally deemed a genetic condition in dogs (specific to certain breeds), in human studies, low levels of B12 have been associated with the condition. B12 deficiency is often a differential diagnosis to degenerative cervical myelopathy in humans too. Findings here Humans with low B12 often report progressive tingling in fingers and toes, without the ability to speak, it is unclear whether these symptoms affect our dogs too, but certainly poses food for thought in itchy cases. Findings here Anaemia The most recognised deficiency of B12 is anaemia. B12 is involved in the formation of healthy red blood cells; anaemia is when the body doesn’t have enough of them. Pernicious anaemia is usually a result of malabsorption of B12 due to a lack of intrinsic factor, the protein found in the stomach. Without enough B12, the red blood cells don’t divide normally (thanks to
Natural Guide for Acid Reflux in Dogs

We see acid reflux rather frequently. It’s usually for a number of reasons and can be a symptom that may end up being more of a problem than anticipated. It’s not a nice thing for doggos to experience and is often telling you something is not quite right and finding out what that is, is paramount. So read on my lovely peeps, resolve your doggo’s blessed reflux. What is acid reflux? Acid reflux in dogs, also known as gastroesophageal reflux, occurs when the acid (chime: mix of acid, salts and bile) from the stomach moves into the oesophagus. It can obviously cause some discomfort and although a symptom in itself (that is not deemed dangerous), it can lead to other issues. Reflux can cause irritation, inflammation and wear on the lining of the oesophagus, leading to possible ulcers. If left for long enough, this can cause narrowing, thinning, or necrosis of the oesophagus. Also a constant regurgitation (a common symptom of acid reflux) can cause vomit to enter a dogs’ lungs and lead to further damage or aspiration pneumonia. Symptoms may be as follows: Bad breath Constipation, diarrhoea and bloating Burping, gagging, or minimal vomiting/regurgitation after a meal Dry cough Wheezing Pain after eating, such as restlessness and hunching over Inactivity or lethargy after meal Loss of appetite Weight loss There are many factors that may cause GERD, and these should be systematically evaluated when creating a treatment plan, aiming to address the reason as opposed to the disease itself. What role does acid play in the gut? Appropriate acid levels in the gut are paramount. HCL is also responsible for breaking down dietary proteins aiding in the absorption of nutrients. Healthy levels of acid (HCL) eliminates bacteria and viruses and prevents the overgrowth of pathogens in the upper GI tract, so hypochlorhydria (low HCL) can be a risk factor for SIBO (small intestinal bacterial overgrowth), fungal overgrowth, intestinal permeability and possible sensitivities and allergies. Acid in the stomach can be too high but most commonly, is presents as too low, incapable of fully digesting and emptying food into the small intestines, allowing chime to sit in the stomach and allowing regurgitation. There is often the misconception that it’s often too high and therefore must be suppressed by drugs. Research has proven that a lack or suppression of gastric acid (HCL), has been associated with an increase in bone fractures, possible autoimmune disease, impaired absorption of B12, iron and magnesium. Poor gut health and reflux can be linked to allergies, arthritis, autoimmune disease, itching and rashes, fatigue, anxiety, cancer, and so much more. In short, if the gut isn’t functioning at full capacity, then neither is your pet’s health. Why is your dog experiencing acid reflux? Stress is often a low grade release of cortisol that can slow down digestion, creating a bolus of food in the stomach, that can sit around, coming up as regurgitation, rather than emptying into the small intestines in a timely fashion. Poor gut motility sometimes linked to poor food (dry food) or neurological dysfunction. Structural issues can be the cause such as obstruction, a loose dysfunctional lower oesophageal sphincter, hiatal hernia or inflammation caused from disease such as megaesophagus. Food intolerances, sensitivity and allergies can create immune dysfunction and a less hospitable digestive environment. Poor gut microbiota, yeast overgrowth, bacterial overgrowth, SIBO (small intestinal overgrowth), sometimes from antibiotic use. Poor immunity and gut immunity (integrity of the ‘one cell epithelial of the gut’), can cause inflammation and a lower level of acid which can slow down protein digestion and cause regurgitation. Disease such as a liver disease, pancreatitis, IBD (inflammatory bowel disease). Nutritional deficiencies. Being overweight. Conventional Veterinary Approach to Acid Reflux Vet’s often used drugs as an intervention and whilst it might alleviate initial symptoms, it is not a long term solution and implicates longer term issues. Proton pump inhibitors (PPIs), inhibit the gastric acid production and are amongst the top 10 most commonly prescribed drugs in the world for humans and pets. Pro-kinetic medication is sometimes used to help move food through the digestive system and strengthen the oesophageal sphincter muscles. The above aren’t really successful options long term and most certainly do not address the cause. Whilst inhibitors may give short term relief, a more holistic approach is far more successful than unnaturally suppressing HCL levels. The conventional approach generally believes that acid is overproduced. Whilst this is possible, it is deemed to be the reverse in many circumstances. How Diet and Supplements can Help The gut is the epicentre of immunity and health. If your dog’s digestive system is not working correctly, then nothing else will be. A symptom of acid reflux is telling you there is a dis-ease in the body and something needs to change to rectify it. Determining the reasons why are key. Is the food suitable for your dog? Are you feeding a commercial dry food? Are there nutritional deficiencies? Is there stress? Is the gut functioning properly? Nutrition Looking at suitable diets and food for your pet is essential. A fresh and balanced diet rich in easily digestible proteins, good fats and vegetables (fibre) can help support gut microbiota and stomach acid levels. Home made cooked or raw food are often best in this instance Findings here Processed foods and sugars can cause inflammation in your dog’s stomach, decrease acid levels, triggering acid reflux symptoms. Certain foods can often be an aggravator of reflux, so understanding what might be bothering your dog is essential. If feeding a fresh diet has not worked and you are at a loss. Doing a food sensitivity test can help in removing the culprits. An elimination diet is the best way forward as intolerance and allergy testing can be inconclusive. Low dietary fibre intake is associated with decreased stomach and gut motility and delayed gastric emptying. Low fibre findings are mostly found in humans, but our counterparts experience the same pathogenesis in acid reflux and adding insoluble fibre, may help. Findings here Checking
The 4 Corner Stones for Healthy Anal Glands, Naturally

We can’t tell you how much My Pet Nutritionist talk about anal glands and pooping with people. We can wake up to pictures of my client’s dog’s poop on my phone (on a daily basis). It’s a real thing people! Anal gland issues and sloppy pooh are problems that you pet parents come up against every day. We know from research, that just over 10% of dogs will have issues with their anal glands, in their lifetime. Cat’s also have anal glands but we don’t see this issue crop up in the vets as commonly due to the nature of their social habits. Although anal glands are supposed to empty as faeces are passed, this doesn’t always happen. Over time the anal glands can fill up and can become inflamed, impacted and pretty painful. There can be many reasons why, some simple and some more complex. There are a lot of things we can do naturally for anal gland issues, so read ahead peeps. Function and Symptoms The anal glands function is to release pheromones, enabling the communication between dogs and other mammals, including cats. The anal glands located on the lower sides of the anus, produce a fluid with a scent that identifies him or her, communicating sex, health and approximate age to other animals. This is the reason why dogs sniff each’ others bottoms and love mooching for ‘scents’. These sacs excrete fluid when the dog/cat has a bowel movement. Discharge in the anal glands should be liquid and if the ducts are open then your dog should have no issues. As faeces pass through the anus, the anal glands become expressed and voila, pheromones are released and communication with the outside world begins. If your dog has impacted anal sacs, they will experience some or all of the below symptoms: Scooting (dragging bottom on the floor) Licking or biting at the bottom area Difficulty sitting or standing On rare occasion, chasing the tail Some vets may recommend removing the glands if the problem is consistent and severe but this SHOULD NEVER HAPPEN, unless there is disease of the glands, such as cancer. Personally, I’ve seen some awful cases with removed anal glands, as it disrupts the function of the anal sphincter and interferes with the body’s ability to cleanse. They are really unwell dogs and end up displaying other issues, longterm, that are incredibly difficult to support. Always seek a second opinion. It’s all in the Pooh Poor quality bowel movements can contribute to anal glands becoming impacted. So what should a healthy stool look like? To fully express the anal glands, the faeces need to look quite bullet like, powdery and dry. Your dog should not strain but a firm, pick-up-able poop, that one is able to hold between the thumb and middle finger (without it breaking), is an optimum poop. This will aid in the anal glands expressing more efficiently. Check out our guide on pooh here. The Ultimate Dog Pooh Guide Other reasons for Anal Gland Issues Sometimes a dog’s anal sac issues can be a symptom of broader systemic issue. This is where our consultation services can be really help. We often find by looking at the 8 systems cycle in functional medicine, we can consider every element of health and see what might be under lying. So here is how we look at the problem. Stress; low grade stress (commonly experienced by many dogs) can interfere with the function of the gut, slowing digestion and the transit of food. Gut microbiota (good bacteria) that supports digestive function can also be destroyed by the effects of stress. Addressing stress can be really helpful. Digestion; poor quality bowel movements can contribute to anal glands becoming impacted. Constipation and diarrhoea can produce stool that isn’t sufficient for the task of emptying the anal sacs. This often allows for constipation or diarrhoea, preventing solid faeces passing over the anal sacs. Supporting healthy levels of digestive and pancreatic enzymes and good levels of gastric juices (HCL), are incredibly important for a healthy functioning bowel. SIBO (small intestinal bacterial overgrowth) and yeast infections have potentially been linked to more frequent anal gland issues. Good bacteria in the gut is essential for optimal function, preventing bad bacteria and yeast overgrowth. Also checking for worms and parasites can be helpful in anal gland dysfunction. Immunity; food allergies, intolerances or sensitivities are due to an under functioning or overly sensitive immune system. It is key to establish if your pet is reacting to any foods, as this can affect digestion. By eliminating them, rebuilding immunity (gut) and addressing inflammation, this can directly impact your pet’s digestive system and anal gland excretion. Neurological; many nutrients are essential for the nervous system and this is a complex system. One key mineral is magnesium, essential for neurological function and in particular the vagus nerve that connects the gut-brain axis. Deficient magnesium can cause a slow ‘peristaltic’ movement within the bowel (a motion that pushes food through the bowel). If this isn’t functioning well, the slow passage of food can equal slow transit of food, creating constipation, slow detoxification and impaired anal sac fluid emptying. Detoxification; is a network of systems but the liver and gallbladder are most closely connected to digestive function helping with fat digestion (emulsification). The liver must be working effectively for the digestive system to work efficiently and reduce the toxic load on the anal glands. Structure; hereditary malformations of the anal glands could also be a cause. This is less common but worth exploring if nothing seems to help. Structure and integrity of the connective tissue with regards to stomach muscles, back muscles, back legs and so forth is supportive in allowing your dog to defecate effectively. Stooping, squatting and pushing all require strength of the body. Some dog’s who are lame will have problems expressing. Working on the structure of your dog’s body can be helpful, if this is an issue. Hormones; low oestrogen can lead to chronic constipation in
7 Top Reasons to use Clay in your Dog’s Diet Regime

Here at MPN, we see a number of different cases whether it be itching/allergies, cancer, pancreatitis, IBS, IBD, liver and kidney disease and more. There’s a lot that goes into a consultation at MPN and its bespoke to your pet. No 2 clients are going to get the same plan. However, Bentonite clay is one of the ingredients can that be applied to a lot of these problems as an initial support. So, let’s get the dirt on clay! See what I did there? Does your dog dig for soil or want to eat cardboard? Does your cat try and eat litter? Then Bentonite could be just what they are looking for. Clay has been used with the following issues successfully and supported by research for both humans and animals: · Skin issues and Allergies · Digestive issues · Pancreatitis · Kidney and liver Support · Immune support · Parasites · General detoxification My favourite, which is Bentonite clay, can be interchangeably referred to as Montmorillonite clay and are both regarded as an absorbent aluminium phyllosilicate clay from the Smectites family. They are both named after regions they come from but in nature they have the same structure and have a much higher absorption capacity than other clays found in nature and on the market. It has been used and eaten since ancient times as humans believed in its therapeutic benefits. So let’s chat about Bentonite clay and its wondrous abilities. Skin issues and Allergies Due to many skin issues arising from immune reactions and toxicity, Bentonite can be calming and cooling both applied internally and externally. Internally Bentonite clay has proven to remove many different bacteria and fungi, including candida albicans, that can lead to skin issues. It can help support and excrete histamine from the bowel (histamine, we know can create intense itching and can accumulate whether your pet is experiencing allergies or not) and clay can help support liver and kidney function which is essential when detoxification is required due to the above. Applied externally (clay being wet and made into a paste) can help hotspots, wounds, calm itching and help fungal infections. This is our favourite on the market for EXTERNAL application only. Digestive issues Clay can positively affect digestion by boosting gut flora and ridding the digestive tract of any unwanted toxins. One trial states that bentonite may help nutrient absorption through increasing gut flora activity. We know gut flora (microbiota is essential for digestive health and good immunity). Bentonite clay has for a long time been considered as an effective treatment for diarrhoea, IBS and IBD. A trial in 1961, was shown that orally administered bentonite treated 97% of cases with different causative factors of diarrhoea. These being virus infection, food allergy, spastic colitis, mucous colitis, and food poisoning. This is pretty incredible don’t you think? Pancreatitis Clay can be a wonderful addition to a diet in EPI(Exocrine Pancreatic Insufficiency) especially when stools are upset and voluminous. In pancreatitis the pancreas becomes inflamed and enzyme production is less than desired. A trial with montmorillonite clay improved diarrhoea, enhanced intestinal mucosal integrity and the production of digestive enzymes in animals found here. Kidney and liver Support Bentonite can really help kidney and liver function. Two examples of how this may help. Bentonite is a natural phosphate binder which is a essential support in kidney disease. The excess phosphates and urea that the kidneys can’t clear can be greatly helped by Bentonite clay and will allow your pet to feel much better, improving appetite and energy level. SerumUrea is a by-product of kidney disease and poor function. Bentonite is shown to promote the diffusion of urea from blood vessel to intestine, and inhibits the absorption of urea in intestine here. Also Bentonite clay was able to restore liver function during exposure to toxins. And it didn’t affect their digestion of good nutrients here. Immune support We know Bentonite clay supports digestion and over 70% of the immune system resides in the digestive system. We know effective detoxification supports general immune function but we also know cancer and Bentonite have a direct correlation. Bentonite has been shown to inhibit the growth of human cancer cell lines U251 (central nervous system, glioblastoma). It seems that bentonite clay surfaces, controls the levels of metabolic growth components here. It has also been shown to demonstrate an anti-bacterial affect and the ability to pull pathogens out of the bowel here. Parasites Bentonite helps to clear intestinal parasites by dehydrating them, binding to them and then pulling them out of the body. Clay may also be used externally to suffocate and kill parasites on your pet. Dry powder can be put over your pet’s coat or pasting wet clay for a period of time. Just to warn you folks, this could get messy. General detoxification Clay has first and foremost always been considered as a detoxifier. It ultimately helps many of the above issues due to its detoxifying nature. Bentonite clay is negatively charged and so manages to attract and pull out toxins that by nature are positively charged. Clever isn’t it? If your pet has been on a processed diet, been exposed to allergens, pathogens, parasites, vaccinations or just plain fatigued and trying to eat soil, then Bentonite clay is a wonderful supplement to consider. Clay is basically ideal for most of the pet population if taken with caution. How to use Bentonite Clay Bentonite clay needs to be given on an empty stomach and not to be fed food, herbs or medications until at least 2 hours after consumption. Please make sure dose is considered for your pet’s size and health and check with a healthcare professional first if unsure. Also select a reputable and established supplemental clay as it can naturally contain heavy metals and quality can differ between brands. Caution must be taken when given and reassessed after a period of administration. Make sure clean and filtered water is available at all time. The very essence of
Itching has become such an epidemic

This might be as dry as a rice cake and to be honest, we thought we might be able to put you to sleep but all joking aside, although this blog doesn’t give you exact solutions, you can see how we look at allergies and how we approach itchy pets with great knowledge and success. Now put on the kettle and don’t read this horizontally in bed; falling asleep is guaranteed. Although this is from a scientific and pathophysiological perspective, I’m yet to meet a conventional veterinarian who looks at itchy pets in the same way. Allergy/itching is one of the most prevalent problems seen by vets and My Pet Nutritionist to date. It’s almost become our life’s work to understand how and why this happens as we get clients everyday with the same issues. Natural means is really the only way to go to solve this issue but to do this successfully, we need to understand the complex immunity and physiological pathways and address is with nutrition and supplements. In short, itching and allergies are due to an overactive and underachieving immune system as well as possible genetic and nutritional snips and deficiencies. The immune system is so finely tuned you wouldn’t get your breath. There’s so much we don’t know and some of the following has thin scientific research. In more than basic terms the immune system is split into 2 parts, Th1 and Th2 (actually there is a more newly discovered TH3 and TH17 but let’s not complicate things). Both parts should work in harmony and balance. Th1 and Th2 cells are maintained in a carefully regulated balance. If a bacterium enters the body, it activates Th2 cells that dominate the network to begin a cascade of immune events leading to an antibody response that clears the infection. If a virus enters cells in the body, it activates Th1 cells which dominate and instruct the killer cell response to clear infected cells. Once the infection is cleared up, suppressor cells are activated to shut down the dominate response and bring the network back into what we call a resting state. If the suppressor cells do not act to bring the network back to a resting state, a pathological Th1-or Th2 dominated immune system results. A Th1 dominated immune system is characteristic of food intolerances and autoimmune diseases, such as type 1 diabetes where the immune system is attacking normal tissues. A Th2-dominated immune system is characteristic of allergies and cancer and so forth. The incessant itching arises from an excessive and dominant reaction in the immune system. In Th2 allergic reactions (IGE), histamine is the compound released. There are several things we need to consider to piece it all together. Breeding has a lot to do with it and can dominate how well they will be in life, unless you have people like us on board. Factors to be considered are: Genetics; it’s like a lottery and no matter what kennel club certifications you have there are no guarantees. Certain breeds are always more at risk. Foetal development and birth; how healthy is the mother, what is she fed and how many litters she has sired previously, all come into play. Certain breeds don’t experience the healthy birthing through the canal such as some French Bull dogs. C-section is proven to under develop the much needed microbiota in your pet’s gut and can pre determine how balanced immunity will be. During pregnancy the mother is TH2 dominant which means so is your pup or kitten when born, this is cleverly put back into balance during weaning. Breast feeding and weaning; feeding from mother and getting the first colostrum and being fed like this for a good 10-12 weeks is so important for immunity and reactions. Many people arrive home with their new pet at 8 weeks’ old which is way too young. This might not allow for puppy or kitten to modulate immunity and come out of TH2 dominance and balance nicely. Environmental challenges in the early months; Initial vaccinations are important but timing is essential in allowing the immune system to respond accordingly. Also being exposed to different proteins and a healthy diet helps build a positive immunity and reaction to foods in future months.The first few months determine a lot and you don’t always have control over this. How our pet interfaces with the world, very much dictates whether immune dysfunction comes into play from the above points. The below considerations need to be looked at in its entirety not individually. Causative factors of itching to be considered: Physiological and emotional stress; we know stress triggers inflammation and a TH2 dominance, those with allergies are naturally be more TH2 dominant. Intestinal permeability; allowing for the escape of undigested proteins and pathogens through the gut wall and directly into the bloodstream, evoking prolonged inflammatory immune responses. Stress, diet, poor microbiota and environmental toxins can all destroy epithelial mucosa that cause intestinal permeability. Altered gut microflora; c-section, early weening, stress, diet, hormones and so on can effect gut bacteria and immunity. Hormonal imbalances; cortisol, oestrogen, thyroid hormones are actively associated with histamine behaviour and imbalance of immunity TH2 dominance. We de sex most of our dogs and wonder why they have so many issues. I’m glad no one gave me a hysterectomy in my first few years of life. Diet & nutritional deficiency; poor or an inappropriate diet can trigger TH1 or TH2 dominance and so will make reactions worse. Some foods such as wheat, grains, soy, gluten and corn are known foods to elicit reactions but it can get really complicated. Vitamin D and zinc are the most prevalently deficient in animals with allergies. Genetics; certain genetic polymorphisms affect immune TH1/TH2 dominance, DAO/MAO polymorphisms mean genetically your pet is less able to metabolise/breakdown histamines in the body. We know histamine to be the most related immune response to intolerances and allergies (a.k.a Histamine intolerance). Blog on Histamine Intolerance here. Heavy metal toxicity; we don’t need
An itch you just can’t scratch!

Many clients come to My Pet Nutritionist with their itchy pet, usually dogs, in complete dismay after trying several things to alleviate the itch. Some of these wonderful people have gone all out, trying a fresh diet, raw food, supplements, testing for food and environmental allergies, food sensitivities and so on. Whilst being armed with lots of information and avoiding the ‘supposed culprits’ the itching has not got any better. If anything, at times, it seems worse. We have specialised in functional medicine for a very long time and in the exciting world of human nutrition, we are closely studying genomes, genetic polymorphisms and how nutrition can influence health, based on our genetic make-up. Welcome to the world of epigenetics and nutrigenomics! Although we are studying the dog genome (not cats of yet), we are far behind in comparison to the world of human nutrition. Dogs in particular share a lot of the same pathophysiology in function and disease. We have therefore applied a lot of what we have learnt and researched in the human arena to pet’s health and gaining some great results. In particular, with itchy dogs and what we know in human nutritional terms as ‘histamine intolerance’. Histamine is a necessary part of physiological functions in animals such as protecting against infection and inflammation. It regulates gut function, especially the release of gastric acid as part of the breakdown of proteins in the digestion of food, it acts as a neurotransmitter affecting cognitive function and in dogs helps to deal with anxiety. Histamine is either stored or inactivated by degradative enzymes, Histamine-N-methyltransferase or Diamine Oxidase (DAO). DAO will reside in the GI tract where nearly all histamine from food is metabolised (destroyed/eliminated) by DAO. Due to genetics or nutritional deficiency DAO and Histamine-N-methyltransferase production can be lacking and therefore histamine can build up and here in lies the problem. Histamine can also be naturally occurring in foods or can release additional histamine known as a ‘histamine liberators’. Those naturally containing high histamine foods are often fermented such as kefir and sauerkraut and other foods such as tomato and spinach. Foods known as liberators are those such as strawberries, citrus fruits and nuts. Histamine levels only continue to rise the longer the food sits within the gut and ferments. You’ll find many nutritionists are recommending fermented foods for digestive health and itchy dogs. This can make the problem 10 times worse until the issue at hand is resolved. Even certain drugs such as antihistamines can cripple DAO function and make symptoms worse. So you see, even if you remove foods that you know your dog to be intolerant or allergic to, if they eat foods containing or releasing high amounts of histamine or don’t naturally produce enough enzymes to break them down, symptoms won’t be relieved. In our practice we go on a naturally low occurring histamine diet, considering the reactivity of the immune system, improve DAO and methylation function by adding in certain nutritional ingredients such as magnesium, vitamin C, B6, methyl folate etc, all whilst considering every system within the body. To find out more or to book a consultation with MPN, please check us out. We hope this helps folks! MPN Team x
Itchy cats and dogs naturally!

Looking from a holistic perspective, there are many factors as to why a dog may be predisposed to being itchy. This could be genetics, the environment and how effective a dog’s immune and detoxification system is. We live in a highly toxic environment where our pets are often over vaccinated, fed highly processed diets and have those genetic predispositions we just mentioned. Puppies are also all too often weaned off of mother’s milk too early, to allow for a fully acquired immune system. There are a few reasons why your pet could be itchy but either way, it’s a physiological, immunological response that needs to be put back into balance. Whilst detecting the reasons why, addressing the inflammation caused, can sometimes be tricky. Hundreds of cats and dogs have come to us with the complication of knowing what elicits the reaction but even still, can’t get a handle on the scratching. This is where we use a layered approach to looking at all elements of the physical body. The cause of itching in dogs is largely due to allergies. Approximately 1 in 5 dogs have allergies that are often diagnosed as Atopic or Contact Dermatitis. This could be from a number of allergens such as grass, moulds, foods, household items and parasites. Allergies in dogs often manifests in constant scratching, rashes, ear infections, weeping eyes and hotspots and can become a real problem for dogs and their owners. It’s actually one of the most common complaints we see in clinic today. So your cat or dog is probably scratching, licking their paws, backs of legs and belly. They may also be sneezing, have weeping eyes and ear problems. To start to fix a problem, we need to know what is causing it. There are generally 3 main reasons why your dog may be itchy. Understanding the causes can help us in our steps to an itch free dog. 1. Environmental allergies. This is caused by inhaled allergens and this could be to certain pollens, dust, mould, household products and may be all year around or just seasonal. An environmental allergy accounts for the majority of dermatitis in dogs. 2. Food allergies are less common but intolerances and sensitivities are very common. The most common food suspects are corn, maize, chicken, beef, soy and gluten but the list can be endless. 3. Contact allergies.This is often a reaction to parasites such as fleas, or mange, grass or household products such as detergent you’ve used to wash bedding for example.Flea contact dermatitis is probably the most common of all of these. It’s important you get a diagnosis by your vet or a clinic like My Pet Nutritionist, as we need to know what your dog is reacting to. In rare cases itching can be due to more serious disease such as kidney disease or thyroid disease, so make sure you get this checked out by a professional. Many tests for sensitivities and allergens are not very accurate but for foods we currently use Nutriscan. http://www.nutriscan.org Environmental allergy testing is some of the most accurate and we suggest going to your vet for this. Allergies are caused by an overactive immune system that perceives harmless substances as threats and intolerances caused by poor functioning gut health. Once we identify those substances, removing them are important but we still need to consider other steps to get results. Imagine your immune system is a scale. It’s tipped far one way and we need to get it back into balance. Quite often, if the offending allergens, foods etc are removed, your pet can still experience itching. Each positive step you take is one step closer to that scale being completely in balance. Supporting digestive health can be a first step in aiding allergies and intolerances. Nutrition Poor quality food in itself generally depletes the body and immune system. You see, it’s all about the immune system working effectively for an itchy dog. Many commercial diets are lacking in antioxidants and enzymes that are abundant in fresh, raw foods and lightly cooked foods. These elements are essential to well-being but are killed by high heat processing in all of the cooked, packaged dry and tinned foods on the shelves today. Dry food for example contains very high starch content even if your dog food does not contain grain. The starch is required to stick the kibble together and starch equals a high sugar content. Sugar is bad for your cat and dog as the sugar can feed different bacteria, virus, yeast and cancer. Not to mention itching dogs. If you suspect your pet has a food allergy or sensitivities and you haven’t done a test yet or the test is inconclusive, then an elimination diet also known as a ‘feeding trial’ can be a thorough way to detect the offending foods. An elimination diet involves feeding an extremely simplified diet for 12 weeks observing any signs of intolerance such as itching, diarrhoea, weeping eyes and a yeasty smell. After 12 weeks of a simplified and uniform recipe, we start introducing different protein sources and sticking to one per week and observing reactions. It’s always good to start with single proteins your cat or dog has not previously been introduced to such as kangaroo or horse. Don’t feed treats other than the pure meat you are feeding for main meals that week. Treats if possible should be avoided. Clean filtered bottled or even better still, distilled water should be given, not regular tap water. Sometimes we check for allergies and intolerances and there aren’t any. This could be simply because the coat and skin is dry and there’s a lack of omega oils in the diet (this should always be considered first), but sometimes and more often there’s an issue called Histamine Intolerance. Detoxify General lifestyle choices and toxic overload, challenges the immune system and puts it under more pressure every day. To help the itch, we must remove toxicity in your cat and dog’s life. Your